bufexamac-7413 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the bufexamac-7413 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADAP1 ArfGAP with dual PH domains 1
ADM2 adrenomedullin 2
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP17A A kinase (PRKA) anchor protein 17A
ANGPTL2 angiopoietin-like 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATF7IP activating transcription factor 7 interacting protein
ATN1 atrophin 1
BAHD1 bromo adjacent homology domain containing 1
BBS9 Bardet-Biedl syndrome 9
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCL22 chemokine (C-C motif) ligand 22
CD47 CD47 molecule
CD6 CD6 molecule
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN1 claudin 1
CNGB3 cyclic nucleotide gated channel beta 3
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCAF4 DDB1 and CUL4 associated factor 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
DST dystonin
DUSP13 dual specificity phosphatase 13
ESRRA estrogen-related receptor alpha
FAM214B family with sequence similarity 214, member B
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF4 fibroblast growth factor 4
FGFR4 fibroblast growth factor receptor 4
FOXO1 forkhead box O1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GM2A GM2 ganglioside activator
GOLGA2 golgin A2
GOSR2 golgi SNAP receptor complex member 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HFE hemochromatosis
HSPA12A heat shock 70kDa protein 12A
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIAA1109 KIAA1109
KIF3C kinesin family member 3C
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
KLHL26 kelch-like family member 26
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPK8 mitogen-activated protein kinase 8
MAST2 microtubule associated serine/threonine kinase 2
NAAA N-acylethanolamine acid amidase
NELL2 NEL-like 2 (chicken)
NIPAL2 NIPA-like domain containing 2
PADI1 peptidyl arginine deiminase, type I
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB8 protocadherin beta 8
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
POU4F1 POU class 4 homeobox 1
PTBP3 polypyrimidine tract binding protein 3
PVR poliovirus receptor
PVRL3 poliovirus receptor-related 3
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RANBP3 RAN binding protein 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGPL1 sphingosine-1-phosphate lyase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD1 SMAD family member 1
SPDEF SAM pointed domain containing ETS transcription factor
SPPL2B signal peptide peptidase like 2B
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK4 serine/threonine kinase 4
SULT4A1 sulfotransferase family 4A, member 1
TGM2 transglutaminase 2
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TOM1 target of myb1 (chicken)
TPP2 tripeptidyl peptidase II
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM36 tripartite motif containing 36
TRIM52 tripartite motif containing 52
TTC28 tetratricopeptide repeat domain 28
ULBP2 UL16 binding protein 2
USP34 ubiquitin specific peptidase 34
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VLDLR very low density lipoprotein receptor
ZNF141 zinc finger protein 141

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABLIM3 actin binding LIM protein family, member 3
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AP3M2 adaptor-related protein complex 3, mu 2 subunit
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF basic leucine zipper transcription factor, ATF-like
BCL2L2 BCL2-like 2
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
CAMTA2 calmodulin binding transcription activator 2
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CASD1 CAS1 domain containing 1
CCDC15 coiled-coil domain containing 15
CDC7 cell division cycle 7
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
COL9A2 collagen, type IX, alpha 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRABP1 cellular retinoic acid binding protein 1
CUEDC1 CUE domain containing 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS3 dehydrogenase/reductase (SDR family) member 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM192A family with sequence similarity 192, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAB2 GRB2-associated binding protein 2
GMPPA GDP-mannose pyrophosphorylase A
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRB7 growth factor receptor-bound protein 7
GSTT1 glutathione S-transferase theta 1
HIRIP3 HIRA interacting protein 3
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HOXC11 homeobox C11
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KATNBL1 katanin p80 subunit B-like 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
MARC1 mitochondrial amidoxime reducing component 1
MYO1E myosin IE
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NRSN2 neurensin 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUPL2 nucleoporin like 2
OGFRL1 opioid growth factor receptor-like 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PER3 period circadian clock 3
PEX26 peroxisomal biogenesis factor 26
PLEK2 pleckstrin 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PP14571 uncharacterized LOC100130449
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPRG protein tyrosine phosphatase, receptor type, G
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB32 RAB32, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFTN1 raftlin, lipid raft linker 1
RNF121 ring finger protein 121
RRP1 ribosomal RNA processing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCD5 stearoyl-CoA desaturase 5
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SIRT2 sirtuin 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNIP1 Smad nuclear interacting protein 1
SOX3 SRY (sex determining region Y)-box 3
SPATA20 spermatogenesis associated 20
TCTA T-cell leukemia translocation altered
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM187 transmembrane protein 187
TMEM254 transmembrane protein 254
TNRC6B trinucleotide repeat containing 6B
TRABD TraB domain containing
TRAPPC2 trafficking protein particle complex 2
TRIOBP TRIO and F-actin binding protein
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
TXLNA taxilin alpha
UBQLN4 ubiquilin 4
USP6NL USP6 N-terminal like
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX3 zinc finger homeobox 3
ZMAT5 zinc finger, matrin-type 5
ZNF23 zinc finger protein 23
ZNHIT2 zinc finger, HIT-type containing 2