card domain binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family. (Gene Ontology, GO_0050700)
External Link http://amigo.geneontology.org/amigo/term/GO:0050700
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Genes

8 genes performing the card domain binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
C9ORF89 chromosome 9 open reading frame 89
CARD11 caspase recruitment domain family, member 11
CARD14 caspase recruitment domain family, member 14
CARD9 caspase recruitment domain family, member 9
MAVS mitochondrial antiviral signaling protein
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
RIPK2 receptor-interacting serine-threonine kinase 2