canadine-4020 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the canadine-4020 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL3 adhesion G protein-coupled receptor L3
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ANP32A-IT1 ANP32A intronic transcript 1
APOA1 apolipoprotein A-I
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
BPY2 basic charge, Y-linked, 2
C5AR2 complement component 5a receptor 2
CALHM2 calcium homeostasis modulator 2
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CD79A CD79a molecule, immunoglobulin-associated alpha
CELP carboxyl ester lipase pseudogene
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC10A C-type lectin domain family 10, member A
CLIC2 chloride intracellular channel 2
COL10A1 collagen, type X, alpha 1
COL2A1 collagen, type II, alpha 1
CSN3 casein kappa
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DDO D-aspartate oxidase
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLX5 distal-less homeobox 5
DRP2 dystrophin related protein 2
EBF2 early B-cell factor 2
EPB41 erythrocyte membrane protein band 4.1
FAM163A family with sequence similarity 163, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXL1 forkhead box L1
GALR2 galanin receptor 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GLP1R glucagon-like peptide 1 receptor
GMPR guanosine monophosphate reductase
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GPR37L1 G protein-coupled receptor 37 like 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HESX1 HESX homeobox 1
HOXA7 homeobox A7
HOXD13 homeobox D13
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGH immunoglobulin heavy locus
IMPG1 interphotoreceptor matrix proteoglycan 1
INS insulin
INVS inversin
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0125 KIAA0125
KIF1C kinesin family member 1C
KIF25-AS1 KIF25 antisense RNA 1
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LOXL3 lysyl oxidase-like 3
LRRN3 leucine rich repeat neuronal 3
MAP2K5 mitogen-activated protein kinase kinase 5
MIER2 mesoderm induction early response 1, family member 2
MMRN2 multimerin 2
NGLY1 N-glycanase 1
NLRP3 NLR family, pyrin domain containing 3
NRG1 neuregulin 1
NT5M 5',3'-nucleotidase, mitochondrial
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OAZ3 ornithine decarboxylase antizyme 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
ORM1 orosomucoid 1
PBOV1 prostate and breast cancer overexpressed 1
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLCH1 phospholipase C, eta 1
POU6F2 POU class 6 homeobox 2
PRSS50 protease, serine, 50
PSG9 pregnancy specific beta-1-glycoprotein 9
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTCH2 patched 2
RB1 retinoblastoma 1
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RDH8 retinol dehydrogenase 8 (all-trans)
SCAND2P SCAN domain containing 2 pseudogene
SCGB2A1 secretoglobin, family 2A, member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS3 suppressor of cytokine signaling 3
SOX15 SRY (sex determining region Y)-box 15
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYCE1L synaptonemal complex central element protein 1-like
TCF15 transcription factor 15 (basic helix-loop-helix)
TJP3 tight junction protein 3
TOX thymocyte selection-associated high mobility group box
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC22 tetratricopeptide repeat domain 22
TTC38 tetratricopeptide repeat domain 38
WNT3 wingless-type MMTV integration site family, member 3
ZCCHC11 zinc finger, CCHC domain containing 11

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCY6 adenylate cyclase 6
AGMAT agmatine ureohydrolase (agmatinase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMDHD2 amidohydrolase domain containing 2
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG4 BCL2-associated athanogene 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF30 chromosome 11 open reading frame 30
C5 complement component 5
CA9 carbonic anhydrase IX
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASZ1 castor zinc finger 1
CBX4 chromobox homolog 4
CCS copper chaperone for superoxide dismutase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
CLDN11 claudin 11
CNTLN centlein, centrosomal protein
CTSO cathepsin O
EDN1 endothelin 1
ELP6 elongator acetyltransferase complex subunit 6
EMP3 epithelial membrane protein 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERO1LB ERO1-like beta (S. cerevisiae)
ETNK2 ethanolamine kinase 2
EVPL envoplakin
FAT4 FAT atypical cadherin 4
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FSTL3 follistatin-like 3 (secreted glycoprotein)
GDAP1 ganglioside induced differentiation associated protein 1
GPC3 glypican 3
GPR3 G protein-coupled receptor 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HSF2BP heat shock transcription factor 2 binding protein
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL17RB interleukin 17 receptor B
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
LIG4 ligase IV, DNA, ATP-dependent
LYPD3 LY6/PLAUR domain containing 3
MANBA mannosidase, beta A, lysosomal
MAST3 microtubule associated serine/threonine kinase 3
MMP3 matrix metallopeptidase 3
MON1B MON1 secretory trafficking family member B
MRPS34 mitochondrial ribosomal protein S34
MXD3 MAX dimerization protein 3
NDRG4 NDRG family member 4
NME5 NME/NM23 family member 5
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE8B phosphodiesterase 8B
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PRR4 proline rich 4 (lacrimal)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK7 protein tyrosine kinase 7 (inactive)
R3HCC1L R3H domain and coiled-coil containing 1-like
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPH3AL rabphilin 3A-like (without C2 domains)
S100A6 S100 calcium binding protein A6
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIRT6 sirtuin 6
SLAMF7 SLAM family member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMG9 SMG9 nonsense mediated mRNA decay factor
SMR3A submaxillary gland androgen regulated protein 3A
SPRYD7 SPRY domain containing 7
SSTR4 somatostatin receptor 4
STK16 serine/threonine kinase 16
TH tyrosine hydroxylase
TMEM242 transmembrane protein 242
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAPPC6A trafficking protein particle complex 6A
TXK TXK tyrosine kinase
TXLNG taxilin gamma
USP18 ubiquitin specific peptidase 18
WDR33 WD repeat domain 33
WFDC2 WAP four-disulfide core domain 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF230 zinc finger protein 230
ZNF492 zinc finger protein 492
ZNF606 zinc finger protein 606
ZNF711 zinc finger protein 711