canonical wnt signaling pathway involved in metanephric kidney development Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. (Gene Ontology, GO_0061290)
External Link http://amigo.geneontology.org/amigo/term/GO:0061290
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Genes

2 genes participating in the canonical wnt signaling pathway involved in metanephric kidney development biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
GATA3 GATA binding protein 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4