caffeic acid-5352 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the caffeic acid-5352 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
ALPK1 alpha-kinase 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC1 apolipoprotein C-I
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP9A ATPase, class II, type 9A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C19ORF73 chromosome 19 open reading frame 73
C5AR2 complement component 5a receptor 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DAXX death-domain associated protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA5 ephrin-A5
ERN2 endoplasmic reticulum to nucleus signaling 2
EVI5 ecotropic viral integration site 5
EWSR1 EWS RNA-binding protein 1
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FLOT1 flotillin 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GK2 glycerol kinase 2
GSTA4 glutathione S-transferase alpha 4
HCFC1 host cell factor C1
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2AJ histone cluster 1, H2aj
HLA-E major histocompatibility complex, class I, E
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPS1 Hermansky-Pudlak syndrome 1
INPP5J inositol polyphosphate-5-phosphatase J
INSR insulin receptor
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0355 KIAA0355
KLHL22 kelch-like family member 22
LAMB3 laminin, beta 3
LIG3 ligase III, DNA, ATP-dependent
LYRM9 LYR motif containing 9
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MEFV Mediterranean fever
MPPE1 metallophosphoesterase 1
MYOF myoferlin
N4BP1 NEDD4 binding protein 1
NCR2 natural cytotoxicity triggering receptor 2
NIPAL2 NIPA-like domain containing 2
NMT2 N-myristoyltransferase 2
NOD1 nucleotide-binding oligomerization domain containing 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRF1 perforin 1 (pore forming protein)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RGS10 regulator of G-protein signaling 10
RPL35A ribosomal protein L35a
SF3B3 splicing factor 3b, subunit 3, 130kDa
SH2B1 SH2B adaptor protein 1
SH3BP2 SH3-domain binding protein 2
SIX1 SIX homeobox 1
SLC16A4 solute carrier family 16, member 4
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMA4 glucuronidase, beta pseudogene
SOCS1 suppressor of cytokine signaling 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSX3 synovial sarcoma, X breakpoint 3
STK11 serine/threonine kinase 11
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC23 tetratricopeptide repeat domain 23
TWF2 twinfilin actin binding protein 2
UBE3B ubiquitin protein ligase E3B
UBTD1 ubiquitin domain containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZMYM6 zinc finger, MYM-type 6
ZNF286A zinc finger protein 286A
ZNF442 zinc finger protein 442
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
AEN apoptosis enhancing nuclease
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATG4A autophagy related 4A, cysteine peptidase
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BABAM1 BRISC and BRCA1 A complex member 1
BACE1 beta-site APP-cleaving enzyme 1
BBS7 Bardet-Biedl syndrome 7
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C14ORF132 chromosome 14 open reading frame 132
C1ORF159 chromosome 1 open reading frame 159
CCNE1 cyclin E1
CDK9 cyclin-dependent kinase 9
CLDN4 claudin 4
CRABP1 cellular retinoic acid binding protein 1
CRYBG3 beta-gamma crystallin domain containing 3
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNBIP1 catenin, beta interacting protein 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4B DENN/MADD domain containing 4B
DHCR24 24-dehydrocholesterol reductase
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FAM179B family with sequence similarity 179, member B
FAM193A family with sequence similarity 193, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
FOXJ2 forkhead box J2
FPGT fucose-1-phosphate guanylyltransferase
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GFRA1 GDNF family receptor alpha 1
GMIP GEM interacting protein
GTPBP2 GTP binding protein 2
HIST1H1D histone cluster 1, H1d
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
INSIG2 insulin induced gene 2
ISG15 ISG15 ubiquitin-like modifier
KLHL26 kelch-like family member 26
LINS lines homolog (Drosophila)
LMNB2 lamin B2
LYPD1 LY6/PLAUR domain containing 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NARFL nuclear prelamin A recognition factor-like
NCAPD3 non-SMC condensin II complex, subunit D3
NDE1 nudE neurodevelopment protein 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAQR6 progestin and adipoQ receptor family member VI
PCOLCE2 procollagen C-endopeptidase enhancer 2
PHACTR4 phosphatase and actin regulator 4
PHGDH phosphoglycerate dehydrogenase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMM1 phosphomannomutase 1
PPL periplakin
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM42 RNA binding motif protein 42
REPS2 RALBP1 associated Eps domain containing 2
RHOC ras homolog family member C
RNF121 ring finger protein 121
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFT2D2 SFT2 domain containing 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC41A3 solute carrier family 41, member 3
SNX16 sorting nexin 16
SPANXC SPANX family, member C
STK16 serine/threonine kinase 16
SUSD6 sushi domain containing 6
TGFB3 transforming growth factor, beta 3
THAP1 THAP domain containing, apoptosis associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THOP1 thimet oligopeptidase 1
TLN1 talin 1
TMEM260 transmembrane protein 260
TMEM38B transmembrane protein 38B
TNRC6B trinucleotide repeat containing 6B
TPST1 tyrosylprotein sulfotransferase 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF189 zinc finger protein 189
ZNF273 zinc finger protein 273
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF408 zinc finger protein 408
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF654 zinc finger protein 654
ZNF7 zinc finger protein 7
ZNF787 zinc finger protein 787