bromopride-4278 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bromopride-4278 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AADAC arylacetamide deacetylase
ACTN2 actinin, alpha 2
AJAP1 adherens junctions associated protein 1
ANGPTL2 angiopoietin-like 2
ARC activity-regulated cytoskeleton-associated protein
ARHGAP28 Rho GTPase activating protein 28
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARNT aryl hydrocarbon receptor nuclear translocator
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BBC3 BCL2 binding component 3
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
CCL24 chemokine (C-C motif) ligand 24
CD6 CD6 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLDN10 claudin 10
CLPS colipase, pancreatic
CST4 cystatin S
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCLK2 doublecortin-like kinase 2
DCT dopachrome tautomerase
DMRT1 doublesex and mab-3 related transcription factor 1
DRD2 dopamine receptor D2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFCAB6 EF-hand calcium binding domain 6
ELAC2 elaC ribonuclease Z 2
FAM189A2 family with sequence similarity 189, member A2
FAM212B family with sequence similarity 212, member B
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMNL1 formin-like 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GPR17 G protein-coupled receptor 17
GRM2 glutamate receptor, metabotropic 2
HCFC1 host cell factor C1
HFE hemochromatosis
HRH4 histamine receptor H4
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KHK ketohexokinase (fructokinase)
KRTAP2-4 keratin associated protein 2-4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00472 long intergenic non-protein coding RNA 472
MAK male germ cell-associated kinase
MARK2 MAP/microtubule affinity-regulating kinase 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MUC3A mucin 3A, cell surface associated
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEBL nebulette
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
ONECUT2 one cut homeobox 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBP2 oxysterol binding protein 2
PLAG1 pleiomorphic adenoma gene 1
PRB1 proline-rich protein BstNI subfamily 1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRB protein tyrosine phosphatase, receptor type, B
REEP2 receptor accessory protein 2
RGS12 regulator of G-protein signaling 12
RIF1 replication timing regulatory factor 1
RIMS3 regulating synaptic membrane exocytosis 3
RPL23AP53 ribosomal protein L23a pseudogene 53
RUNDC3A RUN domain containing 3A
SCN10A sodium channel, voltage gated, type X alpha subunit
SLAMF7 SLAM family member 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A30 solute carrier family 25, member 30
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD6 SMAD family member 6
SMO smoothened, frizzled class receptor
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPRED2 sprouty-related, EVH1 domain containing 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRRT serrate, RNA effector molecule
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STS steroid sulfatase (microsomal), isozyme S
TADA3 transcriptional adaptor 3
TGM4 transglutaminase 4
THBD thrombomodulin
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE4 transducin-like enhancer of split 4
TMEM259 transmembrane protein 259
VCL vinculin
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZBTB7A zinc finger and BTB domain containing 7A
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANP32A-IT1 ANP32A intronic transcript 1
APH1B APH1B gamma secretase subunit
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG2B autophagy related 2B
ATP7B ATPase, Cu++ transporting, beta polypeptide
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BICC1 BicC family RNA binding protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF70 chromosome 17 open reading frame 70
C1R complement component 1, r subcomponent
CCDC85C coiled-coil domain containing 85C
CENPO centromere protein O
CHMP6 charged multivesicular body protein 6
CNPY3 canopy FGF signaling regulator 3
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAL4 dynein, axonemal, light chain 4
EMP3 epithelial membrane protein 3
ERCC4 excision repair cross-complementation group 4
ERF Ets2 repressor factor
FAM184A family with sequence similarity 184, member A
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBRS fibrosin
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GAMT guanidinoacetate N-methyltransferase
GAS8 growth arrest-specific 8
GLS2 glutaminase 2 (liver, mitochondrial)
GUSBP3 glucuronidase, beta pseudogene 3
H2AFJ H2A histone family, member J
HDAC5 histone deacetylase 5
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H3F histone cluster 1, H3f
HOXC5 homeobox C5
IL22 interleukin 22
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0232 KIAA0232
KLC2 kinesin light chain 2
KLF11 Kruppel-like factor 11
KLHL25 kelch-like family member 25
LOC257152 uncharacterized LOC257152
LRP4 low density lipoprotein receptor-related protein 4
MAGEA6 melanoma antigen family A6
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFGE8 milk fat globule-EGF factor 8 protein
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MOCS3 molybdenum cofactor synthesis 3
MTMR11 myotubularin related protein 11
NABP1 nucleic acid binding protein 1
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
NSUN6 NOP2/Sun domain family, member 6
NTHL1 nth endonuclease III-like 1 (E. coli)
ORC1 origin recognition complex, subunit 1
PDGFRL platelet-derived growth factor receptor-like
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLAC8 placenta-specific 8
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRR14L proline rich 14-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RPL10L ribosomal protein L10-like
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC38A10 solute carrier family 38, member 10
STX17 syntaxin 17
TEX40 testis expressed 40
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPCN1 two pore segment channel 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
WDR25 WD repeat domain 25
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YY2 YY2 transcription factor
ZNF219 zinc finger protein 219
ZNF492 zinc finger protein 492
ZNF639 zinc finger protein 639
ZNF667 zinc finger protein 667
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZW10 zw10 kinetochore protein