canadine-2163 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the canadine-2163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR2A activin A receptor, type IIA
AJAP1 adherens junctions associated protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOH apolipoprotein H (beta-2-glycoprotein I)
ATG10 autophagy related 10
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF95 chromosome 1 open reading frame 95
CALML3 calmodulin-like 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN9 calpain 9
CASZ1 castor zinc finger 1
CCDC57 coiled-coil domain containing 57
CD200 CD200 molecule
CD84 CD84 molecule
CDH8 cadherin 8, type 2
CFB complement factor B
COL6A1 collagen, type VI, alpha 1
CRMP1 collapsin response mediator protein 1
DDO D-aspartate oxidase
DDR1 discoidin domain receptor tyrosine kinase 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DMWD dystrophia myotonica, WD repeat containing
DSPP dentin sialophosphoprotein
FBXO2 F-box protein 2
GK2 glycerol kinase 2
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRPR gastrin-releasing peptide receptor
GSN gelsolin
HLA-DMB major histocompatibility complex, class II, DM beta
IFI6 interferon, alpha-inducible protein 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL12RB1 interleukin 12 receptor, beta 1
IL17RC interleukin 17 receptor C
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA1109 KIAA1109
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LY9 lymphocyte antigen 9
MAP4 microtubule-associated protein 4
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MLF1 myeloid leukemia factor 1
MMP19 matrix metallopeptidase 19
MXD3 MAX dimerization protein 3
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PAWR PRKC, apoptosis, WT1, regulator
PAX7 paired box 7
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PICALM phosphatidylinositol binding clathrin assembly protein
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G3 phospholipase A2, group III
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPARD peroxisome proliferator-activated receptor delta
PRODH2 proline dehydrogenase (oxidase) 2
PURG purine-rich element binding protein G
PVR poliovirus receptor
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS14 regulator of G-protein signaling 14
RHO rhodopsin
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RTEL1 regulator of telomere elongation helicase 1
S100A11 S100 calcium binding protein A11
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC35G2 solute carrier family 35, member G2
SMAD6 SMAD family member 6
SSX3 synovial sarcoma, X breakpoint 3
STAB2 stabilin 2
SV2B synaptic vesicle glycoprotein 2B
SYN3 synapsin III
SYNM synemin, intermediate filament protein
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TSKU tsukushi, small leucine rich proteoglycan
TSPAN2 tetraspanin 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VSNL1 visinin-like 1
WTAP Wilms tumor 1 associated protein
XDH xanthine dehydrogenase
ZBTB7A zinc finger and BTB domain containing 7A
ZNF205 zinc finger protein 205
ZNF335 zinc finger protein 335
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM23 ADAM metallopeptidase domain 23
AKTIP AKT interacting protein
APOL6 apolipoprotein L, 6
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASGR2 asialoglycoprotein receptor 2
ATAT1 alpha tubulin acetyltransferase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD18 BTB (POZ) domain containing 18
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
CCDC186 coiled-coil domain containing 186
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CHMP7 charged multivesicular body protein 7
CIDEC cell death-inducing DFFA-like effector c
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTN1 contactin 1
CTAGE9 CTAGE family, member 9
CXORF56 chromosome X open reading frame 56
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
DVL1 dishevelled segment polarity protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM127B family with sequence similarity 127, member B
FAM160B2 family with sequence similarity 160, member B2
FAM168B family with sequence similarity 168, member B
FBP1 fructose-1,6-bisphosphatase 1
FJX1 four jointed box 1 (Drosophila)
FKBP5 FK506 binding protein 5
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXC1 forkhead box C1
FRMD1 FERM domain containing 1
GDAP1 ganglioside induced differentiation associated protein 1
GLI3 GLI family zinc finger 3
GPX2 glutathione peroxidase 2
GRIP2 glutamate receptor interacting protein 2
GSDMD gasdermin D
GSTA3 glutathione S-transferase alpha 3
GSTT1 glutathione S-transferase theta 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1T histone cluster 1, H1t
HLA-DMA major histocompatibility complex, class II, DM alpha
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INCENP inner centromere protein antigens 135/155kDa
LIME1 Lck interacting transmembrane adaptor 1
LOC157562 uncharacterized LOC157562
LPAR6 lysophosphatidic acid receptor 6
LRP5 low density lipoprotein receptor-related protein 5
LTBP3 latent transforming growth factor beta binding protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEH1 melanoma antigen family H1
MAP3K7CL MAP3K7 C-terminal like
MPZ myelin protein zero
MX1 MX dynamin-like GTPase 1
MYOZ3 myozenin 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
PMP22 peripheral myelin protein 22
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPT2 palmitoyl-protein thioesterase 2
PTGES2 prostaglandin E synthase 2
RCL1 RNA terminal phosphate cyclase-like 1
RHOB ras homolog family member B
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
SCGB2A2 secretoglobin, family 2A, member 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLN sarcolipin
SNAI1 snail family zinc finger 1
SOCS7 suppressor of cytokine signaling 7
STX1A syntaxin 1A (brain)
TEC tec protein tyrosine kinase
TFF2 trefoil factor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
ZNF137P zinc finger protein 137, pseudogene
ZNF324 zinc finger protein 324
ZNF749 zinc finger protein 749