carbimazole-2437 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the carbimazole-2437 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AIM1L absent in melanoma 1-like
AIRE autoimmune regulator
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ANGPT1 angiopoietin 1
APLP2 amyloid beta (A4) precursor-like protein 2
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BGN biglycan
BTD biotinidase
CCDC85B coiled-coil domain containing 85B
CCR8 chemokine (C-C motif) receptor 8
CD6 CD6 molecule
CDRT1 CMT1A duplicated region transcript 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CREBZF CREB/ATF bZIP transcription factor
CRTAC1 cartilage acidic protein 1
CSF1 colony stimulating factor 1 (macrophage)
CTRL chymotrypsin-like
CTTN cortactin
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DLC1 DLC1 Rho GTPase activating protein
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF1 eukaryotic translation initiation factor 1
ERCC6L excision repair cross-complementation group 6-like
FAM105A family with sequence similarity 105, member A
FBXL7 F-box and leucine-rich repeat protein 7
FCMR Fc fragment of IgM receptor
FKRP fukutin related protein
FZD6 frizzled class receptor 6
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GSK3A glycogen synthase kinase 3 alpha
HIST1H2BC histone cluster 1, H2bc
HN1L hematological and neurological expressed 1-like
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICOSLG inducible T-cell co-stimulator ligand
IGLJ3 immunoglobulin lambda joining 3
IL5RA interleukin 5 receptor, alpha
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LHX1 LIM homeobox 1
LRRC41 leucine rich repeat containing 41
MAK male germ cell-associated kinase
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCL1 myeloid cell leukemia 1
MNX1 motor neuron and pancreas homeobox 1
MTCL1 microtubule crosslinking factor 1
MTSS1 metastasis suppressor 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEBL nebulette
NEK9 NIMA-related kinase 9
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NUP54 nucleoporin 54kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PARVB parvin, beta
PAX3 paired box 3
PCDHGB5 protocadherin gamma subfamily B, 5
PIWIL1 piwi-like RNA-mediated gene silencing 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLSCR3 phospholipid scramblase 3
POU2F2 POU class 2 homeobox 2
PQLC2 PQ loop repeat containing 2
PRAMEF11 PRAME family member 11
PRB4 proline-rich protein BstNI subfamily 4
RAB35 RAB35, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RYR2 ryanodine receptor 2 (cardiac)
SLC17A2 solute carrier family 17, member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A14 solute carrier family 22, member 14
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SNW1 SNW domain containing 1
SP1 Sp1 transcription factor
SPRED2 sprouty-related, EVH1 domain containing 2
SPTBN2 spectrin, beta, non-erythrocytic 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
TAT tyrosine aminotransferase
TBCD tubulin folding cofactor D
THRB thyroid hormone receptor, beta
THSD7A thrombospondin, type I, domain containing 7A
TM4SF5 transmembrane 4 L six family member 5
TRIM25 tripartite motif containing 25
WDR25 WD repeat domain 25
WWC1 WW and C2 domain containing 1
XDH xanthine dehydrogenase
YY1 YY1 transcription factor
ZER1 zyg-11 related, cell cycle regulator
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF154 zinc finger protein 154
ZNF675 zinc finger protein 675
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BANK1 B-cell scaffold protein with ankyrin repeats 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C9ORF9 chromosome 9 open reading frame 9
CARF calcium responsive transcription factor
CBX7 chromobox homolog 7
CENPB centromere protein B, 80kDa
CENPT centromere protein T
CEP131 centrosomal protein 131kDa
CHMP6 charged multivesicular body protein 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COQ6 coenzyme Q6 monooxygenase
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
DGKG diacylglycerol kinase, gamma 90kDa
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EDAR ectodysplasin A receptor
EMID1 EMI domain containing 1
EMILIN2 elastin microfibril interfacer 2
EXOSC1 exosome component 1
FAM86B1 family with sequence similarity 86, member B1
FLT4 fms-related tyrosine kinase 4
GAA glucosidase, alpha; acid
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA6 GATA binding protein 6
HDAC7 histone deacetylase 7
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IL3RA interleukin 3 receptor, alpha (low affinity)
INHBA inhibin, beta A
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KLHL36 kelch-like family member 36
LGALS4 lectin, galactoside-binding, soluble, 4
LIME1 Lck interacting transmembrane adaptor 1
LRRC20 leucine rich repeat containing 20
LTBP3 latent transforming growth factor beta binding protein 3
LTC4S leukotriene C4 synthase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MIR22HG MIR22 host gene
MRAS muscle RAS oncogene homolog
MYH15 myosin, heavy chain 15
NCKAP1L NCK-associated protein 1-like
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OXCT2 3-oxoacid CoA transferase 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PADI1 peptidyl arginine deiminase, type I
PARP3 poly (ADP-ribose) polymerase family, member 3
PDGFD platelet derived growth factor D
PER3 period circadian clock 3
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRR14L proline rich 14-like
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTCD1 pentatricopeptide repeat domain 1
RHOBTB1 Rho-related BTB domain containing 1
RUSC2 RUN and SH3 domain containing 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2D4A SH2 domain containing 4A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNAI1 snail family zinc finger 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA20 spermatogenesis associated 20
SPRR2B small proline-rich protein 2B
STX11 syntaxin 11
TAGLN transgelin
TIMP2 TIMP metallopeptidase inhibitor 2
TMC5 transmembrane channel-like 5
TMEM254 transmembrane protein 254
TRAF1 TNF receptor-associated factor 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VEGFC vascular endothelial growth factor C
VEZT vezatin, adherens junctions transmembrane protein
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
YPEL1 yippee-like 1 (Drosophila)
ZBED8 zinc finger, BED-type containing 8
ZC3H12A zinc finger CCCH-type containing 12A
ZNF862 zinc finger protein 862