cancerous Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

143 genes co-occuring with the biological term cancerous in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGTR1 angiotensin II receptor, type 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA1 annexin A1
AR androgen receptor
ATOH1 atonal homolog 1 (Drosophila)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
BCAS3 breast carcinoma amplified sequence 3
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1QA complement component 1, q subcomponent, A chain
CDCA8 cell division cycle associated 8
CDCP1 CUB domain containing protein 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CLEC10A C-type lectin domain family 10, member A
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSL cathepsin L
CUZD1 CUB and zona pellucida-like domains 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR6 chemokine (C-X-C motif) receptor 6
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DLC1 DLC1 Rho GTPase activating protein
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPYD dihydropyrimidine dehydrogenase
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ERBB2 erb-b2 receptor tyrosine kinase 2
FHIT fragile histidine triad
FOXA1 forkhead box A1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
GJB1 gap junction protein, beta 1, 32kDa
GKN1 gastrokine 1
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSK3B glycogen synthase kinase 3 beta
GSTM4 glutathione S-transferase mu 4
HAMP hepcidin antimicrobial peptide
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H2BE histone cluster 2, H2be
HK1 hexokinase 1
HMGB1 high mobility group box 1
HOXA13 homeobox A13
HSPA1B heat shock 70kDa protein 1B
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL6 interleukin 6
ILK integrin-linked kinase
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KDM1A lysine (K)-specific demethylase 1A
KIAA1524 KIAA1524
KLF9 Kruppel-like factor 9
KLK6 kallikrein-related peptidase 6
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LEFTY1 left-right determination factor 1
LGALS9 lectin, galactoside-binding, soluble, 9
LHCGR luteinizing hormone/choriogonadotropin receptor
LIMS1 LIM and senescent cell antigen-like domains 1
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MECP2 methyl CpG binding protein 2
MIR21 microRNA 21
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MMP2 matrix metallopeptidase 2
MTA1 metastasis associated 1
MTSS1 metastasis suppressor 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NCL nucleolin
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCA3 prostate cancer associated 3 (non-protein coding)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDYN prodynorphin
PELP1 proline, glutamate and leucine rich protein 1
PLAUR plasminogen activator, urokinase receptor
POU5F1 POU class 5 homeobox 1
PRKCZ protein kinase C, zeta
PSCA prostate stem cell antigen
PTEN phosphatase and tensin homolog
PTTG1 pituitary tumor-transforming 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBM5 RNA binding motif protein 5
RHOA ras homolog family member A
SATB1 SATB homeobox 1
SCGB3A1 secretoglobin, family 3A, member 1
SECTM1 secreted and transmembrane 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGPL1 sphingosine-1-phosphate lyase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SMAD2 SMAD family member 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STS steroid sulfatase (microsomal), isozyme S
STYK1 serine/threonine/tyrosine kinase 1
SULF1 sulfatase 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TK1 thymidine kinase 1, soluble
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMEM97 transmembrane protein 97
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TP53 tumor protein p53
TP73 tumor protein p73
TSPAN1 tetraspanin 1
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
UCN3 urocortin 3
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
WNT1 wingless-type MMTV integration site family, member 1
WWOX WW domain containing oxidoreductase
XAGE1E X antigen family, member 1E
YTHDC1 YTH domain containing 1
ZEB1 zinc finger E-box binding homeobox 1