carteolol-4096 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the carteolol-4096 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADAM20 ADAM metallopeptidase domain 20
ADAP1 ArfGAP with dual PH domains 1
ADRA1A adrenoceptor alpha 1A
ALDOB aldolase B, fructose-bisphosphate
AOC3 amine oxidase, copper containing 3
APOA1 apolipoprotein A-I
ARMCX4 armadillo repeat containing, X-linked 4
BAAT bile acid CoA:amino acid N-acyltransferase
BCAM basal cell adhesion molecule (Lutheran blood group)
BHMT2 betaine--homocysteine S-methyltransferase 2
BTG2 BTG family, member 2
C1S complement component 1, s subcomponent
C2CD2L C2CD2-like
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC71 coiled-coil domain containing 71
CCND2 cyclin D2
CD300C CD300c molecule
CDC14A cell division cycle 14A
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CLCN4 chloride channel, voltage-sensitive 4
CLEC1A C-type lectin domain family 1, member A
CLTA clathrin, light chain A
COL14A1 collagen, type XIV, alpha 1
COL1A2 collagen, type I, alpha 2
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
EHD2 EH-domain containing 2
EIF3F eukaryotic translation initiation factor 3, subunit F
ELK1 ELK1, member of ETS oncogene family
ESRRG estrogen-related receptor gamma
FAXDC2 fatty acid hydroxylase domain containing 2
FCAR Fc fragment of IgA receptor
FGF16 fibroblast growth factor 16
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GALR3 galanin receptor 3
GFER growth factor, augmenter of liver regeneration
GJD2 gap junction protein, delta 2, 36kDa
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HIST1H2AL histone cluster 1, H2al
HLA-DOB major histocompatibility complex, class II, DO beta
HPR haptoglobin-related protein
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB8 integrin, beta 8
KIF1C kinesin family member 1C
KLK2 kallikrein-related peptidase 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MGAT4C MGAT4 family, member C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MNDA myeloid cell nuclear differentiation antigen
MYF5 myogenic factor 5
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NIPAL2 NIPA-like domain containing 2
NPR1 natriuretic peptide receptor 1
NRXN3 neurexin 3
NUP214 nucleoporin 214kDa
ONECUT1 one cut homeobox 1
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PAX7 paired box 7
PCDHB3 protocadherin beta 3
PDE11A phosphodiesterase 11A
PDE12 phosphodiesterase 12
PHF3 PHD finger protein 3
PLCD1 phospholipase C, delta 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKG2 protein kinase, cGMP-dependent, type II
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTPRB protein tyrosine phosphatase, receptor type, B
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHEB Ras homolog enriched in brain
RHOBTB3 Rho-related BTB domain containing 3
RPLP2 ribosomal protein, large, P2
SAMD4A sterile alpha motif domain containing 4A
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SOX5 SRY (sex determining region Y)-box 5
SPICE1 spindle and centriole associated protein 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF7 serine/arginine-rich splicing factor 7
SSX5 synovial sarcoma, X breakpoint 5
ST18 suppression of tumorigenicity 18, zinc finger
STAB1 stabilin 1
STOML1 stomatin (EPB72)-like 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT12 synaptotagmin XII
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBXA2R thromboxane A2 receptor
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TRGV5 T cell receptor gamma variable 5
TRIM3 tripartite motif containing 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF334 zinc finger protein 334
ZNF536 zinc finger protein 536

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AKAP5 A kinase (PRKA) anchor protein 5
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARPIN actin-related protein 2/3 complex inhibitor
ARR3 arrestin 3, retinal (X-arrestin)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AXIN1 axin 1
BICC1 BicC family RNA binding protein 1
BMP10 bone morphogenetic protein 10
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
C1R complement component 1, r subcomponent
C3AR1 complement component 3a receptor 1
C5ORF45 chromosome 5 open reading frame 45
CD82 CD82 molecule
CDH7 cadherin 7, type 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLDN1 claudin 1
CLIC3 chloride intracellular channel 3
CNTNAP1 contactin associated protein 1
CREB5 cAMP responsive element binding protein 5
CYB5R2 cytochrome b5 reductase 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNM3 dynamin 3
DPYS dihydropyrimidinase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHX2 epoxide hydrolase 2, cytoplasmic
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
FBRS fibrosin
FKBP10 FK506 binding protein 10, 65 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
GDAP1 ganglioside induced differentiation associated protein 1
GMPR guanosine monophosphate reductase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHAT hedgehog acyltransferase
HSF2BP heat shock transcription factor 2 binding protein
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT140 intraflagellar transport 140
IL18R1 interleukin 18 receptor 1
IL36RN interleukin 36 receptor antagonist
INO80D INO80 complex subunit D
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0513 KIAA0513
KIAA1456 KIAA1456
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC390998 ribosomal protein L10 pseudogene
LRP4 low density lipoprotein receptor-related protein 4
LRRC2 leucine rich repeat containing 2
MB myoglobin
MTCP1 mature T-cell proliferation 1
MYO1F myosin IF
NCS1 neuronal calcium sensor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NPDC1 neural proliferation, differentiation and control, 1
NPFFR1 neuropeptide FF receptor 1
NPPB natriuretic peptide B
NTSR1 neurotensin receptor 1 (high affinity)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHGB5 protocadherin gamma subfamily B, 5
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS22 protease, serine, 22
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
SCGB2A1 secretoglobin, family 2A, member 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC16A6 solute carrier family 16, member 6
SLN sarcolipin
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STEAP4 STEAP family member 4
SYT17 synaptotagmin XVII
TBKBP1 TBK1 binding protein 1
TMEM19 transmembrane protein 19
TRAF2 TNF receptor-associated factor 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN2 tetraspanin 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR62 WD repeat domain 62
ZNF268 zinc finger protein 268
ZNF549 zinc finger protein 549
ZNF778 zinc finger protein 778
ZW10 zw10 kinetochore protein