bronchial smooth muscle Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Smooth muscle that is present continuously around the bronchi. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004401)
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Genes

168 proteins co-occuring with the tissue bronchial smooth muscle in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ADAM33 ADAM metallopeptidase domain 33 1.63606
TAC1 tachykinin, precursor 1 1.58043
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.44868
MYLK myosin light chain kinase 1.29489
EDN1 endothelin 1 1.28547
IL13 interleukin 13 1.25012
MME membrane metallo-endopeptidase 1.22247
EDNRA endothelin receptor type A 1.17757
TACR2 tachykinin receptor 2 1.17358
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.15628
NPS neuropeptide S 1.0775
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.02425
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.979783
VIP vasoactive intestinal peptide 0.954703
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.934054
KNG1 kininogen 1 0.908387
ADCY6 adenylate cyclase 6 0.890525
CALCA calcitonin-related polypeptide alpha 0.889678
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.835318
PDE4A phosphodiesterase 4A, cAMP-specific 0.824013
ADRB2 adrenoceptor beta 2, surface 0.803544
CLCN4 chloride channel, voltage-sensitive 4 0.801876
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.795624
TBXA2R thromboxane A2 receptor 0.794375
CSN3 casein kappa 0.79146
NOSIP nitric oxide synthase interacting protein 0.783557
CALR calreticulin 0.782725
EDN3 endothelin 3 0.750818
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.750405
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.747927
CCL11 chemokine (C-C motif) ligand 11 0.745451
MYH11 myosin, heavy chain 11, smooth muscle 0.73062
ADORA2B adenosine A2b receptor 0.72733
RGS5 regulator of G-protein signaling 5 0.726918
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.724863
LTC4S leukotriene C4 synthase 0.700671
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.699853
CMA1 chymase 1, mast cell 0.687184
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.683919
ORAI1 ORAI calcium release-activated calcium modulator 1 0.673728
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.668843
TACR1 tachykinin receptor 1 0.663149
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.64529
ACHE acetylcholinesterase (Yt blood group) 0.626677
STIM1 stromal interaction molecule 1 0.615377
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.606514
NEUROD1 neuronal differentiation 1 0.599273
C3AR1 complement component 3a receptor 1 0.590437
HBE1 hemoglobin, epsilon 1 0.573616
CYSLTR2 cysteinyl leukotriene receptor 2 0.57042
LSM1 LSM1, U6 small nuclear RNA associated 0.561644
IL1B interleukin 1, beta 0.550901
CXCL5 chemokine (C-X-C motif) ligand 5 0.544152
MYL9 myosin, light chain 9, regulatory 0.527534
GRP gastrin-releasing peptide 0.526744
TAGLN transgelin 0.523194
TNF tumor necrosis factor 0.522011
FRK fyn-related Src family tyrosine kinase 0.518072
EDNRB endothelin receptor type B 0.504318
KIAA0101 KIAA0101 0.503533
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.496483
EIF4E eukaryotic translation initiation factor 4E 0.492963
CTF1 cardiotrophin 1 0.48087
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.476201
IL4 interleukin 4 0.464174
CKLF chemokine-like factor 0.462239
JAK1 Janus kinase 1 0.455284
CLCN1 chloride channel, voltage-sensitive 1 0.441042
CLCN2 chloride channel, voltage-sensitive 2 0.43989
TGFB1 transforming growth factor, beta 1 0.437972
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.436438
HRH2 histamine receptor H2 0.434906
CLCN6 chloride channel, voltage-sensitive 6 0.429547
CLNK cytokine-dependent hematopoietic cell linker 0.426109
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.420766
TP63 tumor protein p63 0.418861
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.417337
ADGRL4 adhesion G protein-coupled receptor L4 0.416195
CCL7 chemokine (C-C motif) ligand 7 0.409731
TYK2 tyrosine kinase 2 0.391931
RND3 Rho family GTPase 3 0.390044
ADCY2 adenylate cyclase 2 (brain) 0.387404
CYSLTR1 cysteinyl leukotriene receptor 1 0.383637
CAV1 caveolin 1, caveolae protein, 22kDa 0.381755
NPY neuropeptide Y 0.380627
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.376494
NKX2-1 NK2 homeobox 1 0.372369
LAMB2 laminin, beta 2 (laminin S) 0.371245
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.37087
C5AR1 complement component 5a receptor 1 0.369747
EHF ets homologous factor 0.365633
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.359664
HRH1 histamine receptor H1 0.359664
ELF5 E74-like factor 5 (ets domain transcription factor) 0.356686
HES1 hes family bHLH transcription factor 1 0.354826
CCL26 chemokine (C-C motif) ligand 26 0.35334
FOXF1 forkhead box F1 0.34926
BCHE butyrylcholinesterase 0.346668
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.345928
ELOVL6 ELOVL fatty acid elongase 6 0.34334
CASQ2 calsequestrin 2 (cardiac muscle) 0.342971
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.340388
NPSR1 neuropeptide S receptor 1 0.336704
GPR135 G protein-coupled receptor 135 0.334498
RNASE3 ribonuclease, RNase A family, 3 0.333396
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.325335
CLCN5 chloride channel, voltage-sensitive 5 0.309335
ILK integrin-linked kinase 0.306805
ACTB actin, beta 0.30464
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.299242
JAK3 Janus kinase 3 0.297089
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.296372
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.294581
PI3 peptidase inhibitor 3, skin-derived 0.293508
TSLP thymic stromal lymphopoietin 0.287092
MMP12 matrix metallopeptidase 12 0.278603
ADGRE5 adhesion G protein-coupled receptor E5 0.275794
CCL24 chemokine (C-C motif) ligand 24 0.269521
CTGF connective tissue growth factor 0.265038
MYLK3 myosin light chain kinase 3 0.257572
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.250953
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.250627
ADCY3 adenylate cyclase 3 0.249653
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.249653
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.24486
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.242672
PDIA3 protein disulfide isomerase family A, member 3 0.236921
PCNA proliferating cell nuclear antigen 0.229032
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.229032
NRF1 nuclear respiratory factor 1 0.226155
CLCN3 chloride channel, voltage-sensitive 3 0.218613
TBXAS1 thromboxane A synthase 1 (platelet) 0.215928
S1PR3 sphingosine-1-phosphate receptor 3 0.215147
RFC2 replication factor C (activator 1) 2, 40kDa 0.214954
KLF5 Kruppel-like factor 5 (intestinal) 0.214202
PDGFC platelet derived growth factor C 0.213833
S1PR2 sphingosine-1-phosphate receptor 2 0.213291
SUMF2 sulfatase modifying factor 2 0.197051
IL16 interleukin 16 0.197012
CCL5 chemokine (C-C motif) ligand 5 0.196953
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.196698
RGS4 regulator of G-protein signaling 4 0.19634
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.196074
ANO1 anoctamin 1, calcium activated chloride channel 0.195585
PDGFA platelet-derived growth factor alpha polypeptide 0.19553
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.195122
CCL13 chemokine (C-C motif) ligand 13 0.194801
TLR3 toll-like receptor 3 0.194542
IL6 interleukin 6 0.194504
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.194011
FGF2 fibroblast growth factor 2 (basic) 0.193794
NTF3 neurotrophin 3 0.193767
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.193753
FKBP1A FK506 binding protein 1A, 12kDa 0.193739
ZHX2 zinc fingers and homeoboxes 2 0.193358
CCL8 chemokine (C-C motif) ligand 8 0.193227
SCN3A sodium channel, voltage gated, type III alpha subunit 0.192823
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.192481
MAP2K1 mitogen-activated protein kinase kinase 1 0.192272
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.192059
TPI1 triosephosphate isomerase 1 0.191858
RTN4 reticulon 4 0.191444
FBL fibrillarin 0.191159
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.191013
PTAFR platelet-activating factor receptor 0.190734
CXCL8 chemokine (C-X-C motif) ligand 8 0.19062
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.190271
KAT5 K(lysine) acetyltransferase 5 0.189808