canonical wnt signaling pathway involved in heart development Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. (Gene Ontology, GO_0061316)
External Link http://amigo.geneontology.org/amigo/term/GO:0061316
Similar Terms
Downloads & Tools

Genes

4 genes participating in the canonical wnt signaling pathway involved in heart development biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
LRP6 low density lipoprotein receptor-related protein 6
WNT3A wingless-type MMTV integration site family, member 3A
WNT8A wingless-type MMTV integration site family, member 8A