breast ductal carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A breast carcinoma that derives_from the lining of milk ducts. (Human Disease Ontology, DOID_3007)
Similar Terms
Downloads & Tools

Genes

245 genes co-occuring with the disease breast ductal carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ERBB2 erb-b2 receptor tyrosine kinase 2 2.39693
PGR progesterone receptor 2.19244
ESR1 estrogen receptor 1 2.04101
TP53 tumor protein p53 1.66195
EGFR epidermal growth factor receptor 1.45968
KRT5 keratin 5, type II 1.45792
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.34417
MUC2 mucin 2, oligomeric mucus/gel-forming 1.31886
MUC1 mucin 1, cell surface associated 1.21522
KRT14 keratin 14, type I 1.15198
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.05093
KRAS Kirsten rat sarcoma viral oncogene homolog 1.01765
KRT8 keratin 8, type II 1.00921
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.997814
PIP prolactin-induced protein 0.948685
MUC6 mucin 6, oligomeric mucus/gel-forming 0.946186
BRCA1 breast cancer 1, early onset 0.938704
HRAS Harvey rat sarcoma viral oncogene homolog 0.913903
CCND1 cyclin D1 0.893359
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) 0.870006
KRT7 keratin 7, type II 0.849126
KRT20 keratin 20, type I 0.814693
BRCA2 breast cancer 2, early onset 0.795821
SMAD4 SMAD family member 4 0.792541
ANAPC13 anaphase promoting complex subunit 13 0.781479
KLK3 kallikrein-related peptidase 3 0.777795
FAM50A family with sequence similarity 50, member A 0.768393
CD24 CD24 molecule 0.76431
CD34 CD34 molecule 0.763086
NUSAP1 nucleolar and spindle associated protein 1 0.746798
DEPDC1 DEP domain containing 1 0.742329
FBXO39 F-box protein 39 0.742329
CDKN2A cyclin-dependent kinase inhibitor 2A 0.735838
CDX2 caudal type homeobox 2 0.728143
PCNA proliferating cell nuclear antigen 0.715215
AR androgen receptor 0.692697
FAP fibroblast activation protein, alpha 0.687091
KIAA1671 KIAA1671 0.684292
SULF2 sulfatase 2 0.683892
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 0.681894
SHCBP1 SHC SH2-domain binding protein 1 0.681495
RHOXF1 Rhox homeobox family, member 1 0.658422
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.649323
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.648928
MUC4 mucin 4, cell surface associated 0.647348
ADAM9 ADAM metallopeptidase domain 9 0.640645
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.640251
RNF17 ring finger protein 17 0.639463
SYP synaptophysin 0.633956
SFN stratifin 0.630813
RIOK3 RIO kinase 3 0.619442
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.615921
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.593674
MIR21 microRNA 21 0.585497
CHGA chromogranin A 0.58005
LRRC15 leucine rich repeat containing 15 0.575383
CTNND1 catenin (cadherin-associated protein), delta 1 0.565277
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.556732
PITPNM3 PITPNM family member 3 0.552463
MMP11 matrix metallopeptidase 11 0.546644
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.538506
SYNJ2BP synaptojanin 2 binding protein 0.537731
RNF43 ring finger protein 43 0.532701
GPR139 G protein-coupled receptor 139 0.531928
CD44 CD44 molecule (Indian blood group) 0.526518
CTSD cathepsin D 0.52536
S100P S100 calcium binding protein P 0.517265
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.513417
STAT5A signal transducer and activator of transcription 5A 0.511112
RREB1 ras responsive element binding protein 1 0.507657
HBA2 hemoglobin, alpha 2 0.504207
CLTCL1 clathrin, heavy chain-like 1 0.503441
PLAU plasminogen activator, urokinase 0.503058
DMKN dermokine 0.501909
VASH1 vasohibin 1 0.500761
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.499997
PLXNA3 plexin A3 0.498467
FSCN3 fascin actin-bundling protein 3, testicular 0.494648
HBA1 hemoglobin, alpha 1 0.490835
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.490454
CD68 CD68 molecule 0.487407
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.486266
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.475255
AJUBA ajuba LIM protein 0.474877
FSCN2 fascin actin-bundling protein 2, retinal 0.467684
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.467306
TBX1 T-box 1 0.464283
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.459373
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.449947
MET MET proto-oncogene, receptor tyrosine kinase 0.448064
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.436402
CADM4 cell adhesion molecule 4 0.43227
EZR ezrin 0.429266
PDPN podoplanin 0.42664
TFF1 trefoil factor 1 0.42364
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.423265
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.42214
NKX2-1 NK2 homeobox 1 0.407919
NEK2 NIMA-related kinase 2 0.396353
VEGFA vascular endothelial growth factor A 0.387051
RRM2 ribonucleotide reductase M2 0.386308
PRLR prolactin receptor 0.385936
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.385193
PSCA prostate stem cell antigen 0.385193
KIF4A kinesin family member 4A 0.384079
DVL1 dishevelled segment polarity protein 1 0.382594
CEP55 centrosomal protein 55kDa 0.378514
SULF1 sulfatase 1 0.378143
PTEN phosphatase and tensin homolog 0.377031
FSCN1 fascin actin-bundling protein 1 0.371847
PLXNA2 plexin A2 0.371477
BIRC5 baculoviral IAP repeat containing 5 0.368518
MSLN mesothelin 0.366671
PGRMC2 progesterone receptor membrane component 2 0.359657
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.359657
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.356341
MMP2 matrix metallopeptidase 2 0.355972
ACKR3 atypical chemokine receptor 3 0.352659
RBBP7 retinoblastoma binding protein 7 0.351187
MKI67 marker of proliferation Ki-67 0.349717
TOP2A topoisomerase (DNA) II alpha 170kDa 0.346042
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.339073
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.339073
NRG4 neuregulin 4 0.336876
MMP9 matrix metallopeptidase 9 0.334681
PRKD1 protein kinase D1 0.334681
TYMP thymidine phosphorylase 0.334315
ZNF135 zinc finger protein 135 0.331756
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.331391
MFGE8 milk fat globule-EGF factor 8 protein 0.328105
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.32373
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.320454
CCNK cyclin K 0.320454
GLTSCR2 glioma tumor suppressor candidate region gene 2 0.316092
CCNI cyclin I 0.313552
SNAI1 snail family zinc finger 1 0.311739
BCL9L B-cell CLL/lymphoma 9-like 0.311014
SLC16A4 solute carrier family 16, member 4 0.309928
TNC tenascin C 0.307757
HELLS helicase, lymphoid-specific 0.307757
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.305226
RHOBTB2 Rho-related BTB domain containing 2 0.304142
EPCAM epithelial cell adhesion molecule 0.300894
UBE2T ubiquitin-conjugating enzyme E2T 0.300533
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.298371
DUSP6 dual specificity phosphatase 6 0.297651
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.293334
GSTP1 glutathione S-transferase pi 1 0.292616
PRB3 proline-rich protein BstNI subfamily 3 0.292616
HIST2H4B histone cluster 2, H4b 0.291539
HIST1H4B histone cluster 1, H4b 0.291539
HIST1H4H histone cluster 1, H4h 0.291539
ENO2 enolase 2 (gamma, neuronal) 0.291539
HIST1H4I histone cluster 1, H4i 0.291539
HIST1H4J histone cluster 1, H4j 0.291539
HIST1H4A histone cluster 1, H4a 0.291539
HIST1H4K histone cluster 1, H4k 0.291539
HIST1H4C histone cluster 1, H4c 0.291539
HIST1H4E histone cluster 1, H4e 0.291539
HIST1H4D histone cluster 1, H4d 0.291539
HIST1H4F histone cluster 1, H4f 0.291539
HIST2H4A histone cluster 2, H4a 0.290821
ANXA8 annexin A8 0.290462
HIST4H4 histone cluster 4, H4 0.289027
HIST1H4L histone cluster 1, H4l 0.289027
CAV1 caveolin 1, caveolae protein, 22kDa 0.28831
ACVR1C activin A receptor, type IC 0.286519
HDAC1 histone deacetylase 1 0.285086
PRKCI protein kinase C, iota 0.285086
PLAUR plasminogen activator, urokinase receptor 0.275445
CBX7 chromobox homolog 7 0.273308
FHIT fragile histidine triad 0.263368
STS steroid sulfatase (microsomal), isozyme S 0.263368
COL11A1 collagen, type XI, alpha 1 0.263368
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.26266
ASPN asporin 0.26266
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.25983
CXCL12 chemokine (C-X-C motif) ligand 12 0.257711
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.256652
CACYBP calcyclin binding protein 0.250663
CETN2 centrin, EF-hand protein, 2 0.247501
PITX2 paired-like homeodomain 2 0.246098
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.245046
ACPP acid phosphatase, prostate 0.244696
MRC2 mannose receptor, C type 2 0.244345
S100A9 S100 calcium binding protein A9 0.244345
HOXB9 homeobox B9 0.241196
RUNX3 runt-related transcription factor 3 0.240847
CLDN7 claudin 7 0.23666
CD8B CD8b molecule 0.235964
AMACR alpha-methylacyl-CoA racemase 0.23492
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.233878
VMP1 vacuole membrane protein 1 0.23353
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.233183
PTTG1 pituitary tumor-transforming 1 0.225229
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.224884
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.220424
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.217352
TRAF4 TNF receptor-associated factor 4 0.212945
F8 coagulation factor VIII, procoagulant component 0.212608
CTHRC1 collagen triple helix repeat containing 1 0.207912
ERBB3 erb-b2 receptor tyrosine kinase 3 0.207912
PSPH phosphoserine phosphatase 0.206913
S100A7 S100 calcium binding protein A7 0.206248
CST6 cystatin E/M 0.204923
UVRAG UV radiation resistance associated 0.196779
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.193915
CLDN6 claudin 6 0.1936
HOXD10 homeobox D10 0.193285
REG4 regenerating islet-derived family, member 4 0.192657
TAGLN2 transgelin 2 0.191719
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.189859
BAX BCL2-associated X protein 0.187719
RAB5A RAB5A, member RAS oncogene family 0.18621
MAX MYC associated factor X 0.18591
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.184128
ANGPTL2 angiopoietin-like 2 0.183248
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.183248
NDE1 nudE neurodevelopment protein 1 0.181222
FFAR4 free fatty acid receptor 4 0.181222
ADAM23 ADAM metallopeptidase domain 23 0.180084
SCGB3A1 secretoglobin, family 3A, member 1 0.179239
MIR197 microRNA 197 0.17896
ESRRG estrogen-related receptor gamma 0.178403
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.177029
NRG3 neuregulin 3 0.176215
WWOX WW domain containing oxidoreductase 0.173057
NOTCH1 notch 1 0.172038
CLDN18 claudin 18 0.170544
ANXA11 annexin A11 0.169571
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.16933
EGFL7 EGF-like-domain, multiple 7 0.167915
DLEC1 deleted in lung and esophageal cancer 1 0.167452
MMP13 matrix metallopeptidase 13 0.167224
GLI1 GLI family zinc finger 1 0.166319
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.165874
SYCN syncollin 0.164786
LIN9 lin-9 DREAM MuvB core complex component 0.164149
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.163938
FBXO42 F-box protein 42 0.162505
GRN granulin 0.161912
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 0.161716
SCGB1D1 secretoglobin, family 1D, member 1 0.15948
CSMD1 CUB and Sushi multiple domains 1 0.159302
ISL1 ISL LIM homeobox 1 0.158778