bromopride-4741 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the bromopride-4741 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AJAP1 adherens junctions associated protein 1
AKAP7 A kinase (PRKA) anchor protein 7
ANGPTL2 angiopoietin-like 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BGN biglycan
C17ORF59 chromosome 17 open reading frame 59
CA1 carbonic anhydrase I
CCKAR cholecystokinin A receptor
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHGA chromogranin A
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN17 claudin 17
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL1A1 collagen, type I, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCHS1 dachsous cadherin-related 1
DCLK2 doublecortin-like kinase 2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DMPK dystrophia myotonica-protein kinase
DPF1 D4, zinc and double PHD fingers family 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ETV4 ets variant 4
FABP3 fatty acid binding protein 3, muscle and heart
FRMD8 FERM domain containing 8
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABARAPL1 GABA(A) receptor-associated protein like 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GREB1L growth regulation by estrogen in breast cancer-like
GRPR gastrin-releasing peptide receptor
HAPLN1 hyaluronan and proteoglycan link protein 1
HYAL3 hyaluronoglucosaminidase 3
ISL1 ISL LIM homeobox 1
KIAA0509 uncharacterized LOC57242
KIF1C kinesin family member 1C
KRT14 keratin 14, type I
LAMA4 laminin, alpha 4
LDB3 LIM domain binding 3
LOC284244 uncharacterized LOC284244
LRP12 low density lipoprotein receptor-related protein 12
MEP1B meprin A, beta
MIER2 mesoderm induction early response 1, family member 2
MUSK muscle, skeletal, receptor tyrosine kinase
MXD4 MAX dimerization protein 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NXF2 nuclear RNA export factor 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPCML opioid binding protein/cell adhesion molecule-like
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PBOV1 prostate and breast cancer overexpressed 1
PDGFD platelet derived growth factor D
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLTP phospholipid transfer protein
PRDM14 PR domain containing 14
PSCA prostate stem cell antigen
PTCRA pre T-cell antigen receptor alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB6A RAB6A, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBP4 retinol binding protein 4, plasma
RFPL1 ret finger protein-like 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SATB2 SATB homeobox 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPD surfactant protein D
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SOAT2 sterol O-acyltransferase 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TBC1D2 TBC1 domain family, member 2
TIAM2 T-cell lymphoma invasion and metastasis 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TJAP1 tight junction associated protein 1 (peripheral)
TLX2 T-cell leukemia homeobox 2
TOP3A topoisomerase (DNA) III alpha
TP53I11 tumor protein p53 inducible protein 11
TRIM15 tripartite motif containing 15
VSIG4 V-set and immunoglobulin domain containing 4
WIPI2 WD repeat domain, phosphoinositide interacting 2
YY2 YY2 transcription factor
ZNF440 zinc finger protein 440
ZNF76 zinc finger protein 76
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD10 acyl-CoA dehydrogenase family, member 10
ADM adrenomedullin
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C11ORF30 chromosome 11 open reading frame 30
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC6 coiled-coil domain containing 6
CD8A CD8a molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CGA glycoprotein hormones, alpha polypeptide
CLSTN2 calsyntenin 2
CRYBG3 beta-gamma crystallin domain containing 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
EGFL7 EGF-like-domain, multiple 7
ELSPBP1 epididymal sperm binding protein 1
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FAM155A family with sequence similarity 155, member A
FAM189A2 family with sequence similarity 189, member A2
FBXO5 F-box protein 5
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP10 FK506 binding protein 10, 65 kDa
GAB2 GRB2-associated binding protein 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH2L G patch domain containing 2-like
HIRA histone cell cycle regulator
HIST1H4F histone cluster 1, H4f
IFI6 interferon, alpha-inducible protein 6
INPP1 inositol polyphosphate-1-phosphatase
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM8 lysine (K)-specific demethylase 8
LIN7A lin-7 homolog A (C. elegans)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANBA mannosidase, beta A, lysosomal
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP6D1 MAP6 domain containing 1
MED22 mediator complex subunit 22
MKNK2 MAP kinase interacting serine/threonine kinase 2
MT1H metallothionein 1H
MTCP1 mature T-cell proliferation 1
NCALD neurocalcin delta
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOL12 nucleolar protein 12
NPTX1 neuronal pentraxin I
NT5E 5'-nucleotidase, ecto (CD73)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PCSK7 proprotein convertase subtilisin/kexin type 7
PER3 period circadian clock 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PRPH peripherin
QPCTL glutaminyl-peptide cyclotransferase-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUNDC3B RUN domain containing 3B
SAMD9 sterile alpha motif domain containing 9
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SYBU syntabulin (syntaxin-interacting)
TESK1 testis-specific kinase 1
TH tyrosine hydroxylase
TMC7 transmembrane channel-like 7
TMEM2 transmembrane protein 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
UBTD1 ubiquitin domain containing 1
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF136 zinc finger protein 136
ZNF189 zinc finger protein 189
ZNF329 zinc finger protein 329
ZNF623 zinc finger protein 623
ZNF665 zinc finger protein 665
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2