carbamazepine-919 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the carbamazepine-919 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM22 ADAM metallopeptidase domain 22
ADGRB2 adhesion G protein-coupled receptor B2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMH anti-Mullerian hormone
AMT aminomethyltransferase
APOE apolipoprotein E
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARPIN actin-related protein 2/3 complex inhibitor
ASCL1 achaete-scute family bHLH transcription factor 1
C2ORF68 chromosome 2 open reading frame 68
CADM4 cell adhesion molecule 4
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CARD9 caspase recruitment domain family, member 9
CCL21 chemokine (C-C motif) ligand 21
CCPG1 cell cycle progression 1
CD96 CD96 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CIZ1 CDKN1A interacting zinc finger protein 1
CLEC10A C-type lectin domain family 10, member A
CSHL1 chorionic somatomammotropin hormone-like 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXCL3 chemokine (C-X-C motif) ligand 3
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DCX doublecortin
DNAH3 dynein, axonemal, heavy chain 3
EGR1 early growth response 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPHX2 epoxide hydrolase 2, cytoplasmic
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM212B family with sequence similarity 212, member B
FLRT3 fibronectin leucine rich transmembrane protein 3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HES2 hes family bHLH transcription factor 2
HFE hemochromatosis
HMGN5 high mobility group nucleosome binding domain 5
HOXD13 homeobox D13
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL23A interleukin 23, alpha subunit p19
ITGB7 integrin, beta 7
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCTD17 potassium channel tetramerization domain containing 17
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LHX6 LIM homeobox 6
MALT1 MALT1 paracaspase
MAOA monoamine oxidase A
MAP1A microtubule-associated protein 1A
MCPH1 microcephalin 1
MED25 mediator complex subunit 25
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRAS muscle RAS oncogene homolog
MYCNOS MYCN opposite strand
NRF1 nuclear respiratory factor 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
POU6F1 POU class 6 homeobox 1
PRKD3 protein kinase D3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAD51 RAD51 recombinase
RAG2 recombination activating gene 2
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RIMS2 regulating synaptic membrane exocytosis 2
SCGB2A1 secretoglobin, family 2A, member 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETBP1 SET binding protein 1
SH3D21 SH3 domain containing 21
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOX2 SRY (sex determining region Y)-box 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SUGP1 SURP and G patch domain containing 1
SYT5 synaptotagmin V
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAGLN transgelin
TBX10 T-box 10
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TECPR2 tectonin beta-propeller repeat containing 2
TOP3A topoisomerase (DNA) III alpha
TRIO trio Rho guanine nucleotide exchange factor
TSPYL2 TSPY-like 2
TTLL5 tubulin tyrosine ligase-like family member 5
TYMS thymidylate synthetase
UBXN1 UBX domain protein 1
VIPR1 vasoactive intestinal peptide receptor 1
VLDLR very low density lipoprotein receptor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XYLT2 xylosyltransferase II

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
AKAP17A A kinase (PRKA) anchor protein 17A
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANP32A-IT1 ANP32A intronic transcript 1
ANPEP alanyl (membrane) aminopeptidase
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
B9D2 B9 protein domain 2
BAK1 BCL2-antagonist/killer 1
BFSP1 beaded filament structural protein 1, filensin
BMP4 bone morphogenetic protein 4
BPHL biphenyl hydrolase-like (serine hydrolase)
C14ORF132 chromosome 14 open reading frame 132
C2ORF44 chromosome 2 open reading frame 44
CAPG capping protein (actin filament), gelsolin-like
CASZ1 castor zinc finger 1
CBX7 chromobox homolog 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CYB5R1 cytochrome b5 reductase 1
DMC1 DNA meiotic recombinase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
FAM63A family with sequence similarity 63, member A
FBXW12 F-box and WD repeat domain containing 12
FOXA1 forkhead box A1
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
HIST1H2BF histone cluster 1, H2bf
HMHA1 histocompatibility (minor) HA-1
IER2 immediate early response 2
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KATNBL1 katanin p80 subunit B-like 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD15 potassium channel tetramerization domain containing 15
KIAA0894 KIAA0894 protein
LAMB1 laminin, beta 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAMLD1 mastermind-like domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MCOLN3 mucolipin 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL44 mitochondrial ribosomal protein L44
MRPS18C mitochondrial ribosomal protein S18C
MVD mevalonate (diphospho) decarboxylase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2L3 nuclear factor, erythroid 2-like 3
PARD6A par-6 family cell polarity regulator alpha
PC pyruvate carboxylase
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PRPH peripherin
RBL1 retinoblastoma-like 1
RBM42 RNA binding motif protein 42
RNF43 ring finger protein 43
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP7 ribosomal protein L23a pseudogene 7
SAMD9 sterile alpha motif domain containing 9
SCGB2A2 secretoglobin, family 2A, member 2
SETD1A SET domain containing 1A
SIRT2 sirtuin 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SPINK4 serine peptidase inhibitor, Kazal type 4
SYBU syntabulin (syntaxin-interacting)
TESC tescalcin
TMEM121 transmembrane protein 121
TMEM254 transmembrane protein 254
TMPRSS3 transmembrane protease, serine 3
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBQLN4 ubiquilin 4
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
YEATS4 YEATS domain containing 4
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF35 zinc finger protein 35
ZNF516 zinc finger protein 516
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76