carboxy-terminal domain protein kinase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5. (Gene Ontology, GO_0032806)
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Genes

163 proteins co-occuring with the carboxy-terminal domain protein kinase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDK9 cyclin-dependent kinase 9 3.5527
CCNT1 cyclin T1 3.32881
HEXIM1 hexamethylene bis-acetamide inducible 1 2.7947
BRD4 bromodomain containing 4 2.08526
TAT tyrosine aminotransferase 1.92577
CDK7 cyclin-dependent kinase 7 1.80106
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.78255
AFF4 AF4/FMR2 family, member 4 1.75147
CCNT2 cyclin T2 1.74892
LARP7 La ribonucleoprotein domain family, member 7 1.72119
HEXIM2 hexamethylene bis-acetamide inducible 2 1.67325
CCNK cyclin K 1.66296
JAG2 jagged 2 1.63539
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.46608
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 1.35649
MEPCE methylphosphate capping enzyme 1.35156
ERCC2 excision repair cross-complementation group 2 1.32817
ELL2 elongation factor, RNA polymerase II, 2 1.29799
ELL elongation factor RNA polymerase II 1.27027
AFF1 AF4/FMR2 family, member 1 1.23192
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.21583
AFF3 AF4/FMR2 family, member 3 0.928422
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.917177
ZNF512 zinc finger protein 512 0.907855
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.903673
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.902281
CDK8 cyclin-dependent kinase 8 0.86123
CCNH cyclin H 0.829089
GTF2H5 general transcription factor IIH, polypeptide 5 0.81624
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.813487
BRD2 bromodomain containing 2 0.801562
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.742318
DOT1L DOT1-like histone H3K79 methyltransferase 0.740515
CDK12 cyclin-dependent kinase 12 0.728836
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.725705
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.711465
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.702185
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.67246
CIITA class II, major histocompatibility complex, transactivator 0.659482
H3F3A H3 histone, family 3A 0.656895
H3F3B H3 histone, family 3B (H3.3B) 0.656895
KAT2B K(lysine) acetyltransferase 2B 0.654311
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.65259
HMGA1 high mobility group AT-hook 1 0.633732
PPP1R10P1 protein phosphatase 1, regulatory subunit 10 pseudogene 1 0.621379
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.601487
MED26 mediator complex subunit 26 0.597276
ERCC5 excision repair cross-complementation group 5 0.585105
AFF2 AF4/FMR2 family, member 2 0.584268
CD4 CD4 molecule 0.578833
ELL3 elongation factor RNA polymerase II-like 3 0.569248
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.543176
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.484079
BRDT bromodomain, testis-specific 0.483273
HSPA4 heat shock 70kDa protein 4 0.476027
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.463598
SNW1 SNW domain containing 1 0.456012
TOX3 TOX high mobility group box family member 3 0.438542
GTF2B general transcription factor IIB 0.431041
IWS1 IWS1 homolog (S. cerevisiae) 0.430647
HIST3H2BB histone cluster 3, H2bb 0.422782
HIST2H2BF histone cluster 2, H2bf 0.422782
HIST1H2BH histone cluster 1, H2bh 0.422782
HIST1H2BD histone cluster 1, H2bd 0.422389
HIST1H2BC histone cluster 1, H2bc 0.42082
HIST1H2BF histone cluster 1, H2bf 0.42082
HIST1H2BA histone cluster 1, H2ba 0.420036
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.41143
MDFI MyoD family inhibitor 0.411039
HIST2H4A histone cluster 2, H4a 0.407919
HIST2H4B histone cluster 2, H4b 0.407919
HIST1H4F histone cluster 1, H4f 0.407919
HIST1H4B histone cluster 1, H4b 0.407919
HIST1H4C histone cluster 1, H4c 0.407919
HIST1H4A histone cluster 1, H4a 0.407919
HIST1H4H histone cluster 1, H4h 0.407919
HIST1H4I histone cluster 1, H4i 0.407919
HIST1H4D histone cluster 1, H4d 0.407919
HIST1H4E histone cluster 1, H4e 0.407919
HIST1H4J histone cluster 1, H4j 0.407919
HIST1H4K histone cluster 1, H4k 0.407919
HIST1H4L histone cluster 1, H4l 0.407529
HIST4H4 histone cluster 4, H4 0.407529
AIRE autoimmune regulator 0.381584
CDC37 cell division cycle 37 0.381584
HIC2 hypermethylated in cancer 2 0.381199
BRD3 bromodomain containing 3 0.381199
PRDM14 PR domain containing 14 0.37505
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.371982
SETD2 SET domain containing 2 0.370067
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.366623
GRN granulin 0.364331
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.356324
CDK2 cyclin-dependent kinase 2 0.355944
DEFA1B defensin, alpha 1B 0.340395
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.333602
TEF thyrotrophic embryonic factor 0.329837
DEFA1 defensin, alpha 1 0.326078
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.324951
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.3227
SP3 Sp3 transcription factor 0.322325
RUNX1 runt-related transcription factor 1 0.314091
LMO2 LIM domain only 2 (rhombotin-like 1) 0.313718
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.310732
NELFA negative elongation factor complex member A 0.303655
CDK4 cyclin-dependent kinase 4 0.303655
SKI SKI proto-oncogene 0.296972
FBXO11 F-box protein 11 0.284401
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.281821
TP53 tumor protein p53 0.280716
CDK13 cyclin-dependent kinase 13 0.277774
RBM23 RNA binding motif protein 23 0.273734
ILF3 interleukin enhancer binding factor 3, 90kDa 0.273
EEF1G eukaryotic translation elongation factor 1 gamma 0.271167
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.270434
JMJD6 jumonji domain containing 6 0.267871
TBP TATA box binding protein 0.256197
SMYD3 SET and MYND domain containing 3 0.250751
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.248216
MC5R melanocortin 5 receptor 0.24424
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.230958
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.230601
MYOD1 myogenic differentiation 1 0.224204
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.221025
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.220673
WDR82 WD repeat domain 82 0.217861
CBX8 chromobox homolog 8 0.21646
HIPK3 homeodomain interacting protein kinase 3 0.209858
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.209858
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.204039
HSF1 heat shock transcription factor 1 0.202009
FOS FBJ murine osteosarcoma viral oncogene homolog 0.201672
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.194698
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 0.191456
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.189539
BCOR BCL6 corepressor 0.18796
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.18702
KMT2A lysine (K)-specific methyltransferase 2A 0.180045
MED23 mediator complex subunit 23 0.179167
NUTM1 NUT midline carcinoma, family member 1 0.176305
KIAA0101 KIAA0101 0.172468
CCNC cyclin C 0.146999
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 0.143218
SETD1A SET domain containing 1A 0.138551
ELP3 elongator acetyltransferase complex subunit 3 0.137073
KLF9 Kruppel-like factor 9 0.136194
NUP133 nucleoporin 133kDa 0.135686
RARG retinoic acid receptor, gamma 0.1343
PYCR1 pyrroline-5-carboxylate reductase 1 0.132669
SLK STE20-like kinase 0.131157
MTA1 metastasis associated 1 0.129417
MATK megakaryocyte-associated tyrosine kinase 0.12732
JUND jun D proto-oncogene 0.126198
POLI polymerase (DNA directed) iota 0.125766
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.125098
IMMT inner membrane protein, mitochondrial 0.124643
HDAC2 histone deacetylase 2 0.123347
CNTLN centlein, centrosomal protein 0.121706
RARS arginyl-tRNA synthetase 0.118196
MCM7 minichromosome maintenance complex component 7 0.117438
BRCA1 breast cancer 1, early onset 0.115147
WRNIP1 Werner helicase interacting protein 1 0.113029
FOXC2 forkhead box C2 0.112915