cd95 death-inducing signaling complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. (Gene Ontology, GO_0031265)
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23 proteins co-occuring with the cd95 death-inducing signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FADD Fas (TNFRSF6)-associated via death domain 1.90493
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.84019
FAF1 Fas (TNFRSF6) associated factor 1 1.64314
CFLAR CASP8 and FADD-like apoptosis regulator 1.12399
AATF apoptosis antagonizing transcription factor 1.08425
DEDD death effector domain containing 0.918111
FASLG Fas ligand (TNF superfamily, member 6) 0.834597
STAP2 signal transducing adaptor family member 2 0.683335
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.660345
BCL2L1 BCL2-like 1 0.587199
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.568832
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.565508
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.552664
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.503506
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.492157
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.464397
CARD17 caspase recruitment domain family, member 17 0.456809
TRAF2 TNF receptor-associated factor 2 0.445672
UBD ubiquitin D 0.444482
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.430253
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.411039
SUMO1 small ubiquitin-like modifier 1 0.304027
BTK Bruton agammaglobulinemia tyrosine kinase 0.193394