cd45 deficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A severe combined immunodeficiency that is an autosomal recessive disease with T and B lymphocyte dysfunction, due to a large deletion at one allelle and a point mutation at the other. The point mutation resulted in the alteration of intervening sequence 13 donor splice site. The population of T lymphocytes is diminished and unresponsive to mitogen stimulation. The level of B lymphocyte numbers, serum immunoglobulin decreased with age. (Human Disease Ontology, DOID_0060014)
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Genes

16 genes co-occuring with the disease cd45 deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.526
PTPRD protein tyrosine phosphatase, receptor type, D 1.51809
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.36727
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.21825
PTPRJ protein tyrosine phosphatase, receptor type, J 1.03198
LCK LCK proto-oncogene, Src family tyrosine kinase 0.939534
PTPRC protein tyrosine phosphatase, receptor type, C 0.565666
LGALS1 lectin, galactoside-binding, soluble, 1 0.458996
DLL1 delta-like 1 (Drosophila) 0.449947
SYK spleen tyrosine kinase 0.42814
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.317909
THY1 Thy-1 cell surface antigen 0.274021
CXCL12 chemokine (C-X-C motif) ligand 12 0.21974
PLCG1 phospholipase C, gamma 1 0.17952
CD4 CD4 molecule 0.167224
CD5 CD5 molecule 0.15948