canrenoic acid-7135 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the canrenoic acid-7135 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
AFF2 AF4/FMR2 family, member 2
AMPD3 adenosine monophosphate deaminase 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
ARTN artemin
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAIAP2 BAI1-associated protein 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C14ORF105 chromosome 14 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
C9ORF116 chromosome 9 open reading frame 116
CBX6 chromobox homolog 6
CD40 CD40 molecule, TNF receptor superfamily member 5
CENPJ centromere protein J
COL6A1 collagen, type VI, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPT1A carnitine palmitoyltransferase 1A (liver)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
DST dystonin
DTNA dystrobrevin, alpha
EMX1 empty spiracles homeobox 1
ERAP1 endoplasmic reticulum aminopeptidase 1
EXTL3 exostosin-like glycosyltransferase 3
FGFR1 fibroblast growth factor receptor 1
FKBP15 FK506 binding protein 15, 133kDa
FOSL2 FOS-like antigen 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GNRHR gonadotropin-releasing hormone receptor
GPM6B glycoprotein M6B
GPR17 G protein-coupled receptor 17
GSTCD glutathione S-transferase, C-terminal domain containing
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIDINS220 kinase D-interacting substrate, 220kDa
KIF5C kinesin family member 5C
KLF13 Kruppel-like factor 13
KLK13 kallikrein-related peptidase 13
KRT34 keratin 34, type I
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
METTL7A methyltransferase like 7A
MTCP1 mature T-cell proliferation 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP1 NEDD4 binding protein 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRX1 NLR family member X1
NNMT nicotinamide N-methyltransferase
NUP62CL nucleoporin 62kDa C-terminal like
OTUD4 OTU deubiquitinase 4
PACS1 phosphofurin acidic cluster sorting protein 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PEX26 peroxisomal biogenesis factor 26
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB2A RAB2A, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPL7 ribosomal protein L7
RUNX3 runt-related transcription factor 3
SEC24D SEC24 family member D
SGSM3 small G protein signaling modulator 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC38A7 solute carrier family 38, member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRED2 sprouty-related, EVH1 domain containing 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SRD5A3 steroid 5 alpha-reductase 3
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNPO synaptopodin
TEX261 testis expressed 261
TMC7 transmembrane channel-like 7
TMEM231 transmembrane protein 231
TMEM8B transmembrane protein 8B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TSPAN1 tetraspanin 1
TTC38 tetratricopeptide repeat domain 38
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UST uronyl-2-sulfotransferase
WDR33 WD repeat domain 33
WNT7A wingless-type MMTV integration site family, member 7A
ZNF839 zinc finger protein 839
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY7 adenylate cyclase 7
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD40 ankyrin repeat domain 40
ANXA10 annexin A10
APLP1 amyloid beta (A4) precursor-like protein 1
ARMC6 armadillo repeat containing 6
AUH AU RNA binding protein/enoyl-CoA hydratase
BAK1 BCL2-antagonist/killer 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C19ORF54 chromosome 19 open reading frame 54
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC25 coiled-coil domain containing 25
CCRL2 chemokine (C-C motif) receptor-like 2
CD70 CD70 molecule
CEP131 centrosomal protein 131kDa
CFAP44 cilia and flagella associated protein 44
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP1A charged multivesicular body protein 1A
DCAF4 DDB1 and CUL4 associated factor 4
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DET1 de-etiolated homolog 1 (Arabidopsis)
DIXDC1 DIX domain containing 1
DPY19L2P2 DPY19L2 pseudogene 2
EAF2 ELL associated factor 2
EFCAB2 EF-hand calcium binding domain 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERF Ets2 repressor factor
F8 coagulation factor VIII, procoagulant component
FAM188A family with sequence similarity 188, member A
FDXR ferredoxin reductase
FKBP2 FK506 binding protein 2, 13kDa
FPGS folylpolyglutamate synthase
GLCE glucuronic acid epimerase
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HS1BP3 HCLS1 binding protein 3
IFT22 intraflagellar transport 22
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INPPL1 inositol polyphosphate phosphatase-like 1
KIAA0894 KIAA0894 protein
KRT8P12 keratin 8 pseudogene 12
LRRC8E leucine rich repeat containing 8 family, member E
METTL8 methyltransferase like 8
MNX1 motor neuron and pancreas homeobox 1
MPST mercaptopyruvate sulfurtransferase
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYL5 myosin, light chain 5, regulatory
NCKAP1 NCK-associated protein 1
NINJ1 ninjurin 1
NUPR1 nuclear protein, transcriptional regulator, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARPBP PARP1 binding protein
PHACTR4 phosphatase and actin regulator 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PTDSS2 phosphatidylserine synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RBL1 retinoblastoma-like 1
REEP4 receptor accessory protein 4
RNFT2 ring finger protein, transmembrane 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SDAD1 SDA1 domain containing 1
SETD6 SET domain containing 6
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SREK1IP1 SREK1-interacting protein 1
STRN4 striatin, calmodulin binding protein 4
SUGCT succinyl-CoA:glutarate-CoA transferase
TDRD3 tudor domain containing 3
TMEM104 transmembrane protein 104
TMEM2 transmembrane protein 2
TNS2 tensin 2
TTC26 tetratricopeptide repeat domain 26
VASP vasodilator-stimulated phosphoprotein
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZBTB3 zinc finger and BTB domain containing 3
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF212 zinc finger protein 212
ZNF282 zinc finger protein 282
ZNF551 zinc finger protein 551
ZNF787 zinc finger protein 787