carbinoxamine-6786 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the carbinoxamine-6786 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF3 AF4/FMR2 family, member 3
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX15 arachidonate 15-lipoxygenase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BBS9 Bardet-Biedl syndrome 9
C19ORF66 chromosome 19 open reading frame 66
CA4 carbonic anhydrase IV
CDK14 cyclin-dependent kinase 14
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CLCN4 chloride channel, voltage-sensitive 4
COL6A1 collagen, type VI, alpha 1
CRLF2 cytokine receptor-like factor 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DTNA dystrobrevin, alpha
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EHBP1L1 EH domain binding protein 1-like 1
EMID1 EMI domain containing 1
FGF18 fibroblast growth factor 18
FGF3 fibroblast growth factor 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXI1 forkhead box I1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1T histone cluster 1, H1t
HLF hepatic leukemia factor
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFNA14 interferon, alpha 14
IL6R interleukin 6 receptor
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL3 muscleblind-like splicing regulator 3
MTSS1L metastasis suppressor 1-like
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF1 neurofibromin 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOL12 nucleolar protein 12
NPY neuropeptide Y
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAIP2B poly(A) binding protein interacting protein 2B
PDLIM5 PDZ and LIM domain 5
PGAP1 post-GPI attachment to proteins 1
PLEC plectin
PLIN2 perilipin 2
PLXND1 plexin D1
PML promyelocytic leukemia
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRPH2 peripherin 2 (retinal degeneration, slow)
PTRF polymerase I and transcript release factor
RAD51 RAD51 recombinase
RASAL2 RAS protein activator like 2
RER1 retention in endoplasmic reticulum sorting receptor 1
RIMS2 regulating synaptic membrane exocytosis 2
RND2 Rho family GTPase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SIRT5 sirtuin 5
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOX9 SRY (sex determining region Y)-box 9
SPTBN1 spectrin, beta, non-erythrocytic 1
SSPN sarcospan
STAT5B signal transducer and activator of transcription 5B
SURF1 surfeit 1
TAOK2 TAO kinase 2
TDRKH tudor and KH domain containing
TLR2 toll-like receptor 2
TNK2 tyrosine kinase, non-receptor, 2
TOP3B topoisomerase (DNA) III beta
TP53I11 tumor protein p53 inducible protein 11
TPM3 tropomyosin 3
TPSG1 tryptase gamma 1
TSC22D2 TSC22 domain family, member 2
VLDLR very low density lipoprotein receptor
VWA5A von Willebrand factor A domain containing 5A
WDR62 WD repeat domain 62
WDTC1 WD and tetratricopeptide repeats 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF350 zinc finger protein 350
ZNF571 zinc finger protein 571
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSF2 acyl-CoA synthetase family member 2
ALDOC aldolase C, fructose-bisphosphate
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
AUH AU RNA binding protein/enoyl-CoA hydratase
AUTS2 autism susceptibility candidate 2
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF30 chromosome 11 open reading frame 30
CBR4 carbonyl reductase 4
CCDC121 coiled-coil domain containing 121
CCDC134 coiled-coil domain containing 134
CCDC25 coiled-coil domain containing 25
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CORO7 coronin 7
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DMTF1 cyclin D binding myb-like transcription factor 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECH1 enoyl CoA hydratase 1, peroxisomal
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELMO3 engulfment and cell motility 3
FAM189A2 family with sequence similarity 189, member A2
FBXL2 F-box and leucine-rich repeat protein 2
FBXO22 F-box protein 22
FRS2 fibroblast growth factor receptor substrate 2
GATA4 GATA binding protein 4
GDAP1 ganglioside induced differentiation associated protein 1
GLB1L2 galactosidase, beta 1-like 2
GLRX glutaredoxin (thioltransferase)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL1 guanine nucleotide binding protein-like 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HDAC7 histone deacetylase 7
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HLA-DMA major histocompatibility complex, class II, DM alpha
IDI2-AS1 IDI2 antisense RNA 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
LIN7B lin-7 homolog B (C. elegans)
LOC730101 uncharacterized LOC730101
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN2C1 mannosidase, alpha, class 2C, member 1
MFAP2 microfibrillar-associated protein 2
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
NME5 NME/NM23 family member 5
ONECUT2 one cut homeobox 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDH12 protocadherin 12
PDE12 phosphodiesterase 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PICK1 protein interacting with PRKCA 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLXNA3 plexin A3
PRF1 perforin 1 (pore forming protein)
PRICKLE3 prickle homolog 3 (Drosophila)
RFXAP regulatory factor X-associated protein
RGS2 regulator of G-protein signaling 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCAI suppressor of cancer cell invasion
SDC3 syndecan 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A9 solute carrier family 12, member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STMN3 stathmin-like 3
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCHH trichohyalin
TDP1 tyrosyl-DNA phosphodiesterase 1
TPST1 tyrosylprotein sulfotransferase 1
TRAF2 TNF receptor-associated factor 2
TRIM5 tripartite motif containing 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
WDR91 WD repeat domain 91
ZFHX3 zinc finger homeobox 3
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747