buflomedil-4840 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the buflomedil-4840 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADRA1D adrenoceptor alpha 1D
AMPD1 adenosine monophosphate deaminase 1
AMPH amphiphysin
ANGPTL2 angiopoietin-like 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ASIC4 acid sensing (proton gated) ion channel family member 4
BAIAP3 BAI1-associated protein 3
BBC3 BCL2 binding component 3
BIRC7 baculoviral IAP repeat containing 7
C14ORF1 chromosome 14 open reading frame 1
C22ORF46 chromosome 22 open reading frame 46
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CD52 CD52 molecule
CDH18 cadherin 18, type 2
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELF2 CUGBP, Elav-like family member 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL5A2 collagen, type V, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCTN1 dynactin 1
DLK1 delta-like 1 homolog (Drosophila)
DOK2 docking protein 2, 56kDa
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FFAR2 free fatty acid receptor 2
FGF2 fibroblast growth factor 2 (basic)
FGF6 fibroblast growth factor 6
FRMPD1 FERM and PDZ domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAP43 growth associated protein 43
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GREB1L growth regulation by estrogen in breast cancer-like
GSAP gamma-secretase activating protein
HAND1 heart and neural crest derivatives expressed 1
HBS1L HBS1-like translational GTPase
HEG1 heart development protein with EGF-like domains 1
HIST1H2AI histone cluster 1, H2ai
HIST1H3A histone cluster 1, H3a
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGN5 high mobility group nucleosome binding domain 5
HOXA4 homeobox A4
ING2 inhibitor of growth family, member 2
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLF6 Kruppel-like factor 6
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KYNU kynureninase
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MAPRE2 microtubule-associated protein, RP/EB family, member 2
METTL7A methyltransferase like 7A
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MTMR8 myotubularin related protein 8
MYL10 myosin, light chain 10, regulatory
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCSK6 proprotein convertase subtilisin/kexin type 6
PEG10 paternally expressed 10
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
POU6F1 POU class 6 homeobox 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRB1 proline-rich protein BstNI subfamily 1
PRKCH protein kinase C, eta
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PXDC1 PX domain containing 1
RIMS2 regulating synaptic membrane exocytosis 2
RTEL1 regulator of telomere elongation helicase 1
RUNX3 runt-related transcription factor 3
SAA4 serum amyloid A4, constitutive
SERHL2 serine hydrolase-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIX2 SIX homeobox 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD6 SMAD family member 6
SP1 Sp1 transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UBOX5 U-box domain containing 5
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UROD uroporphyrinogen decarboxylase
WDTC1 WD and tetratricopeptide repeats 1
WNT6 wingless-type MMTV integration site family, member 6
YIPF4 Yip1 domain family, member 4
ZNF154 zinc finger protein 154
ZNF286A zinc finger protein 286A
ZNF609 zinc finger protein 609
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ACSF2 acyl-CoA synthetase family member 2
ADM adrenomedullin
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB1 arrestin, beta 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C11ORF68 chromosome 11 open reading frame 68
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CENPJ centromere protein J
CIR1 corepressor interacting with RBPJ, 1
CLDN15 claudin 15
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNN2 calponin 2
COL4A5 collagen, type IV, alpha 5
CORO7 coronin 7
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHODH dihydroorotate dehydrogenase (quinone)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENO2 enolase 2 (gamma, neuronal)
ERO1L ERO1-like (S. cerevisiae)
FADS2 fatty acid desaturase 2
FAM63A family with sequence similarity 63, member A
FCHO1 FCH domain only 1
FGGY FGGY carbohydrate kinase domain containing
FKBP10 FK506 binding protein 10, 65 kDa
FMO4 flavin containing monooxygenase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HDAC11 histone deacetylase 11
HIST1H2BJ histone cluster 1, H2bj
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
KLF13 Kruppel-like factor 13
KLF2 Kruppel-like factor 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIN7B lin-7 homolog B (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
MEFV Mediterranean fever
MPDU1 mannose-P-dolichol utilization defect 1
MSMB microseminoprotein, beta-
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NLK nemo-like kinase
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB8 protocadherin beta 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
PODXL2 podocalyxin-like 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PYCRL pyrroline-5-carboxylate reductase-like
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A9 solute carrier family 12, member 9
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPATA7 spermatogenesis associated 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TDRD7 tudor domain containing 7
TGS1 trimethylguanosine synthase 1
TLN1 talin 1
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
TTC4 tetratricopeptide repeat domain 4
UBIAD1 UbiA prenyltransferase domain containing 1
URM1 ubiquitin related modifier 1
YIPF5 Yip1 domain family, member 5
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF552 zinc finger protein 552