carbinoxamine-7138 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the carbinoxamine-7138 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACSL5 acyl-CoA synthetase long-chain family member 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BIN1 bridging integrator 1
C14ORF1 chromosome 14 open reading frame 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA5B carbonic anhydrase VB, mitochondrial
CCP110 centriolar coiled coil protein 110kDa
CDK6 cyclin-dependent kinase 6
CEP70 centrosomal protein 70kDa
CFAP69 cilia and flagella associated protein 69
CLN3 ceroid-lipofuscinosis, neuronal 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COQ6 coenzyme Q6 monooxygenase
CREM cAMP responsive element modulator
CRTC1 CREB regulated transcription coactivator 1
DCAF17 DDB1 and CUL4 associated factor 17
DOPEY1 dopey family member 1
DUSP3 dual specificity phosphatase 3
DZIP1 DAZ interacting zinc finger protein 1
EFNA3 ephrin-A3
EPHB2 EPH receptor B2
FAM214B family with sequence similarity 214, member B
FKBP5 FK506 binding protein 5
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR107 G protein-coupled receptor 107
GPR25 G protein-coupled receptor 25
HCRP1 hepatocellular carcinoma-related HCRP1
HOMER3 homer scaffolding protein 3
HOXC5 homeobox C5
HPS1 Hermansky-Pudlak syndrome 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
KLF6 Kruppel-like factor 6
KRT15 keratin 15, type I
LHX2 LIM homeobox 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPK7 mitogen-activated protein kinase 7
MAST3 microtubule associated serine/threonine kinase 3
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFN2 mitofusin 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MTUS1 microtubule associated tumor suppressor 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
PCDHGA3 protocadherin gamma subfamily A, 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PEX7 peroxisomal biogenesis factor 7
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX1 paired-like homeodomain 1
PLCD1 phospholipase C, delta 1
PLK4 polo-like kinase 4
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPT2 palmitoyl-protein thioesterase 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB31 RAB31, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RANBP3 RAN binding protein 3
RARA retinoic acid receptor, alpha
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RERE arginine-glutamic acid dipeptide (RE) repeats
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SCAMP5 secretory carrier membrane protein 5
SCARB1 scavenger receptor class B, member 1
SECISBP2 SECIS binding protein 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPATA2L spermatogenesis associated 2-like
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSH3 slingshot protein phosphatase 3
STK16 serine/threonine kinase 16
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TELO2 telomere maintenance 2
TH tyrosine hydroxylase
TRIM25 tripartite motif containing 25
TTC38 tetratricopeptide repeat domain 38
UBE3A ubiquitin protein ligase E3A
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XYLB xylulokinase homolog (H. influenzae)
ZFHX3 zinc finger homeobox 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF174 zinc finger protein 174
ZNF202 zinc finger protein 202

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACTN4 actinin, alpha 4
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANOS1 anosmin 1
ARSJ arylsulfatase family, member J
BBS4 Bardet-Biedl syndrome 4
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
C10ORF2 chromosome 10 open reading frame 2
C2ORF44 chromosome 2 open reading frame 44
CAMTA2 calmodulin binding transcription activator 2
CCDC69 coiled-coil domain containing 69
CCDC91 coiled-coil domain containing 91
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CPQ carboxypeptidase Q
CXORF56 chromosome X open reading frame 56
DCAF4 DDB1 and CUL4 associated factor 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND4B DENN/MADD domain containing 4B
EFTUD1 elongation factor Tu GTP binding domain containing 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
FAM53C family with sequence similarity 53, member C
FAM86C1 family with sequence similarity 86, member C1
FBXO46 F-box protein 46
FGD1 FYVE, RhoGEF and PH domain containing 1
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP14 FK506 binding protein 14, 22 kDa
FOXJ2 forkhead box J2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS6 HAUS augmin-like complex, subunit 6
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HOXC10 homeobox C10
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
INCENP inner centromere protein antigens 135/155kDa
KIAA0355 KIAA0355
KIAA0894 KIAA0894 protein
KLHL21 kelch-like family member 21
L2HGDH L-2-hydroxyglutarate dehydrogenase
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR3 lysophosphatidic acid receptor 3
METTL8 methyltransferase like 8
MGC12488
MMP1 matrix metallopeptidase 1
MON1B MON1 secretory trafficking family member B
MYLK myosin light chain kinase
OSTF1 osteoclast stimulating factor 1
OTUD3 OTU deubiquitinase 3
PARD6A par-6 family cell polarity regulator alpha
PMPCA peptidase (mitochondrial processing) alpha
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTBP2 polypyrimidine tract binding protein 2
RAB3A RAB3A, member RAS oncogene family
RANBP17 RAN binding protein 17
REPIN1 replication initiator 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB1 Rho-related BTB domain containing 1
RNF220 ring finger protein 220
ROGDI rogdi homolog (Drosophila)
SCRN3 secernin 3
SETD1B SET domain containing 1B
SGMS1 sphingomyelin synthase 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG20 small nucleolar RNA host gene 20
SPAG1 sperm associated antigen 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STARD13 StAR-related lipid transfer (START) domain containing 13
SUGCT succinyl-CoA:glutarate-CoA transferase
SUOX sulfite oxidase
TBC1D10B TBC1 domain family, member 10B
TCTA T-cell leukemia translocation altered
TESK1 testis-specific kinase 1
TGFB3 transforming growth factor, beta 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM57 transmembrane protein 57
TRAPPC11 trafficking protein particle complex 11
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
TULP4 tubby like protein 4
UBL4A ubiquitin-like 4A
WDR19 WD repeat domain 19
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC24 zinc finger, DHHC-type containing 24
ZFP36 ZFP36 ring finger protein
ZNF112 zinc finger protein 112
ZNF227 zinc finger protein 227
ZNF443 zinc finger protein 443