brompheniramine-4131 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the brompheniramine-4131 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADCK2 aarF domain containing kinase 2
ADGRL1 adhesion G protein-coupled receptor L1
ADRA1A adrenoceptor alpha 1A
AGMAT agmatine ureohydrolase (agmatinase)
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
AMPD1 adenosine monophosphate deaminase 1
AMPD3 adenosine monophosphate deaminase 3
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ASPH aspartate beta-hydroxylase
BIRC3 baculoviral IAP repeat containing 3
C1ORF95 chromosome 1 open reading frame 95
C5ORF42 chromosome 5 open reading frame 42
CDC25C cell division cycle 25C
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CLCA2 chloride channel accessory 2
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMXL2 Dmx-like 2
DTX2 deltex 2, E3 ubiquitin ligase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNB3 ephrin-B3
ERP44 endoplasmic reticulum protein 44
ETV5 ets variant 5
EXOSC2 exosome component 2
EXT1 exostosin glycosyltransferase 1
FANCA Fanconi anemia, complementation group A
FKBP8 FK506 binding protein 8, 38kDa
FLOT1 flotillin 1
FSCN3 fascin actin-bundling protein 3, testicular
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GPR143 G protein-coupled receptor 143
GTPBP1 GTP binding protein 1
HBEGF heparin-binding EGF-like growth factor
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HRH1 histamine receptor H1
HSPG2 heparan sulfate proteoglycan 2
ICA1 islet cell autoantigen 1, 69kDa
IL18 interleukin 18
IL1B interleukin 1, beta
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA1107 KIAA1107
KIAA1109 KIAA1109
KMT2A lysine (K)-specific methyltransferase 2A
LINC00216 long intergenic non-protein coding RNA 216
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP12 low density lipoprotein receptor-related protein 12
LRRC37A3 leucine rich repeat containing 37, member A3
MAL mal, T-cell differentiation protein
MC5R melanocortin 5 receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2D myocyte enhancer factor 2D
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MTMR1 myotubularin related protein 1
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
N4BP2L1 NEDD4 binding protein 2-like 1
NPC1 Niemann-Pick disease, type C1
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NRN1 neuritin 1
NTM neurotrimin
NTS neurotensin
OMG oligodendrocyte myelin glycoprotein
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARP11 poly (ADP-ribose) polymerase family, member 11
PCDHGA8 protocadherin gamma subfamily A, 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PLAC4 placenta-specific 4
PML promyelocytic leukemia
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RASIP1 Ras interacting protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3BP2 SH3-domain binding protein 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUGP1 SURP and G patch domain containing 1
TBC1D22A TBC1 domain family, member 22A
TMPRSS2 transmembrane protease, serine 2
UHRF1BP1L UHRF1 binding protein 1-like
VWA5A von Willebrand factor A domain containing 5A
ZBED4 zinc finger, BED-type containing 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
C1QB complement component 1, q subcomponent, B chain
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCA1 chloride channel accessory 1
CPA4 carboxypeptidase A4
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FGF23 fibroblast growth factor 23
FOXN2 forkhead box N2
GADD45G growth arrest and DNA-damage-inducible, gamma
GRIP2 glutamate receptor interacting protein 2
HDAC11 histone deacetylase 11
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H4A histone cluster 1, H4a
HOXA4 homeobox A4
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IBSP integrin-binding sialoprotein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP5J inositol polyphosphate-5-phosphatase J
IQSEC2 IQ motif and Sec7 domain 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF5A kinesin family member 5A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT31 keratin 31, type I
LEFTY2 left-right determination factor 2
LIN7B lin-7 homolog B (C. elegans)
LPPR1 lipid phosphate phosphatase-related protein type 1
LTBP2 latent transforming growth factor beta binding protein 2
LTC4S leukotriene C4 synthase
MMP3 matrix metallopeptidase 3
MRPL41 mitochondrial ribosomal protein L41
MST1R macrophage stimulating 1 receptor
NACA2 nascent polypeptide-associated complex alpha subunit 2
NELL2 NEL-like 2 (chicken)
NKX3-2 NK3 homeobox 2
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGB6 protocadherin gamma subfamily B, 6
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRAMEF11 PRAME family member 11
PRF1 perforin 1 (pore forming protein)
PROL1 proline rich, lacrimal 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFXAP regulatory factor X-associated protein
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPL10L ribosomal protein L10-like
RPL13P5 ribosomal protein L13 pseudogene 5
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC17A2 solute carrier family 17, member 2
SLC35F6 solute carrier family 35, member F6
SPTBN2 spectrin, beta, non-erythrocytic 2
STRA6 stimulated by retinoic acid 6
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCTN2 tectonic family member 2
THRAP3 thyroid hormone receptor associated protein 3
TM4SF4 transmembrane 4 L six family member 4
UCN urocortin
UNC119 unc-119 homolog (C. elegans)
VEGFB vascular endothelial growth factor B
WDR78 WD repeat domain 78
ZNF280A zinc finger protein 280A