carisoprodol-4955 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the carisoprodol-4955 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ADARB1 adenosine deaminase, RNA-specific, B1
AK1 adenylate kinase 1
AMH anti-Mullerian hormone
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPH aspartate beta-hydroxylase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2A1 BCL2-related protein A1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP4 bone morphogenetic protein 4
BTN2A2 butyrophilin, subfamily 2, member A2
C17ORF53 chromosome 17 open reading frame 53
C1QB complement component 1, q subcomponent, B chain
CABIN1 calcineurin binding protein 1
CACYBP calcyclin binding protein
CEP41 centrosomal protein 41kDa
CFAP69 cilia and flagella associated protein 69
CLCN7 chloride channel, voltage-sensitive 7
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CT62 cancer/testis antigen 62
CTSF cathepsin F
DEPDC5 DEP domain containing 5
DLK2 delta-like 2 homolog (Drosophila)
DMTN dematin actin binding protein
DUSP13 dual specificity phosphatase 13
EDAR ectodysplasin A receptor
EFCAB6 EF-hand calcium binding domain 6
ELK1 ELK1, member of ETS oncogene family
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPYC epiphycan
EXD3 exonuclease 3'-5' domain containing 3
FAM134B family with sequence similarity 134, member B
FBXO40 F-box protein 40
FLOT1 flotillin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAMT guanidinoacetate N-methyltransferase
GJB3 gap junction protein, beta 3, 31kDa
GMPR guanosine monophosphate reductase
GYG2 glycogenin 2
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOMER3 homer scaffolding protein 3
HP haptoglobin
ICA1 islet cell autoantigen 1, 69kDa
IDS iduronate 2-sulfatase
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
INA internexin neuronal intermediate filament protein, alpha
INO80D INO80 complex subunit D
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
KMT2A lysine (K)-specific methyltransferase 2A
KRT19P2 keratin 19 pseudogene 2
LBP lipopolysaccharide binding protein
LEPR leptin receptor
LPPR2 lipid phosphate phosphatase-related protein type 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MMP11 matrix metallopeptidase 11
MTCP1 mature T-cell proliferation 1
MYBPC3 myosin binding protein C, cardiac
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR0B2 nuclear receptor subfamily 0, group B, member 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCDHA5 protocadherin alpha 5
PDPN podoplanin
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PRDM12 PR domain containing 12
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
QPCTL glutaminyl-peptide cyclotransferase-like
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGS14 regulator of G-protein signaling 14
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPARCL1 SPARC-like 1 (hevin)
SRCAP Snf2-related CREBBP activator protein
SUGP1 SURP and G patch domain containing 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMPRSS2 transmembrane protease, serine 2
TOP3B topoisomerase (DNA) III beta
TPMT thiopurine S-methyltransferase
TTC9 tetratricopeptide repeat domain 9
UNC93B1 unc-93 homolog B1 (C. elegans)
WSB1 WD repeat and SOCS box containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZNF137P zinc finger protein 137, pseudogene
ZNF177 zinc finger protein 177
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ACVR2A activin A receptor, type IIA
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX2 armadillo repeat containing, X-linked 2
AXIN1 axin 1
C17ORF70 chromosome 17 open reading frame 70
CCDC121 coiled-coil domain containing 121
CDKL3 cyclin-dependent kinase-like 3
CENPQ centromere protein Q
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCF1 cardiotrophin-like cytokine factor 1
CST6 cystatin E/M
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM127B family with sequence similarity 127, member B
FAM189A2 family with sequence similarity 189, member A2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXO31 F-box protein 31
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPATCH3 G patch domain containing 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMBOX1 homeobox containing 1
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFLR1 IGF-like family receptor 1
IRF2 interferon regulatory factor 2
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KCTD20 potassium channel tetramerization domain containing 20
KIAA0754 KIAA0754
LHX6 LIM homeobox 6
LMNB1 lamin B1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC8E leucine rich repeat containing 8 family, member E
MB myoglobin
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFSD11 major facilitator superfamily domain containing 11
MOGS mannosyl-oligosaccharide glucosidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PAGR1 PAXIP1 associated glutamate-rich protein 1
PELI1 pellino E3 ubiquitin protein ligase 1
PGP phosphoglycolate phosphatase
PITX2 paired-like homeodomain 2
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PRPH peripherin
RPGRIP1L RPGRIP1-like
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A4 S100 calcium binding protein A4
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD1A SET domain containing 1A
SHARPIN SHANK-associated RH domain interactor
SIX1 SIX homeobox 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TMOD3 tropomodulin 3 (ubiquitous)
TPCN1 two pore segment channel 1
TRAPPC13 trafficking protein particle complex 13
TUBA3C tubulin, alpha 3c
WDR25 WD repeat domain 25
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF329 zinc finger protein 329
ZNF37BP zinc finger protein 37B, pseudogene
ZNF586 zinc finger protein 586
ZNF668 zinc finger protein 668
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862