calmidazolium-486 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the calmidazolium-486 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFAP70 cilia and flagella associated protein 70
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCF1 cardiotrophin-like cytokine factor 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP22 dual specificity phosphatase 22
EFNA1 ephrin-A1
EGR1 early growth response 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GPR3 G protein-coupled receptor 3
GRIK5 glutamate receptor, ionotropic, kainate 5
H2BFS H2B histone family, member S (pseudogene)
HES1 hes family bHLH transcription factor 1
HIST1H1D histone cluster 1, H1d
HIST1H2AE histone cluster 1, H2ae
HIST1H2AI histone cluster 1, H2ai
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HIST1H4J histone cluster 1, H4j
HIST2H2BE histone cluster 2, H2be
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IL6 interleukin 6
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MCL1 myeloid cell leukemia 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MVK mevalonate kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NADK NAD kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
PADI1 peptidyl arginine deiminase, type I
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRB1 proline-rich protein BstNI subfamily 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS16 regulator of G-protein signaling 16
RING1 ring finger protein 1
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3BP2 SH3-domain binding protein 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOCS2 suppressor of cytokine signaling 2
SQSTM1 sequestosome 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK2 tyrosine kinase, non-receptor, 2
TRIB1 tribbles pseudokinase 1
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMPH amphiphysin
B3GNT1
BCL9 B-cell CLL/lymphoma 9
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD2 BTB (POZ) domain containing 2
C12ORF29 chromosome 12 open reading frame 29
C16ORF59 chromosome 16 open reading frame 59
C2CD5 C2 calcium-dependent domain containing 5
C2ORF49 chromosome 2 open reading frame 49
CA2 carbonic anhydrase II
CCDC51 coiled-coil domain containing 51
CCL16 chemokine (C-C motif) ligand 16
CD151 CD151 molecule (Raph blood group)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COPZ2 coatomer protein complex, subunit zeta 2
CPTP ceramide-1-phosphate transfer protein
CRTAC1 cartilage acidic protein 1
CTNNBIP1 catenin, beta interacting protein 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCLRE1A DNA cross-link repair 1A
DPEP1 dipeptidase 1 (renal)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP9 dual specificity phosphatase 9
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
EDA2R ectodysplasin A2 receptor
EHD3 EH-domain containing 3
ELP3 elongator acetyltransferase complex subunit 3
EPHA4 EPH receptor A4
EVPL envoplakin
FAM86C1 family with sequence similarity 86, member C1
FANCF Fanconi anemia, complementation group F
FKBP10 FK506 binding protein 10, 65 kDa
FOXD1 forkhead box D1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBAP1 glucosidase, beta, acid pseudogene 1
GEMIN6 gem (nuclear organelle) associated protein 6
GLMN glomulin, FKBP associated protein
GMPPB GDP-mannose pyrophosphorylase B
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPR15 G protein-coupled receptor 15
GUCA1B guanylate cyclase activator 1B (retina)
HMGB3P1 high mobility group box 3 pseudogene 1
ICAM3 intercellular adhesion molecule 3
IFITM3 interferon induced transmembrane protein 3
IL15RA interleukin 15 receptor, alpha
JAM3 junctional adhesion molecule 3
JOSD1 Josephin domain containing 1
KLF15 Kruppel-like factor 15
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
KREMEN2 kringle containing transmembrane protein 2
KRT8P12 keratin 8 pseudogene 12
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LMO3 LIM domain only 3 (rhombotin-like 2)
MCHR1 melanin-concentrating hormone receptor 1
MGST2 microsomal glutathione S-transferase 2
MGST3 microsomal glutathione S-transferase 3
MTERF4 mitochondrial transcription termination factor 4
MYL5 myosin, light chain 5, regulatory
NCS1 neuronal calcium sensor 1
NELFE negative elongation factor complex member E
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUBP2 nucleotide binding protein 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARD6A par-6 family cell polarity regulator alpha
PES1 pescadillo ribosomal biogenesis factor 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKD2L1 polycystic kidney disease 2-like 1
PLAC1 placenta-specific 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRDM14 PR domain containing 14
PROL1 proline rich, lacrimal 1
RNF141 ring finger protein 141
RWDD2A RWD domain containing 2A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC10A3 solute carrier family 10, member 3
SPON2 spondin 2, extracellular matrix protein
SUSD4 sushi domain containing 4
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAOK1 TAO kinase 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TCTN1 tectonic family member 1
TESK1 testis-specific kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM51 transmembrane protein 51
TOE1 target of EGR1, member 1 (nuclear)
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VEGFB vascular endothelial growth factor B
WRB tryptophan rich basic protein
ZFP30 ZFP30 zinc finger protein
ZNRF4 zinc and ring finger 4