carotid artery disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

261 genes co-occuring with the disease carotid artery disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HABP2 hyaluronan binding protein 2 1.64173
CRP C-reactive protein, pentraxin-related 1.36858
F3 coagulation factor III (thromboplastin, tissue factor) 1.19964
PLAT plasminogen activator, tissue 1.15965
PGRMC1 progesterone receptor membrane component 1 1.15624
LDB2 LIM domain binding 2 1.06396
SYS1 Sys1 golgi trafficking protein 1.06018
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.02187
MMP9 matrix metallopeptidase 9 1.01427
CD68 CD68 molecule 1.00794
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.991909
APOB apolipoprotein B 0.968341
CLPS colipase, pancreatic 0.913903
ALOX15B arachidonate 15-lipoxygenase, type B 0.902389
F10 coagulation factor X 0.86018
APOE apolipoprotein E 0.851992
APOA1 apolipoprotein A-I 0.837656
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.824128
FUBP3 far upstream element (FUSE) binding protein 3 0.812232
PON1 paraoxonase 1 0.805667
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.786803
DEGS2 delta(4)-desaturase, sphingolipid 2 0.785574
VWF von Willebrand factor 0.781479
AKR1D1 aldo-keto reductase family 1, member D1 0.772479
PCDHA10 protocadherin alpha 10 0.771252
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.744766
PON3 paraoxonase 3 0.736243
S100B S100 calcium binding protein B 0.722482
LDB1 LIM domain binding 1 0.718846
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.712392
ADGRL4 adhesion G protein-coupled receptor L4 0.709572
ACE angiotensin I converting enzyme 0.697109
MMP1 matrix metallopeptidase 1 0.695905
PTGES prostaglandin E synthase 0.695103
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.676706
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.669538
WDR20 WD repeat domain 20 0.657234
POLB polymerase (DNA directed), beta 0.633563
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.630813
AGTR2 angiotensin II receptor, type 2 0.630027
F2 coagulation factor II (thrombin) 0.630027
CD40LG CD40 ligand 0.626103
CD63 CD63 molecule 0.617094
SEC24B SEC24 family member B 0.608885
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.605762
THBD thrombomodulin 0.604201
FUT2 fucosyltransferase 2 (secretor status included) 0.60147
PTCH1 patched 1 0.595233
STXBP5 syntaxin binding protein 5 (tomosyn) 0.595233
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 0.594454
MMP2 matrix metallopeptidase 2 0.585497
AMH anti-Mullerian hormone 0.577327
COX5A cytochrome c oxidase subunit Va 0.571107
PON2 paraoxonase 2 0.570718
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.561781
SELE selectin E 0.554403
PLG plasminogen 0.550522
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.548971
TIMP1 TIMP metallopeptidase inhibitor 1 0.546644
VCAM1 vascular cell adhesion molecule 1 0.543155
MON2 MON2 homolog (S. cerevisiae) 0.540829
IL6 interleukin 6 0.540442
GLA galactosidase, alpha 0.537344
ICAM1 intercellular adhesion molecule 1 0.529994
CCL2 chemokine (C-C motif) ligand 2 0.528835
F5 coagulation factor V (proaccelerin, labile factor) 0.526518
C5ORF38 chromosome 5 open reading frame 38 0.522659
APOH apolipoprotein H (beta-2-glycoprotein I) 0.518034
GBP2 guanylate binding protein 2, interferon-inducible 0.517265
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.508808
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.508041
COG2 component of oligomeric golgi complex 2 0.503824
CD36 CD36 molecule (thrombospondin receptor) 0.499614
SPP1 secreted phosphoprotein 1 0.498849
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.495029
NOS3 nitric oxide synthase 3 (endothelial cell) 0.493885
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.493503
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.490835
LRP5 low density lipoprotein receptor-related protein 5 0.489691
KIF1BP KIF1 binding protein 0.479047
CROCC ciliary rootlet coiled-coil, rootletin 0.476393
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.474498
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.471089
NAMPT nicotinamide phosphoribosyltransferase 0.46655
ALB albumin 0.466172
CDC123 cell division cycle 123 0.463905
CBS cystathionine-beta-synthase 0.460883
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.457864
GPS1 G protein pathway suppressor 1 0.451831
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.446558
NPY5R neuropeptide Y receptor Y5 0.440162
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.437906
PSRC1 proline/serine-rich coiled-coil 1 0.436402
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.425514
COG1 component of oligomeric golgi complex 1 0.425139
SPAG1 sperm associated antigen 1 0.42214
SCARB2 scavenger receptor class B, member 2 0.42139
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.419892
SELENBP1 selenium binding protein 1 0.419142
PRCP prolylcarboxypeptidase (angiotensinase C) 0.41727
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.409787
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.405678
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.404184
KLHL21 kelch-like family member 21 0.393374
EFNA3 ephrin-A3 0.391141
PLA2G1B phospholipase A2, group IB (pancreas) 0.390025
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.382966
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.380368
S100A8 S100 calcium binding protein A8 0.379626
ARHGAP32 Rho GTPase activating protein 32 0.374438
PROCR protein C receptor, endothelial 0.368149
CD163 CD163 molecule 0.365932
SCARB1 scavenger receptor class B, member 1 0.365562
MAP6 microtubule-associated protein 6 0.36187
ARR3 arrestin 3, retinal (X-arrestin) 0.361133
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.355604
FAM131C family with sequence similarity 131, member C 0.354499
LPL lipoprotein lipase 0.352659
RER1 retention in endoplasmic reticulum sorting receptor 1 0.352291
NCR3 natural cytotoxicity triggering receptor 3 0.350084
MMP8 matrix metallopeptidase 8 0.349717
INS insulin 0.349349
SLC35E2B solute carrier family 35, member E2B 0.348981
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.348614
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.347511
GP6 glycoprotein VI (platelet) 0.346409
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.336876
AURKC aurora kinase C 0.332852
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.331391
POU2F3 POU class 2 homeobox 3 0.32993
FUCA1 fucosidase, alpha-L- 1, tissue 0.32774
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.324458
BMP6 bone morphogenetic protein 6 0.324094
NOTO notochord homeobox 0.32373
IL13RA1 interleukin 13 receptor, alpha 1 0.316819
BMP8B bone morphogenetic protein 8b 0.316819
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.312827
FOXO4 forkhead box O4 0.309566
HBA2 hemoglobin, alpha 2 0.309204
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 0.301976
CD79A CD79a molecule, immunoglobulin-associated alpha 0.298011
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.296931
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.295851
ENG endoglin 0.293694
TLN1 talin 1 0.292257
IGHV3-30 immunoglobulin heavy variable 3-30 0.287952
CPB2 carboxypeptidase B2 (plasma) 0.287235
FABP4 fatty acid binding protein 4, adipocyte 0.278297
STX4 syntaxin 4 0.277227
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.276514
VAV3 vav 3 guanine nucleotide exchange factor 0.271886
ZFHX3 zinc finger homeobox 3 0.271174
COL14A1 collagen, type XIV, alpha 1 0.271174
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.270819
S100A9 S100 calcium binding protein A9 0.269043
HBA1 hemoglobin, alpha 1 0.258064
ERCC6L excision repair cross-complementation group 6-like 0.257711
UST uronyl-2-sulfotransferase 0.257005
ZNF85 zinc finger protein 85 0.251366
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.251015
ADAM15 ADAM metallopeptidase domain 15 0.24996
NCF4 neutrophil cytosolic factor 4, 40kDa 0.249608
HPSE2 heparanase 2 (inactive) 0.245747
AANAT aralkylamine N-acetyltransferase 0.245747
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.245046
PRRC2A proline-rich coiled-coil 2A 0.240148
PALLD palladin, cytoskeletal associated protein 0.239799
IGLV5-52 immunoglobulin lambda variable 5-52 0.237706
MMD monocyte to macrophage differentiation-associated 0.237357
IGLV3-10 immunoglobulin lambda variable 3-10 0.234225
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.233183
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.230063
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.226952
MT2A metallothionein 2A 0.226607
MMP3 matrix metallopeptidase 3 0.224196
RBP4 retinol binding protein 4, plasma 0.223853
TSPAN8 tetraspanin 8 0.215992
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.211597
CREM cAMP responsive element modulator 0.210925
CD34 CD34 molecule 0.208579
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.206913
THEM5 thioesterase superfamily member 5 0.205916
ANXA5 annexin A5 0.203275
SPATA5 spermatogenesis associated 5 0.202946
KNG1 kininogen 1 0.199356
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.199033
CCR2 chemokine (C-C motif) receptor 2 0.199033
MON1A MON1 secretory trafficking family member A 0.198386
IL10RA interleukin 10 receptor, alpha 0.198064
FBL fibrillarin 0.19742
CIB1 calcium and integrin binding 1 (calmyrin) 0.197099
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.193285
LDLR low density lipoprotein receptor 0.192344
FABP2 fatty acid binding protein 2, intestinal 0.18651
RSPO1 R-spondin 1 0.185016
ADAM8 ADAM metallopeptidase domain 8 0.183541
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.182957
LPA lipoprotein, Lp(a) 0.177851
ALOX15 arachidonate 15-lipoxygenase 0.175411
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.174881
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.174617
LTA4H leukotriene A4 hydrolase 0.173571
IGLL5 immunoglobulin lambda-like polypeptide 5 0.172544
LIPG lipase, endothelial 0.170299
HSPA4 heat shock 70kDa protein 4 0.16933
PDGFB platelet-derived growth factor beta polypeptide 0.165435
S100A10 S100 calcium binding protein A10 0.165001
VIPR1 vasoactive intestinal peptide receptor 1 0.164571
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.163523
CRYBB2 crystallin, beta B2 0.163523
FYN FYN proto-oncogene, Src family tyrosine kinase 0.163111
CLDN11 claudin 11 0.161523
FBLL1 fibrillarin-like 1 0.159302
ACSL1 acyl-CoA synthetase long-chain family member 1 0.158605
GAA glucosidase, alpha; acid 0.14715
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.143012
LCK LCK proto-oncogene, Src family tyrosine kinase 0.142004
F2R coagulation factor II (thrombin) receptor 0.141102
APLP2 amyloid beta (A4) precursor-like protein 2 0.141055
BDKRB2 bradykinin receptor B2 0.140584
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.140405
AVP arginine vasopressin 0.139334
VAV1 vav 1 guanine nucleotide exchange factor 0.139158
MFGE8 milk fat globule-EGF factor 8 protein 0.13811
P4HB prolyl 4-hydroxylase, beta polypeptide 0.13779
NPPA natriuretic peptide A 0.137736
NOTCH1 notch 1 0.137498
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.137193
VASP vasodilator-stimulated phosphoprotein 0.136971
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.136391
SELPLG selectin P ligand 0.136144
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.133353
NOX4 NADPH oxidase 4 0.13176
CTSG cathepsin G 0.13176
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.131475
PDE4A phosphodiesterase 4A, cAMP-specific 0.131159
JAZF1 JAZF zinc finger 1 0.130834
MMP12 matrix metallopeptidase 12 0.130669
GPC3 glypican 3 0.130475
KMT2A lysine (K)-specific methyltransferase 2A 0.130304
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.130254
ERAS ES cell expressed Ras 0.130179
SKAP2 src kinase associated phosphoprotein 2 0.130054
ITLN1 intelectin 1 (galactofuranose binding) 0.129952
MPO myeloperoxidase 0.129823
LYN LYN proto-oncogene, Src family tyrosine kinase 0.129746
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.129323
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.129133
PER1 period circadian clock 1 0.129078
GREM2 gremlin 2, DAN family BMP antagonist 0.12863
ADAM9 ADAM metallopeptidase domain 9 0.128601
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.128545
MAP4 microtubule-associated protein 4 0.1284
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.127957
CRYGD crystallin, gamma D 0.127775
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.127745
IMMT inner membrane protein, mitochondrial 0.127248
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.127152
AHSG alpha-2-HS-glycoprotein 0.127152
JMJD6 jumonji domain containing 6 0.126991
ENO2 enolase 2 (gamma, neuronal) 0.126431