calcium folinate-2579 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the calcium folinate-2579 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AIM1L absent in melanoma 1-like
AMH anti-Mullerian hormone
AMIGO2 adhesion molecule with Ig-like domain 2
AQP1 aquaporin 1 (Colton blood group)
ARG1 arginase 1
BDNF brain-derived neurotrophic factor
BTG2 BTG family, member 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDC14A cell division cycle 14A
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CECR1 cat eye syndrome chromosome region, candidate 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP250 centrosomal protein 250kDa
CLCN5 chloride channel, voltage-sensitive 5
COL14A1 collagen, type XIV, alpha 1
CPQ carboxypeptidase Q
CRYGD crystallin, gamma D
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CUL7 cullin 7
DAPK3 death-associated protein kinase 3
DDAH2 dimethylarginine dimethylaminohydrolase 2
DGKE diacylglycerol kinase, epsilon 64kDa
DNASE2 deoxyribonuclease II, lysosomal
DPY19L1 dpy-19-like 1 (C. elegans)
DUSP4 dual specificity phosphatase 4
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXG1 forkhead box G1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJA4 gap junction protein, alpha 4, 37kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR132 G protein-coupled receptor 132
GPR153 G protein-coupled receptor 153
GSN gelsolin
HAB1 B1 for mucin
HOMER3 homer scaffolding protein 3
HOXA1 homeobox A1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDR kinase insert domain receptor
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LARP7 La ribonucleoprotein domain family, member 7
MEFV Mediterranean fever
MRC2 mannose receptor, C type 2
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC8 mucin 8
MVP major vault protein
MX1 MX dynamin-like GTPase 1
MYOF myoferlin
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PCGF2 polycomb group ring finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKP4 plakophilin 4
PLSCR3 phospholipid scramblase 3
POU3F2 POU class 3 homeobox 2
PTK2B protein tyrosine kinase 2 beta
PTPRB protein tyrosine phosphatase, receptor type, B
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RARB retinoic acid receptor, beta
RGS13 regulator of G-protein signaling 13
RHOH ras homolog family member H
RPL13 ribosomal protein L13
RPL13P5 ribosomal protein L13 pseudogene 5
RRBP1 ribosome binding protein 1
RRP1B ribosomal RNA processing 1B
RS1 retinoschisin 1
RTCA RNA 3'-terminal phosphate cyclase
RTEL1 regulator of telomere elongation helicase 1
RXRB retinoid X receptor, beta
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHB Src homology 2 domain containing adaptor protein B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLITRK5 SLIT and NTRK-like family, member 5
SMAD3 SMAD family member 3
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNN stannin
SPRR2B small proline-rich protein 2B
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TBC1D30 TBC1 domain family, member 30
TIMP2 TIMP metallopeptidase inhibitor 2
TLK1 tousled-like kinase 1
TMCO3 transmembrane and coiled-coil domains 3
TMEM140 transmembrane protein 140
TMEM180 transmembrane protein 180
TRIO trio Rho guanine nucleotide exchange factor

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACP6 acid phosphatase 6, lysophosphatidic
ADGB androglobin
AIRE autoimmune regulator
AMT aminomethyltransferase
APOL6 apolipoprotein L, 6
ASIC1 acid sensing (proton gated) ion channel 1
ATAT1 alpha tubulin acetyltransferase 1
BHLHE41 basic helix-loop-helix family, member e41
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTNL3 butyrophilin-like 3
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CD79A CD79a molecule, immunoglobulin-associated alpha
CD9 CD9 molecule
CDK20 cyclin-dependent kinase 20
CFAP45 cilia and flagella associated protein 45
CFP complement factor properdin
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DKFZP434L187 uncharacterized LOC26082
DOK3 docking protein 3
DUSP2 dual specificity phosphatase 2
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO31 F-box protein 31
FBXO40 F-box protein 40
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FURIN furin (paired basic amino acid cleaving enzyme)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GSN-AS1 GSN antisense RNA 1
GSTT1 glutathione S-transferase theta 1
HIST1H2BN histone cluster 1, H2bn
HIST1H3B histone cluster 1, H3b
HIST1H3G histone cluster 1, H3g
HOXB9 homeobox B9
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGKV3-20 immunoglobulin kappa variable 3-20
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1024 KIAA1024
LINC00260 long intergenic non-protein coding RNA 260
LINC00597 long intergenic non-protein coding RNA 597
LNPEP leucyl/cystinyl aminopeptidase
LRRC49 leucine rich repeat containing 49
MARC1 mitochondrial amidoxime reducing component 1
MGP matrix Gla protein
MUC3A mucin 3A, cell surface associated
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NOD2 nucleotide-binding oligomerization domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NRAP nebulin-related anchoring protein
OCLN occludin
PAIP2B poly(A) binding protein interacting protein 2B
PBOV1 prostate and breast cancer overexpressed 1
PDLIM1 PDZ and LIM domain 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLA2G1B phospholipase A2, group IB (pancreas)
PLAT plasminogen activator, tissue
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMEL premelanosome protein
PMFBP1 polyamine modulated factor 1 binding protein 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
SCN10A sodium channel, voltage gated, type X alpha subunit
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMR3A submaxillary gland androgen regulated protein 3A
SNRPN small nuclear ribonucleoprotein polypeptide N
SPEF1 sperm flagellar 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAS2R1 taste receptor, type 2, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TICAM1 toll-like receptor adaptor molecule 1
TMC5 transmembrane channel-like 5
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TPM3 tropomyosin 3
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN13 tetraspanin 13
UPB1 ureidopropionase, beta
USB1 U6 snRNA biogenesis 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF280A zinc finger protein 280A
ZNF552 zinc finger protein 552