brompheniramine-4013 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the brompheniramine-4013 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADD2 adducin 2 (beta)
AMPH amphiphysin
AOAH acyloxyacyl hydrolase (neutrophil)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ASIC4 acid sensing (proton gated) ion channel family member 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BEND5 BEN domain containing 5
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCL2 chemokine (C-C motif) ligand 2
CD82 CD82 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP162 centrosomal protein 162kDa
CHM choroideremia (Rab escort protein 1)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DIO3 deiodinase, iodothyronine, type III
DST dystonin
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EML2 echinoderm microtubule associated protein like 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPHA5 EPH receptor A5
FAM162A family with sequence similarity 162, member A
GFRA1 GDNF family receptor alpha 1
GNRHR gonadotropin-releasing hormone receptor
GSK3A glycogen synthase kinase 3 alpha
HIPK3 homeodomain interacting protein kinase 3
HPS1 Hermansky-Pudlak syndrome 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL6 interleukin 6
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0391 KIAA0391
KIF1C kinesin family member 1C
KRT23 keratin 23, type I
KRT9 keratin 9, type I
LDB1 LIM domain binding 1
LDB2 LIM domain binding 2
LINC00652 long intergenic non-protein coding RNA 652
LRRN3 leucine rich repeat neuronal 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL20 mitochondrial ribosomal protein L20
MTMR3 myotubularin related protein 3
N4BP2L2 NEDD4 binding protein 2-like 2
NEFM neurofilament, medium polypeptide
NF1 neurofibromin 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PBX2 pre-B-cell leukemia homeobox 2
PCNXL2 pecanex-like 2 (Drosophila)
PGM5 phosphoglucomutase 5
PHTF2 putative homeodomain transcription factor 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGR polymeric immunoglobulin receptor
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKN2 protein kinase N2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCI protein kinase C, iota
PRY PTPN13-like, Y-linked
PTBP3 polypyrimidine tract binding protein 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOBTB3 Rho-related BTB domain containing 3
RXRB retinoid X receptor, beta
RYK receptor-like tyrosine kinase
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC14L5 SEC14-like 5 (S. cerevisiae)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLMO1 slowmo homolog 1 (Drosophila)
SRSF5 serine/arginine-rich splicing factor 5
SUSD5 sushi domain containing 5
SYCP2 synaptonemal complex protein 2
TBX2 T-box 2
THBD thrombomodulin
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNS1 tensin 1
TPP1 tripeptidyl peptidase I
TRAPPC9 trafficking protein particle complex 9
TRIM3 tripartite motif containing 3
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSPAN8 tetraspanin 8
TTLL4 tubulin tyrosine ligase-like family member 4
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XIST X inactive specific transcript (non-protein coding)
ZFHX2 zinc finger homeobox 2
ZNF391 zinc finger protein 391
ZNF639 zinc finger protein 639
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ALOX12 arachidonate 12-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ARMCX4 armadillo repeat containing, X-linked 4
B9D2 B9 protein domain 2
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
C5ORF42 chromosome 5 open reading frame 42
CA9 carbonic anhydrase IX
CAPN15 calpain 15
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CHI3L2 chitinase 3-like 2
CHKB choline kinase beta
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNR2 cannabinoid receptor 2 (macrophage)
COL9A3 collagen, type IX, alpha 3
CORO2B coronin, actin binding protein, 2B
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDN dendrin
DENND2D DENN/MADD domain containing 2D
DNAH17 dynein, axonemal, heavy chain 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EDN1 endothelin 1
ELSPBP1 epididymal sperm binding protein 1
EXOSC1 exosome component 1
FAM204A family with sequence similarity 204, member A
FBXO2 F-box protein 2
FLT4 fms-related tyrosine kinase 4
GLS2 glutaminase 2 (liver, mitochondrial)
GRAMD4 GRAM domain containing 4
GRM4 glutamate receptor, metabotropic 4
GRM6 glutamate receptor, metabotropic 6
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H3A histone cluster 1, H3a
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IFNA14 interferon, alpha 14
IFNA17 interferon, alpha 17
IGLL1 immunoglobulin lambda-like polypeptide 1
INPPL1 inositol polyphosphate phosphatase-like 1
ITGB7 integrin, beta 7
ITPKA inositol-trisphosphate 3-kinase A
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIRREL kin of IRRE like (Drosophila)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
LRRC15 leucine rich repeat containing 15
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAP3K7CL MAP3K7 C-terminal like
MX1 MX dynamin-like GTPase 1
MYO1F myosin IF
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NINL ninein-like
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTSR1 neurotensin receptor 1 (high affinity)
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR5 progestin and adipoQ receptor family member V
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLXNB3 plexin B3
PMCH pro-melanin-concentrating hormone
PRR4 proline rich 4 (lacrimal)
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
S100A3 S100 calcium binding protein A3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLAMF7 SLAM family member 7
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSNAXIP1 translin-associated factor X interacting protein 1
ZNF268 zinc finger protein 268
ZNF37BP zinc finger protein 37B, pseudogene
ZNF528 zinc finger protein 528
ZXDB zinc finger, X-linked, duplicated B