carbinoxamine-2725 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the carbinoxamine-2725 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADGRB1 adhesion G protein-coupled receptor B1
AEN apoptosis enhancing nuclease
AFF4 AF4/FMR2 family, member 4
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID4B AT rich interactive domain 4B (RBP1-like)
BAIAP2 BAI1-associated protein 2
BAZ2B bromodomain adjacent to zinc finger domain, 2B
CD36 CD36 molecule (thrombospondin receptor)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEP41 centrosomal protein 41kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLTA clathrin, light chain A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CTRB2 chymotrypsinogen B2
DLC1 DLC1 Rho GTPase activating protein
DMRT1 doublesex and mab-3 related transcription factor 1
DRD2 dopamine receptor D2
EPHA1 EPH receptor A1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO4 F-box protein 4
FCMR Fc fragment of IgM receptor
FGD2 FYVE, RhoGEF and PH domain containing 2
FGFR1 fibroblast growth factor receptor 1
FLOT1 flotillin 1
FMO5 flavin containing monooxygenase 5
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GALC galactosylceramidase
GCKR glucokinase (hexokinase 4) regulator
GLI3 GLI family zinc finger 3
GPR182 G protein-coupled receptor 182
GPX5 glutathione peroxidase 5
GRM7 glutamate receptor, metabotropic 7
HIST1H4E histone cluster 1, H4e
HLA-F major histocompatibility complex, class I, F
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA4 homeobox A4
HOXC11 homeobox C11
HPD 4-hydroxyphenylpyruvate dioxygenase
HRH3 histamine receptor H3
IL3RA interleukin 3 receptor, alpha (low affinity)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIF13A kinesin family member 13A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL3 kelch-like family member 3
KRT1 keratin 1, type II
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LY6G6D lymphocyte antigen 6 complex, locus G6D
MAU2 MAU2 sister chromatid cohesion factor
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFSD6 major facilitator superfamily domain containing 6
MMP25 matrix metallopeptidase 25
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NAP1L2 nucleosome assembly protein 1-like 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NXN nucleoredoxin
OPCML opioid binding protein/cell adhesion molecule-like
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLK4 polo-like kinase 4
PLXNC1 plexin C1
PPAP2B phosphatidic acid phosphatase type 2B
PRMT8 protein arginine methyltransferase 8
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PVR poliovirus receptor
QSER1 glutamine and serine rich 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM12B RNA binding motif protein 12B
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SCAMP5 secretory carrier membrane protein 5
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYNDIG1 synapse differentiation inducing 1
SYNM synemin, intermediate filament protein
TBKBP1 TBK1 binding protein 1
TEF thyrotrophic embryonic factor
TEX15 testis expressed 15
TGFB2 transforming growth factor, beta 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM3 tripartite motif containing 3
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TUBA8 tubulin, alpha 8
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZBTB38 zinc finger and BTB domain containing 38
ZNF132 zinc finger protein 132
ZNF710 zinc finger protein 710
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARMCX4 armadillo repeat containing, X-linked 4
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C5AR1 complement component 5a receptor 1
CCDC176 coiled-coil domain containing 176
CCDC57 coiled-coil domain containing 57
CCRL2 chemokine (C-C motif) receptor-like 2
CEP295 centrosomal protein 295kDa
CES3 carboxylesterase 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COPS7B COP9 signalosome subunit 7B
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CTSV cathepsin V
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB6 EPH receptor B6
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPC3 glypican 3
GPR75 G protein-coupled receptor 75
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRIP2 glutamate receptor interacting protein 2
GSTT1 glutathione S-transferase theta 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AE histone cluster 1, H2ae
HYAL3 hyaluronoglucosaminidase 3
IGSF6 immunoglobulin superfamily, member 6
INO80D INO80 complex subunit D
IQCG IQ motif containing G
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA1107 KIAA1107
KPNA5 karyopherin alpha 5 (importin alpha 6)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIN7B lin-7 homolog B (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LOC729164 hCG1732469
MEP1B meprin A, beta
MFSD11 major facilitator superfamily domain containing 11
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTSS1L metastasis suppressor 1-like
MVP major vault protein
MYL5 myosin, light chain 5, regulatory
MYOZ3 myozenin 3
NAG18 NAG18 mRNA
NECAB3 N-terminal EF-hand calcium binding protein 3
NME8 NME/NM23 family member 8
NNAT neuronatin
OLAH oleoyl-ACP hydrolase
OXCT2 3-oxoacid CoA transferase 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAQR4 progestin and adipoQ receptor family member IV
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZD7 PDZ domain containing 7
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMFBP1 polyamine modulated factor 1 binding protein 1
PNMA1 paraneoplastic Ma antigen 1
POLL polymerase (DNA directed), lambda
PRF1 perforin 1 (pore forming protein)
PRR14L proline rich 14-like
PYGB phosphorylase, glycogen; brain
RAB13 RAB13, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RCAN3 RCAN family member 3
RETN resistin
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SIRT6 sirtuin 6
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMA4 glucuronidase, beta pseudogene
SPATA1 spermatogenesis associated 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SV2A synaptic vesicle glycoprotein 2A
TCTN2 tectonic family member 2
TEAD3 TEA domain family member 3
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TUBB2A tubulin, beta 2A class IIa
UNC119 unc-119 homolog (C. elegans)
UPP1 uridine phosphorylase 1
USP6NL USP6 N-terminal like
VASH1 vasohibin 1
XYLT2 xylosyltransferase II
ZNF345 zinc finger protein 345