breast benign neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

189 genes co-occuring with the disease breast benign neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PGR progesterone receptor 1.46803
ESR1 estrogen receptor 1 1.32017
ERBB2 erb-b2 receptor tyrosine kinase 2 1.17035
CD34 CD34 molecule 1.00119
TP53 tumor protein p53 0.978426
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.95369
SYNJ2BP synaptojanin 2 binding protein 0.836427
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.833148
KRT15 keratin 15, type I 0.788442
PCNA proliferating cell nuclear antigen 0.765535
KRT14 keratin 14, type I 0.752492
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.727333
KRT8 keratin 8, type II 0.72612
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.718846
MKI67 marker of proliferation Ki-67 0.698313
KDM4A lysine (K)-specific demethylase 4A 0.672722
PIP prolactin-induced protein 0.672722
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.665563
MED19 mediator complex subunit 19 0.633169
KRT31 keratin 31, type I 0.610448
ESR2 estrogen receptor 2 (ER beta) 0.578106
F8 coagulation factor VIII, procoagulant component 0.577716
DOCK4 dedicator of cytokinesis 4 0.57655
ACVR1C activin A receptor, type IC 0.566831
KRT7 keratin 7, type II 0.565666
KRT5 keratin 5, type II 0.558674
AR androgen receptor 0.557897
RHEB Ras homolog enriched in brain 0.556732
RAB27B RAB27B, member RAS oncogene family 0.554403
PRL prolactin 0.554403
USP22 ubiquitin specific peptidase 22 0.553239
HIC1 hypermethylated in cancer 1 0.549359
EGFR epidermal growth factor receptor 0.529994
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.523816
GREM2 gremlin 2, DAN family BMP antagonist 0.507273
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.499614
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.493122
EFNA3 ephrin-A3 0.490835
PZP pregnancy-zone protein 0.483224
LAMA5 laminin, alpha 5 0.473361
WEE1 WEE1 G2 checkpoint kinase 0.465038
CLDN6 claudin 6 0.463149
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.445052
PELP1 proline, glutamate and leucine rich protein 1 0.442042
MMP2 matrix metallopeptidase 2 0.432646
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.427765
A1BG alpha-1-B glycoprotein 0.426265
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.422515
PLVAP plasmalemma vesicle associated protein 0.418019
CALR calreticulin 0.414276
NMU neuromedin U 0.411657
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.411283
HDAC1 histone deacetylase 1 0.410535
AMHR2 anti-Mullerian hormone receptor, type II 0.408292
VASH1 vasohibin 1 0.404557
WIBG within bgcn homolog (Drosophila) 0.398962
GRIK4 glutamate receptor, ionotropic, kainate 4 0.397098
DIO1 deiodinase, iodothyronine, type I 0.395608
MFGE8 milk fat globule-EGF factor 8 protein 0.385936
RARB retinoic acid receptor, beta 0.370368
FAP fibroblast activation protein, alpha 0.368518
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.368518
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.361133
KDR kinase insert domain receptor 0.359657
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.359657
ACTA1 actin, alpha 1, skeletal muscle 0.353763
FST follistatin 0.353763
PARVA parvin, alpha 0.349349
HIST1H4E histone cluster 1, H4e 0.348614
HIST1H4F histone cluster 1, H4f 0.348614
HIST2H4B histone cluster 2, H4b 0.348614
HIST1H4J histone cluster 1, H4j 0.348614
HIST1H4D histone cluster 1, H4d 0.348614
HIST1H4C histone cluster 1, H4c 0.348614
HIST1H4H histone cluster 1, H4h 0.348614
HIST1H4A histone cluster 1, H4a 0.348614
HIST1H4B histone cluster 1, H4b 0.348614
HIST1H4I histone cluster 1, H4i 0.348614
HIST1H4K histone cluster 1, H4k 0.348614
HIST2H4A histone cluster 2, H4a 0.347879
HIST4H4 histone cluster 4, H4 0.346042
HIST1H4L histone cluster 1, H4l 0.346042
CSH2 chorionic somatomammotropin hormone 2 0.341639
MOGS mannosyl-oligosaccharide glucosidase 0.339806
AOC3 amine oxidase, copper containing 3 0.325187
RUNX3 runt-related transcription factor 3 0.317909
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.307033
FANCB Fanconi anemia, complementation group B 0.300173
BRCA2 breast cancer 2, early onset 0.296931
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.290462
SEMG1 semenogelin I 0.286519
HRG histidine-rich glycoprotein 0.282225
MATN1 matrilin 1, cartilage matrix protein 0.281868
IFITM1 interferon induced transmembrane protein 1 0.279724
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.273664
FLAD1 flavin adenine dinucleotide synthetase 1 0.272597
NEK8 NIMA-related kinase 8 0.272597
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.269043
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.26514
CD44 CD44 molecule (Indian blood group) 0.263722
TPM2 tropomyosin 2 (beta) 0.263722
RAP1A RAP1A, member of RAS oncogene family 0.26266
FASLG Fas ligand (TNF superfamily, member 6) 0.256299
GHR growth hormone receptor 0.253831
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.253831
CTSD cathepsin D 0.251366
TP73 tumor protein p73 0.250663
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.24996
RBP1 retinol binding protein 1, cellular 0.248203
AGO2 argonaute RISC catalytic component 2 0.246799
CHMP2A charged multivesicular body protein 2A 0.246799
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.238054
HBA1 hemoglobin, alpha 1 0.237706
PPT1 palmitoyl-protein thioesterase 1 0.225917
KITLG KIT ligand 0.223853
FGF1 fibroblast growth factor 1 (acidic) 0.220766
MED12 mediator complex subunit 12 0.220081
PLG plasminogen 0.219398
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.218715
HBA2 hemoglobin, alpha 2 0.218034
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.218034
S100A10 S100 calcium binding protein A10 0.216672
CFL1 cofilin 1 (non-muscle) 0.214636
ADGRV1 adhesion G protein-coupled receptor V1 0.202618
TGFA transforming growth factor, alpha 0.201308
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.198064
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.19742
BRCA1 breast cancer 1, early onset 0.196779
CCND2 cyclin D2 0.194232
G6PD glucose-6-phosphate dehydrogenase 0.188022
SYK spleen tyrosine kinase 0.186811
HMGA2 high mobility group AT-hook 2 0.183541
ALPPL2 alkaline phosphatase, placental-like 2 0.182375
ALPP alkaline phosphatase, placental 0.182086
ALPL alkaline phosphatase, liver/bone/kidney 0.18151
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.181222
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.178403
TGFB1 transforming growth factor, beta 1 0.178403
ACPP acid phosphatase, prostate 0.176215
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.173057
CCND1 cyclin D1 0.172544
TIMP3 TIMP metallopeptidase inhibitor 3 0.172544
MUC1 mucin 1, cell surface associated 0.170299
SPP1 secreted phosphoprotein 1 0.16933
NGFR nerve growth factor receptor 0.167452
FN1 fibronectin 1 0.164571
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.164359
TPM1 tropomyosin 1 (alpha) 0.163317
CXXC1 CXXC finger protein 1 0.159658
HK1 hexokinase 1 0.159124
MIR21 microRNA 21 0.158951
VEGFA vascular endothelial growth factor A 0.158605
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.158434
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.139475
CD68 CD68 molecule 0.137279
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.136884
SRY sex determining region Y 0.135528
PTEN phosphatase and tensin homolog 0.132059
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.119569
TRH thyrotropin-releasing hormone 0.105791
SYP synaptophysin 0.103743
CMA1 chymase 1, mast cell 0.102889
LAX1 lymphocyte transmembrane adaptor 1 0.102522
CALD1 caldesmon 1 0.1021
IFNG interferon, gamma 0.093062
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.091878
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.090862
LALBA lactalbumin, alpha- 0.090282
H2AFX H2A histone family, member X 0.086539
DES desmin 0.082168
WT1 Wilms tumor 1 0.0797
CDKN2A cyclin-dependent kinase inhibitor 2A 0.078191
KLK3 kallikrein-related peptidase 3 0.071263
POMC proopiomelanocortin 0.070407
CHGA chromogranin A 0.07004
CD72 CD72 molecule 0.068599
SRSF1 serine/arginine-rich splicing factor 1 0.06808
FGFR1 fibroblast growth factor receptor 1 0.067605
PLAT plasminogen activator, tissue 0.065269
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.06477
IGF2 insulin-like growth factor 2 0.063166
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.060609
EFNB2 ephrin-B2 0.060349
AHR aryl hydrocarbon receptor 0.06024
GFAP glial fibrillary acidic protein 0.06011
MGAT4C MGAT4 family, member C 0.060067
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.059894
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.059872
PRRC2A proline-rich coiled-coil 2A 0.059851