bucladesine-2741 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bucladesine-2741 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADRA1A adrenoceptor alpha 1A
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ASPH aspartate beta-hydroxylase
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C21ORF62 chromosome 21 open reading frame 62
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CALD1 caldesmon 1
CAPN6 calpain 6
CCDC92 coiled-coil domain containing 92
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLEC10A C-type lectin domain family 10, member A
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAH17 dynein, axonemal, heavy chain 17
DPP4 dipeptidyl-peptidase 4
EN1 engrailed homeobox 1
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
GPR3 G protein-coupled receptor 3
GRM4 glutamate receptor, metabotropic 4
HAPLN1 hyaluronan and proteoglycan link protein 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA6 homeobox A6
HOXD10 homeobox D10
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IQCK IQ motif containing K
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KSR1 kinase suppressor of ras 1
LEP leptin
LMF1 lipase maturation factor 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
MASP2 mannan-binding lectin serine peptidase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPS18C mitochondrial ribosomal protein S18C
MTMR7 myotubularin related protein 7
NCOR2 nuclear receptor corepressor 2
NPY neuropeptide Y
NRG1 neuregulin 1
NRP1 neuropilin 1
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHB17P protocadherin beta 17 pseudogene
PDE4DIP phosphodiesterase 4D interacting protein
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKD2L2 polycystic kidney disease 2-like 2
PLCE1 phospholipase C, epsilon 1
POU6F2 POU class 6 homeobox 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PROL1 proline rich, lacrimal 1
RAPSN receptor-associated protein of the synapse
RBPMS RNA binding protein with multiple splicing
RHO rhodopsin
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC17A4 solute carrier family 17, member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMC1A structural maintenance of chromosomes 1A
SMR3B submaxillary gland androgen regulated protein 3B
SOX14 SRY (sex determining region Y)-box 14
SPAG8 sperm associated antigen 8
SPRR2B small proline-rich protein 2B
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX1 synovial sarcoma, X breakpoint 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STXBP6 syntaxin binding protein 6 (amisyn)
SYT5 synaptotagmin V
THBS1 thrombospondin 1
TNP2 transition protein 2 (during histone to protamine replacement)
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRGV5 T cell receptor gamma variable 5
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSPYL5 TSPY-like 5
UBE3A ubiquitin protein ligase E3A
VWA1 von Willebrand factor A domain containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF415 zinc finger protein 415
ZNF44 zinc finger protein 44
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD55 ankyrin repeat domain 55
ARMCX4 armadillo repeat containing, X-linked 4
ARRB1 arrestin, beta 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAK1 BCL2-antagonist/killer 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BOLA1 bolA family member 1
C17ORF53 chromosome 17 open reading frame 53
C5ORF30 chromosome 5 open reading frame 30
CCDC85C coiled-coil domain containing 85C
CD300C CD300c molecule
CEP295 centrosomal protein 295kDa
CEP70 centrosomal protein 70kDa
CES3 carboxylesterase 3
CHM choroideremia (Rab escort protein 1)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CTC1 CTS telomere maintenance complex component 1
DCAF13 DDB1 and CUL4 associated factor 13
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS11 dehydrogenase/reductase (SDR family) member 11
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
F13A1 coagulation factor XIII, A1 polypeptide
FAM127B family with sequence similarity 127, member B
FBXO22 F-box protein 22
FKBP9 FK506 binding protein 9, 63 kDa
FOXO4 forkhead box O4
GAS2 growth arrest-specific 2
GBP2 guanylate binding protein 2, interferon-inducible
GK3P glycerol kinase 3 pseudogene
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC9 histone deacetylase 9
HIST1H1E histone cluster 1, H1e
INCENP inner centromere protein antigens 135/155kDa
KCTD20 potassium channel tetramerization domain containing 20
KIAA1107 KIAA1107
LIMD2 LIM domain containing 2
LIN7A lin-7 homolog A (C. elegans)
LOC257152 uncharacterized LOC257152
LRP5 low density lipoprotein receptor-related protein 5
LRRK1 leucine-rich repeat kinase 1
LTBP3 latent transforming growth factor beta binding protein 3
MAGEH1 melanoma antigen family H1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBIP MAP3K12 binding inhibitory protein 1
MDM4 MDM4, p53 regulator
METTL1 methyltransferase like 1
NBEA neurobeachin
NCALD neurocalcin delta
NFE2L3 nuclear factor, erythroid 2-like 3
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIR pirin (iron-binding nuclear protein)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PMFBP1 polyamine modulated factor 1 binding protein 1
PODXL2 podocalyxin-like 2
POU5F1B POU class 5 homeobox 1B
PRDM1 PR domain containing 1, with ZNF domain
PRR4 proline rich 4 (lacrimal)
QTRT1 queuine tRNA-ribosyltransferase 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOB ras homolog family member B
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RRAGB Ras-related GTP binding B
SCG5 secretogranin V
SERINC5 serine incorporator 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGMS1 sphingomyelin synthase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2D4A SH2 domain containing 4A
SLC16A4 solute carrier family 16, member 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPRYD7 SPRY domain containing 7
STX1A syntaxin 1A (brain)
SYCP2 synaptonemal complex protein 2
TBXAS1 thromboxane A synthase 1 (platelet)
TMEM242 transmembrane protein 242
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TP53I3 tumor protein p53 inducible protein 3
TRIM25 tripartite motif containing 25
TTC23 tetratricopeptide repeat domain 23
TWISTNB TWIST neighbor
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP6NL USP6 N-terminal like
WASF3 WAS protein family, member 3
WDR62 WD repeat domain 62
ZNF177 zinc finger protein 177
ZNF473 zinc finger protein 473
ZNF492 zinc finger protein 492
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778