butyl hydroxybenzoate-5245 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the butyl hydroxybenzoate-5245 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMACR alpha-methylacyl-CoA racemase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARTN artemin
ATG10 autophagy related 10
C3 complement component 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CD79B CD79b molecule, immunoglobulin-associated beta
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL1A1 collagen, type I, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CRYGC crystallin, gamma C
CTIF CBP80/20-dependent translation initiation factor
CTNS cystinosin, lysosomal cystine transporter
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DMP1 dentin matrix acidic phosphoprotein 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGR3 early growth response 3
ELMO1 engulfment and cell motility 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EZR ezrin
FAM174B family with sequence similarity 174, member B
FAT4 FAT atypical cadherin 4
FOXG1 forkhead box G1
GPATCH4 G patch domain containing 4
GPC1 glypican 1
GPR182 G protein-coupled receptor 182
GRPR gastrin-releasing peptide receptor
GTDC1 glycosyltransferase-like domain containing 1
HABP2 hyaluronan binding protein 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HES2 hes family bHLH transcription factor 2
HHLA1 HERV-H LTR-associating 1
HPCAL4 hippocalcin like 4
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA10 interferon, alpha 10
IFT27 intraflagellar transport 27
IL11 interleukin 11
INO80D INO80 complex subunit D
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDR kinase insert domain receptor
KLHDC8A kelch domain containing 8A
KRT15 keratin 15, type I
KRT2 keratin 2, type II
KRT31 keratin 31, type I
LECT1 leukocyte cell derived chemotaxin 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED16 mediator complex subunit 16
MTMR7 myotubularin related protein 7
MX1 MX dynamin-like GTPase 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NOP16 NOP16 nucleolar protein
NOX3 NADPH oxidase 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRAP nebulin-related anchoring protein
OASL 2'-5'-oligoadenylate synthetase-like
OXCT2 3-oxoacid CoA transferase 2
PGR progesterone receptor
PTAFR platelet-activating factor receptor
PTGES prostaglandin E synthase
RAB3B RAB3B, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40C RAB40C, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL5 RecQ protein-like 5
RGS12 regulator of G-protein signaling 12
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC3 syndecan 3
SH2D3A SH2 domain containing 3A
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNCAIP synuclein, alpha interacting protein
SOCS3 suppressor of cytokine signaling 3
SP100 SP100 nuclear antigen
SPAG8 sperm associated antigen 8
SPTBN1 spectrin, beta, non-erythrocytic 1
T T, brachyury homolog (mouse)
TAAR5 trace amine associated receptor 5
TBKBP1 TBK1 binding protein 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
UPK3B uroplakin 3B
VN1R1 vomeronasal 1 receptor 1
WAPAL wings apart-like homolog (Drosophila)
WDR55 WD repeat domain 55
ZFP64 ZFP64 zinc finger protein
ZNF234 zinc finger protein 234
ZNF343 zinc finger protein 343
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALPK1 alpha-kinase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BPGM 2,3-bisphosphoglycerate mutase
BTF3P12 basic transcription factor 3 pseudogene 12
C9ORF91 chromosome 9 open reading frame 91
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPG capping protein (actin filament), gelsolin-like
CCDC53 coiled-coil domain containing 53
CCDC9 coiled-coil domain containing 9
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CYB5R1 cytochrome b5 reductase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGKD diacylglycerol kinase, delta 130kDa
DPY19L1P1 DPY19L1 pseudogene 1
EPHA2 EPH receptor A2
FBXL12 F-box and leucine-rich repeat protein 12
FFAR2 free fatty acid receptor 2
FPGT fucose-1-phosphate guanylyltransferase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLI3 GLI family zinc finger 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIST2H2AA3 histone cluster 2, H2aa3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
INPP5F inositol polyphosphate-5-phosphatase F
ITPKB inositol-trisphosphate 3-kinase B
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLF2 Kruppel-like factor 2
LGALS3 lectin, galactoside-binding, soluble, 3
LINC00597 long intergenic non-protein coding RNA 597
LOC730101 uncharacterized LOC730101
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MELK maternal embryonic leucine zipper kinase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRPL44 mitochondrial ribosomal protein L44
NIPAL2 NIPA-like domain containing 2
NKRF NFKB repressing factor
PARD6A par-6 family cell polarity regulator alpha
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDIA3 protein disulfide isomerase family A, member 3
PGS1 phosphatidylglycerophosphate synthase 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
POMT2 protein-O-mannosyltransferase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARS arginyl-tRNA synthetase
RIC8B RIC8 guanine nucleotide exchange factor B
RPA2 replication protein A2, 32kDa
SENP7 SUMO1/sentrin specific peptidase 7
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SOX12 SRY (sex determining region Y)-box 12
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TBC1D31 TBC1 domain family, member 31
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS3 thrombospondin 3
THEM6 thioesterase superfamily member 6
TMEM2 transmembrane protein 2
TMEM53 transmembrane protein 53
TMEM62 transmembrane protein 62
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TULP4 tubby like protein 4
UBXN6 UBX domain protein 6
UNKL unkempt family zinc finger-like
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF250 zinc finger protein 250
ZNF302 zinc finger protein 302
ZNF329 zinc finger protein 329
ZNF571 zinc finger protein 571
ZNF652 zinc finger protein 652
ZNF750 zinc finger protein 750
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862