breast carcinoma in situ Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

283 genes co-occuring with the disease breast carcinoma in situ in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ERBB2 erb-b2 receptor tyrosine kinase 2 2.40776
ESR1 estrogen receptor 1 2.22072
PGR progesterone receptor 2.08128
KRT5 keratin 5, type II 1.69633
TP53 tumor protein p53 1.59653
EGFR epidermal growth factor receptor 1.44386
S100A7 S100 calcium binding protein A7 1.40176
BRCA1 breast cancer 1, early onset 1.39258
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.31974
KRT14 keratin 14, type I 1.31319
BRCA2 breast cancer 2, early onset 1.30532
PDPN podoplanin 1.24602
CCND1 cyclin D1 1.21348
KRT8 keratin 8, type II 1.11015
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.09755
ESR2 estrogen receptor 2 (ER beta) 0.97128
PIP prolactin-induced protein 0.936629
TRAF4 TNF receptor-associated factor 4 0.926692
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) 0.871234
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.860999
MYH11 myosin, heavy chain 11, smooth muscle 0.85404
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.818796
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.799923
ANAPC13 anaphase promoting complex subunit 13 0.782707
AR androgen receptor 0.767167
AAMP angio-associated, migratory cell protein 0.765943
SCGB3A1 secretoglobin, family 3A, member 1 0.747204
MUC1 mucin 1, cell surface associated 0.742329
C11ORF30 chromosome 11 open reading frame 30 0.726929
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.723694
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 0.718039
PRDM14 PR domain containing 14 0.709572
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.697109
SNX24 sorting nexin 24 0.6939
CDKN2A cyclin-dependent kinase inhibitor 2A 0.689492
SULF2 sulfatase 2 0.685491
KIAA1671 KIAA1671 0.685491
UPP2 uridine phosphorylase 2 0.685491
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 0.683093
MMP11 matrix metallopeptidase 11 0.668742
ADH6 alcohol dehydrogenase 6 (class V) 0.667947
SYP synaptophysin 0.663181
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.656046
PLAUR plasminogen activator, urokinase receptor 0.65565
CD44 CD44 molecule (Indian blood group) 0.655254
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.654463
CTSD cathepsin D 0.651694
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.641827
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.641039
HBA2 hemoglobin, alpha 2 0.631991
HBA1 hemoglobin, alpha 1 0.625711
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.622183
SYTL5 synaptotagmin-like 5 0.621008
CHMP3 charged multivesicular body protein 3 0.620617
CD24 CD24 molecule 0.618268
DYNLRB2 dynein, light chain, roadblock-type 2 0.615921
RUVBL1 RuvB-like AAA ATPase 1 0.60108
LRRC15 leucine rich repeat containing 15 0.576939
KLK10 kallikrein-related peptidase 10 0.57305
S100Z S100 calcium binding protein Z 0.567609
CST6 cystatin E/M 0.558674
ERBB3 erb-b2 receptor tyrosine kinase 3 0.553239
MTDH metadherin 0.552075
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.546256
MMP2 matrix metallopeptidase 2 0.544705
PLAU plasminogen activator, urokinase 0.544318
LARS leucyl-tRNA synthetase 0.535796
BLID BH3-like motif containing, cell death inducer 0.523816
CD34 CD34 molecule 0.51919
MAST2 microtubule associated serine/threonine kinase 2 0.518805
SFN stratifin 0.517265
KDM2A lysine (K)-specific demethylase 2A 0.515725
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.513417
PELP1 proline, glutamate and leucine rich protein 1 0.506123
CLTCL1 clathrin, heavy chain-like 1 0.50459
VASH1 vasohibin 1 0.501909
PLXNA3 plexin A3 0.499997
VEGFA vascular endothelial growth factor A 0.499614
MET MET proto-oncogene, receptor tyrosine kinase 0.496175
IGFBP7 insulin-like growth factor binding protein 7 0.492359
MKI67 marker of proliferation Ki-67 0.490072
CHGA chromogranin A 0.488169
DOK4 docking protein 4 0.482084
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.468819
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.467684
MMP26 matrix metallopeptidase 26 0.455601
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.452208
S100A9 S100 calcium binding protein A9 0.450324
GATA3 GATA binding protein 3 0.4443
MMP13 matrix metallopeptidase 13 0.443547
CD68 CD68 molecule 0.441666
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.435275
CADM4 cell adhesion molecule 4 0.433772
TMEM45A transmembrane protein 45A 0.42814
ADGRE2 adhesion G protein-coupled receptor E2 0.42814
SPRR1A small proline-rich protein 1A 0.426265
TYMP thymidine phosphorylase 0.42589
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.422515
MMP9 matrix metallopeptidase 9 0.42139
APOD apolipoprotein D 0.421016
PTEN phosphatase and tensin homolog 0.419142
NMT2 N-myristoyltransferase 2 0.417644
STS steroid sulfatase (microsomal), isozyme S 0.409787
EFTUD1 elongation factor Tu GTP binding domain containing 1 0.404557
HEATR6 HEAT repeat containing 6 0.401199
CTNND1 catenin (cadherin-associated protein), delta 1 0.398216
NEK2 NIMA-related kinase 2 0.397843
HMGN1 high mobility group nucleosome binding domain 1 0.394491
ERBB4 erb-b2 receptor tyrosine kinase 4 0.391141
NOTCH1 notch 1 0.390025
ZNF217 zinc finger protein 217 0.389653
RUNX3 runt-related transcription factor 3 0.388538
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.386308
ANXA1 annexin A1 0.385565
PCNA proliferating cell nuclear antigen 0.383708
SULF1 sulfatase 1 0.379626
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.379256
WDR77 WD repeat domain 77 0.378143
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.371477
CA9 carbonic anhydrase IX 0.369258
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.361133
PGRMC2 progesterone receptor membrane component 2 0.360764
AKAP4 A kinase (PRKA) anchor protein 4 0.360395
NUSAP1 nucleolar and spindle associated protein 1 0.360395
DEPDC1 DEP domain containing 1 0.356341
RBBP7 retinoblastoma binding protein 7 0.352659
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.350084
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.349349
FGFR1 fibroblast growth factor receptor 1 0.348246
CDH13 cadherin 13 0.346409
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.345675
NMU neuromedin U 0.343473
MIR21 microRNA 21 0.341639
MIR183 microRNA 183 0.341272
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.339806
TTL tubulin tyrosine ligase 0.33944
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.33944
TOP2A topoisomerase (DNA) II alpha 170kDa 0.336144
NRD1 nardilysin (N-arginine dibasic convertase) 0.333583
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.330295
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.322273
CCNK cyclin K 0.321909
CCNI cyclin I 0.315003
CCDC88A coiled-coil domain containing 88A 0.314278
BCL9L B-cell CLL/lymphoma 9-like 0.312464
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.31029
NOTCH4 notch 4 0.30342
BIRC5 baculoviral IAP repeat containing 5 0.300894
MIR145 microRNA 145 0.298731
MICB MHC class I polypeptide-related sequence B 0.298011
CCNE1 cyclin E1 0.293694
CDK11A cyclin-dependent kinase 11A 0.293334
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.292257
MUC2 mucin 2, oligomeric mucus/gel-forming 0.291898
CAV1 caveolin 1, caveolae protein, 22kDa 0.289386
ECI1 enoyl-CoA delta isomerase 1 0.289027
ACVR1C activin A receptor, type IC 0.287952
KRT7 keratin 7, type II 0.287235
PRKCI protein kinase C, iota 0.286519
CCND2 cyclin D2 0.283655
TP63 tumor protein p63 0.278297
GSTP1 glutathione S-transferase pi 1 0.27794
CDC6 cell division cycle 6 0.277584
LGALS3 lectin, galactoside-binding, soluble, 3 0.277584
RAB27B RAB27B, member RAS oncogene family 0.276514
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.275445
FHIT fragile histidine triad 0.272597
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.270108
ADAM9 ADAM metallopeptidase domain 9 0.264431
COL11A1 collagen, type XI, alpha 1 0.264431
ASPN asporin 0.264077
MMP7 matrix metallopeptidase 7 0.264077
PSRC1 proline/serine-rich coiled-coil 1 0.260891
ANXA8 annexin A8 0.25983
UPK1A uroplakin 1A 0.259124
KIAA0196 KIAA0196 0.258064
SFRP1 secreted frizzled-related protein 1 0.256652
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.253127
RAB11A RAB11A, member RAS oncogene family 0.250663
MRC2 mannose receptor, C type 2 0.245747
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.245396
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.244696
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.243295
CBX7 chromobox homolog 7 0.243295
MUC6 mucin 6, oligomeric mucus/gel-forming 0.243295
CXCR4 chemokine (C-X-C motif) receptor 4 0.241895
NCAM1 neural cell adhesion molecule 1 0.240847
DLL4 delta-like 4 (Drosophila) 0.237357
CA12 carbonic anhydrase XII 0.235964
TIMP1 TIMP metallopeptidase inhibitor 1 0.235268
VMP1 vacuole membrane protein 1 0.234573
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.234225
ANO7P1 anoctamin 7 pseudogene 1 0.233878
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.23353
MIR98 microRNA 98 0.233183
ENO2 enolase 2 (gamma, neuronal) 0.231795
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.228679
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.226262
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.225917
TRIP10 thyroid hormone receptor interactor 10 0.223853
MMP1 matrix metallopeptidase 1 0.221793
TGFB1 transforming growth factor, beta 1 0.22145
AKR1C3 aldo-keto reductase family 1, member C3 0.22145
KLHL21 kelch-like family member 21 0.220424
STK25 serine/threonine kinase 25 0.218034
JAG2 jagged 2 0.218034
CIRBP cold inducible RNA binding protein 0.216672
WT1 Wilms tumor 1 0.214297
HPSE heparanase 0.213621
VEGFC vascular endothelial growth factor C 0.212608
EPS8 epidermal growth factor receptor pathway substrate 8 0.210589
TIMP4 TIMP metallopeptidase inhibitor 4 0.209248
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.207578
SDC1 syndecan 1 0.205916
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.198709
S100A8 S100 calcium binding protein A8 0.198386
TBX1 T-box 1 0.197742
MIR210 microRNA 210 0.193285
TMPRSS3 transmembrane protease, serine 3 0.190786
MIR185 microRNA 185 0.190168
PLXNA1 plexin A1 0.188632
IGF2 insulin-like growth factor 2 0.188022
CCAR2 cell cycle and apoptosis regulator 2 0.187719
RAB5A RAB5A, member RAS oncogene family 0.187415
WWOX WW domain containing oxidoreductase 0.186811
TRIM27 tripartite motif containing 27 0.18651
FAM131C family with sequence similarity 131, member C 0.18621
ARRB1 arrestin, beta 1 0.185313
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.185016
ANGPTL2 angiopoietin-like 2 0.184424
FOXA1 forkhead box A1 0.183835
NCOR2 nuclear receptor corepressor 2 0.182957
DAP death-associated protein 0.182957
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.181222
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.180084
OPA1 optic atrophy 1 (autosomal dominant) 0.17952
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.177851
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.171785
RARB retinoic acid receptor, beta 0.171535
SIAH2 siah E3 ubiquitin protein ligase 2 0.170789
ANXA11 annexin A11 0.170299
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.169812
DLEC1 deleted in lung and esophageal cancer 1 0.168148
HRAS Harvey rat sarcoma viral oncogene homolog 0.167682
IGF2R insulin-like growth factor 2 receptor 0.166995
FOXM1 forkhead box M1 0.166544
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.166095
BIN2 bridging integrator 2 0.165874
ECT2 epithelial cell transforming 2 0.163317
EIF3A eukaryotic translation initiation factor 3, subunit A 0.161716
CDK4 cyclin-dependent kinase 4 0.161716
BCL2 B-cell CLL/lymphoma 2 0.161331
AKR1C4 aldo-keto reductase family 1, member C4 0.160387
S100P S100 calcium binding protein P 0.159658
VWF von Willebrand factor 0.159124
VANGL1 VANGL planar cell polarity protein 1 0.158778
MIRLET7D microRNA let-7d 0.158097
LINS lines homolog (Drosophila) 0.147116
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.144408
LXN latexin 0.144228
HNMT histamine N-methyltransferase 0.143668
PABPC1 poly(A) binding protein, cytoplasmic 1 0.143668
OXA1L oxidase (cytochrome c) assembly 1-like 0.143668
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.143665
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.143076
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.142387
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.142259
PRLR prolactin receptor 0.141307
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.141279
ANXA7 annexin A7 0.140887
KRT1 keratin 1, type II 0.140725
NBPF10 neuroblastoma breakpoint family, member 10 0.140364
STAT5A signal transducer and activator of transcription 5A 0.140032
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.139741
GIF gastric intrinsic factor (vitamin B synthesis) 0.139569
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.13575
ZNF135 zinc finger protein 135 0.135609
KRT20 keratin 20, type I 0.13348
KLK3 kallikrein-related peptidase 3 0.129823
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.126598
WISP2 WNT1 inducible signaling pathway protein 2 0.126531
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.126531
NRIP1 nuclear receptor interacting protein 1 0.126431