canavanine-4197 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the canavanine-4197 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
ARMC4 armadillo repeat containing 4
ATG10 autophagy related 10
AUTS2 autism susceptibility candidate 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C11ORF63 chromosome 11 open reading frame 63
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA1 carbonic anhydrase I
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAPN3 calpain 3, (p94)
CD22 CD22 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CLIC5 chloride intracellular channel 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGCR8 DGCR8 microprocessor complex subunit
DHRS9 dehydrogenase/reductase (SDR family) member 9
DICER1 dicer 1, ribonuclease type III
DMBT1 deleted in malignant brain tumors 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK4 docking protein 4
EMID1 EMI domain containing 1
ETV6 ets variant 6
FGL1 fibrinogen-like 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GALC galactosylceramidase
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPR27 G protein-coupled receptor 27
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXD11 homeobox D11
HSF2BP heat shock transcription factor 2 binding protein
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IFITM1 interferon induced transmembrane protein 1
IFNA16 interferon, alpha 16
IGLV4-60 immunoglobulin lambda variable 4-60
IL22 interleukin 22
IRF4 interferon regulatory factor 4
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMA4 laminin, alpha 4
LARGE like-glycosyltransferase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00312 long intergenic non-protein coding RNA 312
LOC257152 uncharacterized LOC257152
MAN2C1 mannosidase, alpha, class 2C, member 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTRF1L mitochondrial translational release factor 1-like
MYF5 myogenic factor 5
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NPC1 Niemann-Pick disease, type C1
NPTXR neuronal pentraxin receptor
NRN1 neuritin 1
OSBPL10 oxysterol binding protein-like 10
OVOL2 ovo-like zinc finger 2
PAH phenylalanine hydroxylase
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH1 protocadherin 1
PDE10A phosphodiesterase 10A
PLCL2 phospholipase C-like 2
POFUT2 protein O-fucosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PVR poliovirus receptor
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RUNX1 runt-related transcription factor 1
SCARB1 scavenger receptor class B, member 1
SELPLG selectin P ligand
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC38A3 solute carrier family 38, member 3
SLC39A9 solute carrier family 39, member 9
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAOK1 TAO kinase 1
TCF20 transcription factor 20 (AR1)
TDRKH tudor and KH domain containing
TP73-AS1 TP73 antisense RNA 1
TRA2A transformer 2 alpha homolog (Drosophila)
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSGA10 testis specific, 10
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WFDC2 WAP four-disulfide core domain 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF280B zinc finger protein 280B
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACE angiotensin I converting enzyme
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOL6 apolipoprotein L, 6
ARRB2 arrestin, beta 2
AXIN1 axin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
C22ORF46 chromosome 22 open reading frame 46
C6ORF47 chromosome 6 open reading frame 47
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CD68 CD68 molecule
CD70 CD70 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEMP1 cementum protein 1
CISH cytokine inducible SH2-containing protein
CLDN1 claudin 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CXCL3 chemokine (C-X-C motif) ligand 3
DDN dendrin
DLK2 delta-like 2 homolog (Drosophila)
DNM3 dynamin 3
EBF2 early B-cell factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EN2 engrailed homeobox 2
FKBP5 FK506 binding protein 5
FRMPD1 FERM and PDZ domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPR1 G protein-coupled receptor 1
GPR3 G protein-coupled receptor 3
HIST1H2BN histone cluster 1, H2bn
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HOOK1 hook microtubule-tethering protein 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
KRT8P12 keratin 8 pseudogene 12
LPAR4 lysophosphatidic acid receptor 4
LY6D lymphocyte antigen 6 complex, locus D
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MANBA mannosidase, beta A, lysosomal
MAP6D1 MAP6 domain containing 1
MCTP1 multiple C2 domains, transmembrane 1
MTCP1 mature T-cell proliferation 1
NABP2 nucleic acid binding protein 2
NME3 NME/NM23 nucleoside diphosphate kinase 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PAX9 paired box 9
PCDH12 protocadherin 12
PELP1 proline, glutamate and leucine rich protein 1
PEX26 peroxisomal biogenesis factor 26
PID1 phosphotyrosine interaction domain containing 1
PLBD1 phospholipase B domain containing 1
PLD3 phospholipase D family, member 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRR7 proline rich 7 (synaptic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S1PR1 sphingosine-1-phosphate receptor 1
SLC35F6 solute carrier family 35, member F6
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOX12 SRY (sex determining region Y)-box 12
SUGCT succinyl-CoA:glutarate-CoA transferase
TEP1 telomerase-associated protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMP4 TIMP metallopeptidase inhibitor 4
TLN1 talin 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNS2 tensin 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN2 tetraspanin 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UNC119 unc-119 homolog (C. elegans)
VEGFB vascular endothelial growth factor B
VGLL3 vestigial-like family member 3
XAB2 XPA binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF10 zinc finger protein 10
ZNF232 zinc finger protein 232
ZNF250 zinc finger protein 250