carisoprodol-6610 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the carisoprodol-6610 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM22 ADAM metallopeptidase domain 22
ADAP1 ArfGAP with dual PH domains 1
AGER advanced glycosylation end product-specific receptor
APOC4 apolipoprotein C-IV
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATXN3L ataxin 3-like
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BMP15 bone morphogenetic protein 15
BTF3P12 basic transcription factor 3 pseudogene 12
BTG2 BTG family, member 2
C8A complement component 8, alpha polypeptide
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CARD14 caspase recruitment domain family, member 14
CD27 CD27 molecule
CDK2 cyclin-dependent kinase 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL6A1 collagen, type VI, alpha 1
DAGLA diacylglycerol lipase, alpha
DCAF15 DDB1 and CUL4 associated factor 15
DDO D-aspartate oxidase
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
EDNRB endothelin receptor type B
EHD2 EH-domain containing 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ESR1 estrogen receptor 1
FAM163A family with sequence similarity 163, member A
FGF1 fibroblast growth factor 1 (acidic)
FMOD fibromodulin
FOXF1 forkhead box F1
FOXG1 forkhead box G1
FRMPD1 FERM and PDZ domain containing 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIPR gastric inhibitory polypeptide receptor
GNRHR gonadotropin-releasing hormone receptor
GRM8 glutamate receptor, metabotropic 8
HIST1H2BO histone cluster 1, H2bo
HOXA1 homeobox A1
HOXC10 homeobox C10
HPX hemopexin
IFNA2 interferon, alpha 2
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIDINS220 kinase D-interacting substrate, 220kDa
KLF1 Kruppel-like factor 1 (erythroid)
KLHL22 kelch-like family member 22
LINC00474 long intergenic non-protein coding RNA 474
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA5 melanoma antigen family A5
MAPK10 mitogen-activated protein kinase 10
MED25 mediator complex subunit 25
MUC6 mucin 6, oligomeric mucus/gel-forming
NEFM neurofilament, medium polypeptide
NOVA1 neuro-oncological ventral antigen 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCDHB17P protocadherin beta 17 pseudogene
PDE11A phosphodiesterase 11A
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF20 PHD finger protein 20
PPARD peroxisome proliferator-activated receptor delta
PTCRA pre T-cell antigen receptor alpha
PTEN phosphatase and tensin homolog
RAB40A RAB40A, member RAS oncogene family
RAI1 retinoic acid induced 1
RCE1 Ras converting CAAX endopeptidase 1
REEP2 receptor accessory protein 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RND1 Rho family GTPase 1
SCAPER S-phase cyclin A-associated protein in the ER
SCG2 secretogranin II
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
STC1 stanniocalcin 1
STMN4 stathmin-like 4
STS steroid sulfatase (microsomal), isozyme S
STXBP5L syntaxin binding protein 5-like
SVIL supervillin
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBCD tubulin folding cofactor D
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TLR2 toll-like receptor 2
TMPRSS4 transmembrane protease, serine 4
TNNT3 troponin T type 3 (skeletal, fast)
TRIM31 tripartite motif containing 31
ZNF24 zinc finger protein 24

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
AFAP1 actin filament associated protein 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASB7 ankyrin repeat and SOCS box containing 7
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHD1 bromo adjacent homology domain containing 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CENPQ centromere protein Q
CIDEB cell death-inducing DFFA-like effector b
CLSPN claspin
CNN2 calponin 2
CORO2A coronin, actin binding protein, 2A
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELP6 elongator acetyltransferase complex subunit 6
EN1 engrailed homeobox 1
ETNK2 ethanolamine kinase 2
EVPL envoplakin
FANCC Fanconi anemia, complementation group C
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4E histone cluster 1, H4e
HLX H2.0-like homeobox
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0753 KIAA0753
LOC100272216 uncharacterized LOC100272216
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEF1 melanoma antigen family F1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTD1 mbt domain containing 1
MED22 mediator complex subunit 22
MICALL2 MICAL-like 2
MTG1 mitochondrial ribosome-associated GTPase 1
NCOA2 nuclear receptor coactivator 2
NSUN6 NOP2/Sun domain family, member 6
NT5M 5',3'-nucleotidase, mitochondrial
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P3H2 prolyl 3-hydroxylase 2
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLXNB3 plexin B3
PPT2 palmitoyl-protein thioesterase 2
PRR7 proline rich 7 (synaptic)
PTDSS2 phosphatidylserine synthase 2
PTK7 protein tyrosine kinase 7 (inactive)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
S100A3 S100 calcium binding protein A3
SLC12A9 solute carrier family 12, member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SND1-IT1 SND1 intronic transcript 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM8A transmembrane protein 8A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBIAD1 UbiA prenyltransferase domain containing 1
USP19 ubiquitin specific peptidase 19
WDR18 WD repeat domain 18
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP30 ZFP30 zinc finger protein
ZNF214 zinc finger protein 214
ZNF264 zinc finger protein 264
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF510 zinc finger protein 510
ZNF551 zinc finger protein 551
ZNF652 zinc finger protein 652