breast fibroadenoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A breast benign neoplasm comprised of fibrous and glandoular tissues located_in breast. (Human Disease Ontology, DOID_1618)
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Genes

150 genes co-occuring with the disease breast fibroadenoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PGR progesterone receptor 1.41797
ESR1 estrogen receptor 1 1.3062
ERBB2 erb-b2 receptor tyrosine kinase 2 1.13416
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.977585
CD34 CD34 molecule 0.939119
SYNJ2BP synaptojanin 2 binding protein 0.859362
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.856087
TP53 tumor protein p53 0.844211
KRT15 keratin 15, type I 0.811411
PCNA proliferating cell nuclear antigen 0.788852
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.750457
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.741517
MKI67 marker of proliferation Ki-67 0.720865
KDM4A lysine (K)-specific demethylase 4A 0.695504
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.687891
KRT14 keratin 14, type I 0.676308
KRT8 keratin 8, type II 0.649323
KRT31 keratin 31, type I 0.632384
ESR2 estrogen receptor 2 (ER beta) 0.59991
DOCK4 dedicator of cytokinesis 4 0.59874
ACVR1C activin A receptor, type IC 0.588612
RHEB Ras homolog enriched in brain 0.578494
RAB27B RAB27B, member RAS oncogene family 0.57655
USP22 ubiquitin specific peptidase 22 0.574994
HIC1 hypermethylated in cancer 1 0.571495
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.545868
F8 coagulation factor VIII, procoagulant component 0.543542
PRL prolactin 0.533861
PIP prolactin-induced protein 0.530381
GREM2 gremlin 2, DAN family BMP antagonist 0.528835
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.521117
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.514571
EFNA3 ephrin-A3 0.512264
EGFR epidermal growth factor receptor 0.510728
KRT7 keratin 7, type II 0.505356
PZP pregnancy-zone protein 0.504973
LAMA5 laminin, alpha 5 0.495029
WEE1 WEE1 G2 checkpoint kinase 0.486646
CLDN6 claudin 6 0.484744
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.466172
KRT5 keratin 5, type II 0.465416
PELP1 proline, glutamate and leucine rich protein 1 0.463149
AR androgen receptor 0.455224
MMP2 matrix metallopeptidase 2 0.454093
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.449194
A1BG alpha-1-B glycoprotein 0.447311
PLVAP plasmalemma vesicle associated protein 0.439034
CALR calreticulin 0.435275
NMU neuromedin U 0.432646
HDAC1 histone deacetylase 1 0.431894
AMHR2 anti-Mullerian hormone receptor, type II 0.429642
VASH1 vasohibin 1 0.425514
WIBG within bgcn homolog (Drosophila) 0.420266
GRIK4 glutamate receptor, ionotropic, kainate 4 0.418394
DIO1 deiodinase, iodothyronine, type I 0.416521
MFGE8 milk fat globule-EGF factor 8 protein 0.406798
RARB retinoic acid receptor, beta 0.391141
FAP fibroblast activation protein, alpha 0.389281
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.389281
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.382223
KDR kinase insert domain receptor 0.380368
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.380368
FST follistatin 0.374438
ACTA1 actin, alpha 1, skeletal muscle 0.374438
PARVA parvin, alpha 0.370368
HIST1H4B histone cluster 1, H4b 0.369258
HIST1H4A histone cluster 1, H4a 0.369258
HIST1H4F histone cluster 1, H4f 0.369258
HIST1H4E histone cluster 1, H4e 0.369258
HIST1H4C histone cluster 1, H4c 0.369258
HIST1H4D histone cluster 1, H4d 0.369258
HIST1H4K histone cluster 1, H4k 0.369258
HIST2H4B histone cluster 2, H4b 0.369258
HIST1H4J histone cluster 1, H4j 0.369258
HIST1H4I histone cluster 1, H4i 0.369258
HIST1H4H histone cluster 1, H4h 0.369258
HIST2H4A histone cluster 2, H4a 0.368518
HIST1H4L histone cluster 1, H4l 0.36704
HIST4H4 histone cluster 4, H4 0.366671
CSH2 chorionic somatomammotropin hormone 2 0.362239
MOGS mannosyl-oligosaccharide glucosidase 0.360395
AOC3 amine oxidase, copper containing 3 0.346042
RUNX3 runt-related transcription factor 3 0.338707
FANCB Fanconi anemia, complementation group B 0.320454
BRCA2 breast cancer 2, early onset 0.317545
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.311014
SEMG1 semenogelin I 0.306672
HRG histidine-rich glycoprotein 0.302337
MATN1 matrilin 1, cartilage matrix protein 0.301976
IFITM1 interferon induced transmembrane protein 1 0.300173
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.293694
FLAD1 flavin adenine dinucleotide synthetase 1 0.292616
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.289027
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.285086
TPM2 tropomyosin 2 (beta) 0.283655
RAP1A RAP1A, member of RAS oncogene family 0.28294
FASLG Fas ligand (TNF superfamily, member 6) 0.276158
GHR growth hormone receptor 0.273664
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.273664
TP73 tumor protein p73 0.270819
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.269753
CHMP2A charged multivesicular body protein 2A 0.266558
HBA1 hemoglobin, alpha 1 0.257711
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.257711
KITLG KIT ligand 0.243295
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.241895
MED12 mediator complex subunit 12 0.23945
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.238752
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.238054
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.237706
HBA2 hemoglobin, alpha 2 0.237357
CFL1 cofilin 1 (non-muscle) 0.234225
ADGRV1 adhesion G protein-coupled receptor V1 0.221793
TGFA transforming growth factor, alpha 0.220424
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.216672
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.215992
BRCA1 breast cancer 1, early onset 0.215314
CCND2 cyclin D2 0.212945
G6PD glucose-6-phosphate dehydrogenase 0.205916
SYK spleen tyrosine kinase 0.204923
HMGA2 high mobility group AT-hook 2 0.200982
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.198386
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.195501
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.188938
TIMP3 TIMP metallopeptidase inhibitor 3 0.188326
MUC1 mucin 1, cell surface associated 0.18591
SPP1 secreted phosphoprotein 1 0.184424
NGFR nerve growth factor receptor 0.182086
CD44 CD44 molecule (Indian blood group) 0.180937
FN1 fibronectin 1 0.178682
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.178403
TPM1 tropomyosin 1 (alpha) 0.177029
CMA1 chymase 1, mast cell 0.172799
CXXC1 CXXC finger protein 1 0.171785
HK1 hexokinase 1 0.171036
LAX1 lymphocyte transmembrane adaptor 1 0.170789
MIR21 microRNA 21 0.170789
VEGFA vascular endothelial growth factor A 0.170299
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.170299
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.166768
EFNB2 ephrin-B2 0.164149
AHR aryl hydrocarbon receptor 0.163111
MGAT4C MGAT4 family, member C 0.161523
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.161139
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.160021
PRRC2A proline-rich coiled-coil 2A 0.159658
IFNG interferon, gamma 0.146434
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.145791
WT1 Wilms tumor 1 0.143459
POMC proopiomelanocortin 0.141008