bretylium tosilate-6674 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bretylium tosilate-6674 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADCY9 adenylate cyclase 9
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BCL3 B-cell CLL/lymphoma 3
C17ORF53 chromosome 17 open reading frame 53
C8A complement component 8, alpha polypeptide
CACYBP calcyclin binding protein
CALB2 calbindin 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDRT1 CMT1A duplicated region transcript 1
CFAP70 cilia and flagella associated protein 70
CNTNAP2 contactin associated protein-like 2
CUBN cubilin (intrinsic factor-cobalamin receptor)
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPF1 D4, zinc and double PHD fingers family 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FCGBP Fc fragment of IgG binding protein
FILIP1L filamin A interacting protein 1-like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GYPC glycophorin C (Gerbich blood group)
HOXD3 homeobox D3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12B interleukin 12B
ING4 inhibitor of growth family, member 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF13 Kruppel-like factor 13
LRRN3 leucine rich repeat neuronal 3
MAN1A2 mannosidase, alpha, class 1A, member 2
MED25 mediator complex subunit 25
MTA1 metastasis associated 1
N4BP2L1 NEDD4 binding protein 2-like 1
NCAM2 neural cell adhesion molecule 2
NEK1 NIMA-related kinase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOVA2 neuro-oncological ventral antigen 2
NRCAM neuronal cell adhesion molecule
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ONECUT2 one cut homeobox 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PEX5L peroxisomal biogenesis factor 5-like
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF7 PHD finger protein 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD2L2 polycystic kidney disease 2-like 2
PKP1 plakophilin 1
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCQ protein kinase C, theta
PRPH peripherin
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3D RAB3D, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RERE arginine-glutamic acid dipeptide (RE) repeats
RORC RAR-related orphan receptor C
RRAGD Ras-related GTP binding D
SAA3P serum amyloid A3 pseudogene
SARM1 sterile alpha and TIR motif containing 1
SCAND2P SCAN domain containing 2 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEC24D SEC24 family member D
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SNX13 sorting nexin 13
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX1 synovial sarcoma, X breakpoint 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TCEAL2 transcription elongation factor A (SII)-like 2
THY1 Thy-1 cell surface antigen
TIMELESS timeless circadian clock
TLDC1 TBC/LysM-associated domain containing 1
TOP3B topoisomerase (DNA) III beta
TP63 tumor protein p63
TRAPPC9 trafficking protein particle complex 9
TRD T cell receptor delta locus
TRIM48 tripartite motif containing 48
UBXN1 UBX domain protein 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZNF3 zinc finger protein 3
ZXDB zinc finger, X-linked, duplicated B
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATAD5 ATPase family, AAA domain containing 5
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF105 chromosome 14 open reading frame 105
C14ORF93 chromosome 14 open reading frame 93
C1ORF21 chromosome 1 open reading frame 21
C9ORF9 chromosome 9 open reading frame 9
CCDC88C coiled-coil domain containing 88C
CEP131 centrosomal protein 131kDa
CNGB3 cyclic nucleotide gated channel beta 3
CNTLN centlein, centrosomal protein
CPED1 cadherin-like and PC-esterase domain containing 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DLK2 delta-like 2 homolog (Drosophila)
EDAR ectodysplasin A receptor
ERAP2 endoplasmic reticulum aminopeptidase 2
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
GAS8 growth arrest-specific 8
GEMIN8 gem (nuclear organelle) associated protein 8
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC3 glypican 3
GRAMD4 GRAM domain containing 4
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DMB major histocompatibility complex, class II, DM beta
HSF2BP heat shock transcription factor 2 binding protein
IFI44L interferon-induced protein 44-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
KIAA1549L KIAA1549-like
KLK7 kallikrein-related peptidase 7
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIFR leukemia inhibitory factor receptor alpha
LOC100127972 uncharacterized LOC100127972
LOC100286895 cell division cycle 27 homolog pseudogene
LPAR4 lysophosphatidic acid receptor 4
LY6G6C lymphocyte antigen 6 complex, locus G6C
MEGF8 multiple EGF-like-domains 8
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MILR1 mast cell immunoglobulin-like receptor 1
MST1 macrophage stimulating 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PACS1 phosphofurin acidic cluster sorting protein 1
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA1A phospholipase A1 member A
POMT2 protein-O-mannosyltransferase 2
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPRE protein tyrosine phosphatase, receptor type, E
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RPS17P5 ribosomal protein S17 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SEPP1 selenoprotein P, plasma, 1
SGK2 serum/glucocorticoid regulated kinase 2
SHROOM2 shroom family member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TENM1 teneurin transmembrane protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMSB15A thymosin beta 15a
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM21 tripartite motif containing 21
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
TXK TXK tyrosine kinase
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YOD1 YOD1 deubiquitinase
YY2 YY2 transcription factor
ZFP30 ZFP30 zinc finger protein
ZNF141 zinc finger protein 141
ZNF197 zinc finger protein 197
ZNF214 zinc finger protein 214
ZNF41 zinc finger protein 41