capsaicin-4612 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the capsaicin-4612 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACHE acetylcholinesterase (Yt blood group)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGMAT agmatine ureohydrolase (agmatinase)
AHSP alpha hemoglobin stabilizing protein
ANGPTL4 angiopoietin-like 4
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANO2 anoctamin 2, calcium activated chloride channel
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
BLK BLK proto-oncogene, Src family tyrosine kinase
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF12 chromosome 10 open reading frame 12
C16ORF71 chromosome 16 open reading frame 71
C21ORF2 chromosome 21 open reading frame 2
C2CD2L C2CD2-like
C4BPA complement component 4 binding protein, alpha
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CCDC177 coiled-coil domain containing 177
CCL20 chemokine (C-C motif) ligand 20
CD58 CD58 molecule
CDC14B cell division cycle 14B
CDSN corneodesmosin
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLMN calmin (calponin-like, transmembrane)
CLSTN2 calsyntenin 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CST4 cystatin S
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DMWD dystrophia myotonica, WD repeat containing
DRP2 dystrophin related protein 2
DSC1 desmocollin 1
EDN3 endothelin 3
EPHA7 EPH receptor A7
FAM163A family with sequence similarity 163, member A
FLJ11292
FZD10 frizzled class receptor 10
GPR157 G protein-coupled receptor 157
GPR20 G protein-coupled receptor 20
GPR21 G protein-coupled receptor 21
GREB1L growth regulation by estrogen in breast cancer-like
GRIA3 glutamate receptor, ionotropic, AMPA 3
HCRP1 hepatocellular carcinoma-related HCRP1
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
IFNA17 interferon, alpha 17
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
IZUMO4 IZUMO family member 4
JAG1 jagged 1
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LOC1720 dihydrofolate reductase pseudogene
MATN3 matrilin 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR8 myotubularin related protein 8
MUC4 mucin 4, cell surface associated
MYOZ2 myozenin 2
NCLN nicalin
NF1 neurofibromin 1
NOS1 nitric oxide synthase 1 (neuronal)
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDE4C phosphodiesterase 4C, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDLIM3 PDZ and LIM domain 3
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG3 pregnancy specific beta-1-glycoprotein 3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL7 ribosomal protein L7
SAPCD1 suppressor APC domain containing 1
SCAMP1 secretory carrier membrane protein 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD1 SMAD family member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPICE1 spindle and centriole associated protein 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SV2B synaptic vesicle glycoprotein 2B
TAOK2 TAO kinase 2
TCF12 transcription factor 12
TRAC T cell receptor alpha constant
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSHR thyroid stimulating hormone receptor
UBASH3A ubiquitin associated and SH3 domain containing A
VCX2 variable charge, X-linked 2
VPREB1 pre-B lymphocyte 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WSB1 WD repeat and SOCS box containing 1
ZIC3 Zic family member 3
ZNF423 zinc finger protein 423
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ADGRB2 adhesion G protein-coupled receptor B2
ANKFY1 ankyrin repeat and FYVE domain containing 1
APOLD1 apolipoprotein L domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BIRC3 baculoviral IAP repeat containing 3
BMP15 bone morphogenetic protein 15
C1GALT1C1 C1GALT1-specific chaperone 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHD8 chromodomain helicase DNA binding protein 8
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CLIC3 chloride intracellular channel 3
DCLRE1A DNA cross-link repair 1A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DTX2 deltex 2, E3 ubiquitin ligase
EGF epidermal growth factor
EMP3 epithelial membrane protein 3
EPHX2 epoxide hydrolase 2, cytoplasmic
ERAP2 endoplasmic reticulum aminopeptidase 2
ETNK2 ethanolamine kinase 2
FAT4 FAT atypical cadherin 4
FLJ21369 uncharacterized protein FLJ21369
FOXC1 forkhead box C1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GPR176 G protein-coupled receptor 176
GPR3 G protein-coupled receptor 3
GTF2I general transcription factor IIi
HDAC7 histone deacetylase 7
HELZ helicase with zinc finger
HIST1H3C histone cluster 1, H3c
HP1BP3 heterochromatin protein 1, binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL7 interleukin 7
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCTD20 potassium channel tetramerization domain containing 20
KIAA0895 KIAA0895
KIAA1456 KIAA1456
KIFAP3 kinesin-associated protein 3
KLF13 Kruppel-like factor 13
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT8P12 keratin 8 pseudogene 12
LRRK1 leucine-rich repeat kinase 1
MAP9 microtubule-associated protein 9
MED18 mediator complex subunit 18
MFGE8 milk fat globule-EGF factor 8 protein
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NAG18 NAG18 mRNA
NDP Norrie disease (pseudoglioma)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOP2 NOP2 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
NUPR1 nuclear protein, transcriptional regulator, 1
OLFML3 olfactomedin-like 3
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAIP2B poly(A) binding protein interacting protein 2B
PDE8B phosphodiesterase 8B
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
PUS1 pseudouridylate synthase 1
RGS17 regulator of G-protein signaling 17
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SPAG7 sperm associated antigen 7
ST5 suppression of tumorigenicity 5
STAC SH3 and cysteine rich domain
STK16 serine/threonine kinase 16
SYNPO synaptopodin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TGFBI transforming growth factor, beta-induced, 68kDa
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM121 transmembrane protein 121
TMEM156 transmembrane protein 156
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTLL1 tubulin tyrosine ligase-like family member 1
ZFHX3 zinc finger homeobox 3
ZNF227 zinc finger protein 227
ZNF37BP zinc finger protein 37B, pseudogene