carbamazepine-952 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the carbamazepine-952 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AKAP17A A kinase (PRKA) anchor protein 17A
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOE apolipoprotein E
ATF3 activating transcription factor 3
BTN2A2 butyrophilin, subfamily 2, member A2
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CACYBP calcyclin binding protein
CDK13 cyclin-dependent kinase 13
CES3 carboxylesterase 3
CLCN7 chloride channel, voltage-sensitive 7
CSRP2 cysteine and glycine-rich protein 2
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DBT dihydrolipoamide branched chain transacylase E2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIAPH1 diaphanous-related formin 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAN1 FANCD2/FANCI-associated nuclease 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FZD1 frizzled class receptor 1
GEM GTP binding protein overexpressed in skeletal muscle
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GON4L gon-4-like (C. elegans)
GSTM4 glutathione S-transferase mu 4
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IQCK IQ motif containing K
ITFG2 integrin alpha FG-GAP repeat containing 2
JUN jun proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
KLHL24 kelch-like family member 24
LMF2 lipase maturation factor 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MBD1 methyl-CpG binding domain protein 1
MED6 mediator complex subunit 6
MMP19 matrix metallopeptidase 19
MX2 MX dynamin-like GTPase 2
MYCNOS MYCN opposite strand
NAIP NLR family, apoptosis inhibitory protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAPOLA poly(A) polymerase alpha
PAX9 paired box 9
PCDH9 protocadherin 9
PER1 period circadian clock 1
PEX26 peroxisomal biogenesis factor 26
PGAP1 post-GPI attachment to proteins 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPARA peroxisome proliferator-activated receptor alpha
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRSS16 protease, serine, 16 (thymus)
PTCH1 patched 1
PVT1 Pvt1 oncogene (non-protein coding)
RAB3A RAB3A, member RAS oncogene family
RBM19 RNA binding motif protein 19
RGS2 regulator of G-protein signaling 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX13 SRY (sex determining region Y)-box 13
SOX4 SRY (sex determining region Y)-box 4
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRRM2 serine/arginine repetitive matrix 2
STX2 syntaxin 2
SYMPK symplekin
SYNGR1 synaptogyrin 1
TCP11L1 t-complex 11, testis-specific-like 1
THBD thrombomodulin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
TRIM52 tripartite motif containing 52
TSC22D2 TSC22 domain family, member 2
UBOX5 U-box domain containing 5
VIPR1 vasoactive intestinal peptide receptor 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF606 zinc finger protein 606
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP2 acylphosphatase 2, muscle type
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMC6 armadillo repeat containing 6
BARD1 BRCA1 associated RING domain 1
C11ORF95 chromosome 11 open reading frame 95
CBX4 chromobox homolog 4
CCNE2 cyclin E2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPC centromere protein C
CLK4 CDC-like kinase 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTC1 CTS telomere maintenance complex component 1
DESI1 desumoylating isopeptidase 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAL4 dynein, axonemal, light chain 4
ECHDC2 enoyl CoA hydratase domain containing 2
EFCAB2 EF-hand calcium binding domain 2
EGR3 early growth response 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF5A2 eukaryotic translation initiation factor 5A2
EXOC5 exocyst complex component 5
FAR2 fatty acyl CoA reductase 2
FBXL4 F-box and leucine-rich repeat protein 4
FMO4 flavin containing monooxygenase 4
FNTB farnesyltransferase, CAAX box, beta
FOXC1 forkhead box C1
FPGS folylpolyglutamate synthase
GLMN glomulin, FKBP associated protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPALPP1 GPALPP motifs containing 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HOMER1 homer scaffolding protein 1
HYAL2 hyaluronoglucosaminidase 2
INCENP inner centromere protein antigens 135/155kDa
ING3 inhibitor of growth family, member 3
IRF2 interferon regulatory factor 2
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KLF3 Kruppel-like factor 3 (basic)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7A lin-7 homolog A (C. elegans)
MAGEH1 melanoma antigen family H1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCM10 minichromosome maintenance complex component 10
MDM4 MDM4, p53 regulator
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL16 methyltransferase like 16
MNS1 meiosis-specific nuclear structural 1
MTA2 metastasis associated 1 family, member 2
MTMR6 myotubularin related protein 6
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
OLFML3 olfactomedin-like 3
PARD6B par-6 family cell polarity regulator beta
PCDHB3 protocadherin beta 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PPAP2C phosphatidic acid phosphatase type 2C
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
QPRT quinolinate phosphoribosyltransferase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REPS2 RALBP1 associated Eps domain containing 2
REST RE1-silencing transcription factor
SAMHD1 SAM domain and HD domain 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SECISBP2 SECIS binding protein 2
SF3A3 splicing factor 3a, subunit 3, 60kDa
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A40 solute carrier family 25, member 40
SPANXC SPANX family, member C
SPIN1 spindlin 1
SSBP3 single stranded DNA binding protein 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMEM165 transmembrane protein 165
TMOD3 tropomodulin 3 (ubiquitous)
TNRC6B trinucleotide repeat containing 6B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC13 tetratricopeptide repeat domain 13
TULP4 tubby like protein 4
ULBP2 UL16 binding protein 2
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
YIPF3 Yip1 domain family, member 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZNF248 zinc finger protein 248
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675