carbachol-6742 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the carbachol-6742 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADTRP androgen-dependent TFPI-regulating protein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGEL2 angel homolog 2 (Drosophila)
ARHGAP35 Rho GTPase activating protein 35
ARTN artemin
ATP9B ATPase, class II, type 9B
AURKA aurora kinase A
BMP8B bone morphogenetic protein 8b
C14ORF79 chromosome 14 open reading frame 79
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACYBP calcyclin binding protein
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCDC40 coiled-coil domain containing 40
CCL27 chemokine (C-C motif) ligand 27
CD22 CD22 molecule
COL10A1 collagen, type X, alpha 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR4 early growth response 4
ELOVL5 ELOVL fatty acid elongase 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM63A family with sequence similarity 63, member A
FGFR1 fibroblast growth factor receptor 1
FOXG1 forkhead box G1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK2 glycerol kinase 2
GLP1R glucagon-like peptide 1 receptor
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRIA3 glutamate receptor, ionotropic, AMPA 3
HEXA hexosaminidase A (alpha polypeptide)
HIPK3 homeodomain interacting protein kinase 3
HIST1H4D histone cluster 1, H4d
IL9R interleukin 9 receptor
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA1467 KIAA1467
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LIPG lipase, endothelial
LOXL3 lysyl oxidase-like 3
LRRN3 leucine rich repeat neuronal 3
MAGEA5 melanoma antigen family A5
MMP10 matrix metallopeptidase 10
MOGAT2 monoacylglycerol O-acyltransferase 2
MVD mevalonate (diphospho) decarboxylase
NCAM1 neural cell adhesion molecule 1
NME5 NME/NM23 family member 5
NPY5R neuropeptide Y receptor Y5
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAPPA2 pappalysin 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER2 period circadian clock 2
PODXL2 podocalyxin-like 2
PON1 paraoxonase 1
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PQBP1 polyglutamine binding protein 1
PRKG1 protein kinase, cGMP-dependent, type I
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RB1 retinoblastoma 1
RHAG Rh-associated glycoprotein
RPS3A ribosomal protein S3A
SAMD4A sterile alpha motif domain containing 4A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3D21 SH3 domain containing 21
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP110 SP110 nuclear body protein
SRSF7 serine/arginine-rich splicing factor 7
SYN3 synapsin III
TBX1 T-box 1
TK2 thymidine kinase 2, mitochondrial
TNS1 tensin 1
TRIM10 tripartite motif containing 10
TSPAN9 tetraspanin 9
TTC30A tetratricopeptide repeat domain 30A
TTLL3 tubulin tyrosine ligase-like family member 3
TUBA3C tubulin, alpha 3c
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDAC3 voltage-dependent anion channel 3
VGLL3 vestigial-like family member 3
VNN2 vanin 2
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZFP30 ZFP30 zinc finger protein
ZMAT4 zinc finger, matrin-type 4
ZNF117 zinc finger protein 117
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAM2 ADAM metallopeptidase domain 2
APOC4 apolipoprotein C-IV
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHCC1 BAH domain and coiled-coil containing 1
BMP15 bone morphogenetic protein 15
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CARD8 caspase recruitment domain family, member 8
CASS4 Cas scaffolding protein family member 4
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CDIP1 cell death-inducing p53 target 1
CLDN1 claudin 1
CLEC16A C-type lectin domain family 16, member A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DCSTAMP dendrocyte expressed seven transmembrane protein
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
EPN3 epsin 3
EPPK1 epiplakin 1
FBXL7 F-box and leucine-rich repeat protein 7
FRS3 fibroblast growth factor receptor substrate 3
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMIP GEM interacting protein
GREB1L growth regulation by estrogen in breast cancer-like
GRM4 glutamate receptor, metabotropic 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IL11RA interleukin 11 receptor, alpha
ITGB7 integrin, beta 7
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00597 long intergenic non-protein coding RNA 597
LPAR4 lysophosphatidic acid receptor 4
LRRC20 leucine rich repeat containing 20
LRRC6 leucine rich repeat containing 6
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAP3K7CL MAP3K7 C-terminal like
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLYCD malonyl-CoA decarboxylase
MUC3B mucin 3B, cell surface associated
MXRA8 matrix-remodelling associated 8
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PALMD palmdelphin
PAQR4 progestin and adipoQ receptor family member IV
PARP3 poly (ADP-ribose) polymerase family, member 3
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PTK6 protein tyrosine kinase 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD6 SET domain containing 6
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNHG3 small nucleolar RNA host gene 3
SPEG SPEG complex locus
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D22B TBC1 domain family, member 22B
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOM1 target of myb1 (chicken)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF667 zinc finger protein 667
ZNF862 zinc finger protein 862