butyl hydroxybenzoate-5608 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the butyl hydroxybenzoate-5608 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
ADAM7 ADAM metallopeptidase domain 7
ADGRB1 adhesion G protein-coupled receptor B1
AKR1C2 aldo-keto reductase family 1, member C2
ALDOB aldolase B, fructose-bisphosphate
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATF3 activating transcription factor 3
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATXN2L ataxin 2-like
ATXN8OS ATXN8 opposite strand (non-protein coding)
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF9 chromosome 9 open reading frame 9
CCKAR cholecystokinin A receptor
CD82 CD82 molecule
CEP41 centrosomal protein 41kDa
CLEC2B C-type lectin domain family 2, member B
CLTA clathrin, light chain A
COL13A1 collagen, type XIII, alpha 1
COL1A1 collagen, type I, alpha 1
CPM carboxypeptidase M
DCTN1 dynactin 1
DGKQ diacylglycerol kinase, theta 110kDa
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOK2 docking protein 2, 56kDa
DUOX2 dual oxidase 2
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EGR3 early growth response 3
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGFR2 fibroblast growth factor receptor 2
FRMD4B FERM domain containing 4B
FRMD8 FERM domain containing 8
FSTL3 follistatin-like 3 (secreted glycoprotein)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GZMK granzyme K (granzyme 3; tryptase II)
HDAC11 histone deacetylase 11
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HPCAL4 hippocalcin like 4
HYAL3 hyaluronoglucosaminidase 3
IDUA iduronidase, alpha-L-
IFFO1 intermediate filament family orphan 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
IPCEF1 interaction protein for cytohesin exchange factors 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KERA keratocan
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0391 KIAA0391
KRT9 keratin 9, type I
LAMC2 laminin, gamma 2
LINC00652 long intergenic non-protein coding RNA 652
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBD2 methyl-CpG binding domain protein 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFSD7 major facilitator superfamily domain containing 7
MLXIP MLX interacting protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOTCH3 notch 3
NOVA2 neuro-oncological ventral antigen 2
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PIGR polymeric immunoglobulin receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
PRDX2 peroxiredoxin 2
PTGDR2 prostaglandin D2 receptor 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS12 regulator of G-protein signaling 12
RIMS3 regulating synaptic membrane exocytosis 3
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2D1A SH2 domain containing 1A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHOX2 short stature homeobox 2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SOX2 SRY (sex determining region Y)-box 2
SPRR2B small proline-rich protein 2B
T T, brachyury homolog (mouse)
TCP11L1 t-complex 11, testis-specific-like 1
THPO thrombopoietin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM10 tripartite motif containing 10
TYMP thymidine phosphorylase
VIPR1 vasoactive intestinal peptide receptor 1
VWA5A von Willebrand factor A domain containing 5A
ZFP64 ZFP64 zinc finger protein
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADTRP androgen-dependent TFPI-regulating protein
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD36 ankyrin repeat domain 36
ANP32A-IT1 ANP32A intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BAHCC1 BAH domain and coiled-coil containing 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CAPRIN2 caprin family member 2
CCDC132 coiled-coil domain containing 132
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLEC4E C-type lectin domain family 4, member E
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPNE7 copine VII
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DRD1 dopamine receptor D1
EXO5 exonuclease 5
F9 coagulation factor IX
FAM188A family with sequence similarity 188, member A
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GEMIN8 gem (nuclear organelle) associated protein 8
GJA8 gap junction protein, alpha 8, 50kDa
GMPR guanosine monophosphate reductase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2L G patch domain containing 2-like
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H4E histone cluster 1, H4e
HOXC4 homeobox C4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
KIAA0556 KIAA0556
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MFSD11 major facilitator superfamily domain containing 11
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTA2 metastasis associated 1 family, member 2
MUC3A mucin 3A, cell surface associated
NEUROD1 neuronal differentiation 1
NIPAL2 NIPA-like domain containing 2
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
OVOL1 ovo-like zinc finger 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PRB3 proline-rich protein BstNI subfamily 3
PRF1 perforin 1 (pore forming protein)
PROL1 proline rich, lacrimal 1
PRSS53 protease, serine, 53
PTK6 protein tyrosine kinase 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RFXAP regulatory factor X-associated protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIX1 SIX homeobox 1
SLC22A14 solute carrier family 22, member 14
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSBP3 single stranded DNA binding protein 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D19 TBC1 domain family, member 19
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGFBR3 transforming growth factor, beta receptor III
THRAP3 thyroid hormone receptor associated protein 3
TRIM21 tripartite motif containing 21
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
ZBTB48 zinc finger and BTB domain containing 48
ZNF862 zinc finger protein 862