breast cancer Gene Set

Dataset PhosphoSitePlus Phosphosite-Disease Associations
Category disease or phenotype associations
Type disease
Description A thoracic cancer that originates in the mammary gland. (Human Disease Ontology, DOID_1612)
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Genes

26 proteins associated with the disease breast cancer from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset.

Symbol Name
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ATF4 activating transcription factor 4
BRCA2 breast cancer 2, early onset
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK1 checkpoint kinase 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FYN FYN proto-oncogene, Src family tyrosine kinase
GSK3B glycogen synthase kinase 3 beta
HIST1H3A histone cluster 1, H3a
HSPB1 heat shock 27kDa protein 1
ITGB4 integrin, beta 4
MKNK1 MAP kinase interacting serine/threonine kinase 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG1 phospholipase C, gamma 1
PTK2B protein tyrosine kinase 2 beta
RB1 retinoblastoma 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK3 serine/threonine kinase 3
TNK2 tyrosine kinase, non-receptor, 2
TWIST1 twist family bHLH transcription factor 1
YBX1 Y box binding protein 1