breast adenocarcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast. (Human Disease Ontology, DOID_3458)
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Genes

329 genes co-occuring with the disease breast adenocarcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CALCA calcitonin-related polypeptide alpha 2.08637
ALPPL2 alkaline phosphatase, placental-like 2 2.02839
ALPP alkaline phosphatase, placental 2.02794
ALPL alkaline phosphatase, liver/bone/kidney 2.02703
SQSTM1 sequestosome 1 1.69633
VCP valosin containing protein 1.6525
PIP prolactin-induced protein 1.61575
KRT7 keratin 7, type II 1.57868
ERBB2 erb-b2 receptor tyrosine kinase 2 1.53436
BGLAP bone gamma-carboxyglutamate (gla) protein 1.40964
ESR1 estrogen receptor 1 1.30226
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.19575
GPR176 G protein-coupled receptor 176 1.18884
MUC21 mucin 21, cell surface associated 1.16949
KRT20 keratin 20, type I 1.16307
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 1.13374
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.07908
PTH parathyroid hormone 1.06606
TP53 tumor protein p53 1.05429
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.0168
PGR progesterone receptor 0.988114
ACPP acid phosphatase, prostate 0.984743
CTSC cathepsin C 0.964986
ERI3 ERI1 exoribonuclease family member 3 0.909787
MUC4 mucin 4, cell surface associated 0.877376
CST9 cystatin 9 (testatin) 0.839705
MUC1 mucin 1, cell surface associated 0.819616
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.804026
NMU neuromedin U 0.800744
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.788033
PRSS3 protease, serine, 3 0.788033
MX1 MX dynamin-like GTPase 1 0.786394
MMP17 matrix metallopeptidase 17 (membrane-inserted) 0.782298
FDPS farnesyl diphosphate synthase 0.772887
CORO2A coronin, actin binding protein, 2A 0.736649
MFGE8 milk fat globule-EGF factor 8 protein 0.732191
EGFR epidermal growth factor receptor 0.729762
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.725311
KRT8 keratin 8, type II 0.724907
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.718039
EBAG9 estrogen receptor binding site associated, antigen, 9 0.709975
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.707157
KRT5 keratin 5, type II 0.699517
IL2 interleukin 2 0.696707
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.694702
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.665563
UBXN6 UBX domain protein 6 0.660008
HPSE heparanase 0.657234
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.641433
NRARP NOTCH-regulated ankyrin repeat protein 0.633956
ADPRH ADP-ribosylarginine hydrolase 0.625711
FICD FIC domain containing 0.613965
BAX BCL2-associated X protein 0.613574
CDH20 cadherin 20, type 2 0.60303
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.594064
TNF tumor necrosis factor 0.586276
TGFB1 transforming growth factor, beta 1 0.581996
COL1A2 collagen, type I, alpha 2 0.580439
TUSC5 tumor suppressor candidate 5 0.578494
DEGS2 delta(4)-desaturase, sphingolipid 2 0.577716
GTF2B general transcription factor IIB 0.572662
CCDC62 coiled-coil domain containing 62 0.569552
C9ORF24 chromosome 9 open reading frame 24 0.569552
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.565666
PCCA propionyl CoA carboxylase, alpha polypeptide 0.561781
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.559839
ADGRF5 adhesion G protein-coupled receptor F5 0.558674
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.550911
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.550911
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.542379
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 0.538118
CSN1S1 casein alpha s1 0.537344
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.534635
CDH7 cadherin 7, type 2 0.522273
TGDS TDP-glucose 4,6-dehydratase 0.508041
FAM195A family with sequence similarity 195, member A 0.506507
NOA1 nitric oxide associated 1 0.501527
MUC2 mucin 2, oligomeric mucus/gel-forming 0.498467
ANKRD42 ankyrin repeat domain 42 0.494648
ANXA5 annexin A5 0.491978
SYNJ2BP synaptojanin 2 binding protein 0.489311
SLC16A6 solute carrier family 16, member 6 0.474498
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 0.469197
FN1 fibronectin 1 0.467684
PGM3 phosphoglucomutase 3 0.467306
STAT5A signal transducer and activator of transcription 5A 0.462772
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 0.459751
GSTA4 glutathione S-transferase alpha 4 0.455978
AR androgen receptor 0.452208
MIER1 mesoderm induction early response 1, transcriptional regulator 0.449947
MAEA macrophage erythroblast attacher 0.449194
EFHD1 EF-hand domain family, member D1 0.447687
FOS FBJ murine osteosarcoma viral oncogene homolog 0.445052
LALBA lactalbumin, alpha- 0.4443
CTSK cathepsin K 0.437906
CSRP1 cysteine and glycine-rich protein 1 0.436026
MMP9 matrix metallopeptidase 9 0.434899
GSTK1 glutathione S-transferase kappa 1 0.42814
MPZL2 myelin protein zero-like 2 0.425139
IL6 interleukin 6 0.424014
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 0.42214
TOP1 topoisomerase (DNA) I 0.418019
ADK adenosine kinase 0.413901
GSTA3 glutathione S-transferase alpha 3 0.411657
GSTA2 glutathione S-transferase alpha 2 0.410535
MTPAP mitochondrial poly(A) polymerase 0.409787
GSTA1 glutathione S-transferase alpha 1 0.403438
CD4 CD4 molecule 0.400826
HOOK1 hook microtubule-tethering protein 1 0.398216
LRP5 low density lipoprotein receptor-related protein 5 0.397098
F2 coagulation factor II (thrombin) 0.394491
GPR182 G protein-coupled receptor 182 0.393001
CDX2 caudal type homeobox 2 0.390025
ATF7 activating transcription factor 7 0.382966
TICAM2 toll-like receptor adaptor molecule 2 0.382966
PLAU plasminogen activator, urokinase 0.379626
DNAH8 dynein, axonemal, heavy chain 8 0.371847
KRT14 keratin 14, type I 0.371477
GH2 growth hormone 2 0.368518
S100A6 S100 calcium binding protein A6 0.356709
PTHLH parathyroid hormone-like hormone 0.355972
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.354868
CDH19 cadherin 19, type 2 0.35082
PGRMC2 progesterone receptor membrane component 2 0.345675
UPP1 uridine phosphorylase 1 0.344941
SPDEF SAM pointed domain containing ETS transcription factor 0.344207
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.34384
S100A1 S100 calcium binding protein A1 0.342739
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.341639
LGALS7 lectin, galactoside-binding, soluble, 7 0.337975
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.336876
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.333583
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.333218
RIN3 Ras and Rab interactor 3 0.331391
NQO1 NAD(P)H dehydrogenase, quinone 1 0.33066
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.326646
MN1 meningioma (disrupted in balanced translocation) 1 0.32373
MOCS1 molybdenum cofactor synthesis 1 0.323002
ANXA1 annexin A1 0.321181
PXN paxillin 0.320454
GABARAPL1 GABA(A) receptor-associated protein like 1 0.320454
CDY2A chromodomain protein, Y-linked, 2A 0.319726
PDPN podoplanin 0.319363
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.315003
CALCR calcitonin receptor 0.314278
MT1M metallothionein 1M 0.312102
ZHX2 zinc fingers and homeoboxes 2 0.311739
S100P S100 calcium binding protein P 0.307757
S100A4 S100 calcium binding protein A4 0.307757
IL4I1 interleukin 4 induced 1 0.303781
FHOD1 formin homology 2 domain containing 1 0.302698
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.302698
ARL2 ADP-ribosylation factor-like 2 0.301976
GH1 growth hormone 1 0.300533
CCL16 chemokine (C-C motif) ligand 16 0.298371
TSPO translocator protein (18kDa) 0.298371
LOX lysyl oxidase 0.298011
IBSP integrin-binding sialoprotein 0.298011
SST somatostatin 0.298011
ATF2 activating transcription factor 2 0.295492
DIAPH1 diaphanous-related formin 1 0.290103
PARP1 poly (ADP-ribose) polymerase 1 0.284728
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.284728
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.283655
DAAM2 dishevelled associated activator of morphogenesis 2 0.283655
FMNL2 formin-like 2 0.282225
WDR74 WD repeat domain 74 0.278654
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.27794
IGF1 insulin-like growth factor 1 (somatomedin C) 0.277227
LONP1 lon peptidase 1, mitochondrial 0.275801
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.272953
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.272953
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.270108
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.269753
GRIK2 glutamate receptor, ionotropic, kainate 2 0.267977
KIN Kin17 DNA and RNA binding protein 0.265494
PDCL2 phosducin-like 2 0.261952
FMNL1 formin-like 1 0.261599
ATR ATR serine/threonine kinase 0.25983
S100A2 S100 calcium binding protein A2 0.25983
CCND1 cyclin D1 0.259477
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.257358
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.256652
LPO lactoperoxidase 0.256299
ESR2 estrogen receptor 2 (ER beta) 0.251718
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.251015
CSNK1E casein kinase 1, epsilon 0.248203
MMRN1 multimerin 1 0.246448
ZNF224 zinc finger protein 224 0.245046
CCNB1 cyclin B1 0.244696
PRAMEF10 PRAME family member 10 0.243995
GGPS1 geranylgeranyl diphosphate synthase 1 0.243645
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.243295
FSCN1 fascin actin-bundling protein 1 0.238752
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.236312
INS insulin 0.232836
THY1 Thy-1 cell surface antigen 0.231102
KRT15 keratin 15, type I 0.229716
EFNA1 ephrin-A1 0.228333
IFNA1 interferon, alpha 1 0.226952
RGMA repulsive guidance molecule family member a 0.221108
HRAS Harvey rat sarcoma viral oncogene homolog 0.220424
EPHA2 EPH receptor A2 0.219398
RPS26 ribosomal protein S26 0.217693
AHSG alpha-2-HS-glycoprotein 0.217693
IRX2 iroquois homeobox 2 0.215653
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.215314
DIAPH2 diaphanous-related formin 2 0.214636
RNF25 ring finger protein 25 0.213283
ALB albumin 0.213283
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.208914
CTSD cathepsin D 0.208914
MTA1 metastasis associated 1 0.208914
TYMS thymidylate synthetase 0.208579
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.206913
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.206248
PLG plasminogen 0.204923
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.203933
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.203604
OPTN optineurin 0.203604
CENPJ centromere protein J 0.202618
KRT2 keratin 2, type II 0.192971
LTA lymphotoxin alpha 0.190476
RHOB ras homolog family member B 0.189859
DRAM1 DNA-damage regulated autophagy modulator 1 0.189244
COL18A1 collagen, type XVIII, alpha 1 0.188938
VEGFA vascular endothelial growth factor A 0.187415
CDK1 cyclin-dependent kinase 1 0.187415
KLK3 kallikrein-related peptidase 3 0.187113
ACP5 acid phosphatase 5, tartrate resistant 0.18621
WNT16 wingless-type MMTV integration site family, member 16 0.183835
PBX2 pre-B-cell leukemia homeobox 2 0.18151
ICMT isoprenylcysteine carboxyl methyltransferase 0.179802
NTHL1 nth endonuclease III-like 1 (E. coli) 0.179239
BECN1 beclin 1, autophagy related 0.179239
HK1 hexokinase 1 0.178126
MAML1 mastermind-like 1 (Drosophila) 0.177029
SNX15 sorting nexin 15 0.177029
MMP1 matrix metallopeptidase 1 0.175947
ALK anaplastic lymphoma receptor tyrosine kinase 0.173832
TOP2A topoisomerase (DNA) II alpha 170kDa 0.172799
AMPH amphiphysin 0.172291
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.171535
CDY1B chromodomain protein, Y-linked, 1B 0.169571
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.16933
HMX2 H6 family homeobox 2 0.168854
SARS seryl-tRNA synthetase 0.168148
DAAM1 dishevelled associated activator of morphogenesis 1 0.166768
FOXO3 forkhead box O3 0.166544
C1ORF174 chromosome 1 open reading frame 174 0.165001
FMN2 formin 2 0.162707
UVRAG UV radiation resistance associated 0.162505
JUP junction plakoglobin 0.160021
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.15948
CIITA class II, major histocompatibility complex, transactivator 0.158778
SCGB3A2 secretoglobin, family 3A, member 2 0.158778
RTN4R reticulon 4 receptor 0.158097
ANXA2 annexin A2 0.158097
CLDN3 claudin 3 0.157929
BRCA1 breast cancer 1, early onset 0.136175
IGHV3-30 immunoglobulin heavy variable 3-30 0.133743
SLC16A4 solute carrier family 16, member 4 0.133646
ETV6 ets variant 6 0.133523
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.133338
IGLV7-43 immunoglobulin lambda variable 7-43 0.132449
BRCA2 breast cancer 2, early onset 0.131718
CISH cytokine inducible SH2-containing protein 0.128632
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.12614
WISP3 WNT1 inducible signaling pathway protein 3 0.123842
CALR calreticulin 0.12349
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.123209
PIDD1 p53-induced death domain protein 1 0.123164
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.123057
CDKN2A cyclin-dependent kinase inhibitor 2A 0.122965
CA9 carbonic anhydrase IX 0.12195
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.120335
SYP synaptophysin 0.120265
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.12023
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.118029
PROM1 prominin 1 0.117875
MARK2 MAP/microtubule affinity-regulating kinase 2 0.117577
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.117398
TXN thioredoxin 0.117199
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.116213
HES5 hes family bHLH transcription factor 5 0.116149
FGFR1 fibroblast growth factor receptor 1 0.115916
NOTCH3 notch 3 0.115556
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.114277
PRF1 perforin 1 (pore forming protein) 0.113849
NOTCH4 notch 4 0.113849
ANKRD11 ankyrin repeat domain 11 0.110492
PBX1 pre-B-cell leukemia homeobox 1 0.109589
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.109067
MET MET proto-oncogene, receptor tyrosine kinase 0.108423
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.105369
FASLG Fas ligand (TNF superfamily, member 6) 0.10502
CDK4 cyclin-dependent kinase 4 0.101141
TG thyroglobulin 0.100917
SELE selectin E 0.098772
MMP12 matrix metallopeptidase 12 0.098302
EPCAM epithelial cell adhesion molecule 0.095357
IGHV5-51 immunoglobulin heavy variable 5-51 0.095323
TBCA tubulin folding cofactor A 0.093942
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.093729
APEH acylaminoacyl-peptide hydrolase 0.092063
NANOG Nanog homeobox 0.091582
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.090282
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.090282
MNX1 motor neuron and pancreas homeobox 1 0.090207
CD24 CD24 molecule 0.09017
MED1 mediator complex subunit 1 0.089569
ERBB4 erb-b2 receptor tyrosine kinase 4 0.088734
SOX2 SRY (sex determining region Y)-box 2 0.088504
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.088199
DPEP1 dipeptidase 1 (renal) 0.088199
MMP19 matrix metallopeptidase 19 0.087818
TARDBP TAR DNA binding protein 0.087624
SPTBN1 spectrin, beta, non-erythrocytic 1 0.086732
LYZ lysozyme 0.086693
CD207 CD207 molecule, langerin 0.086655
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.086539
UBQLN2 ubiquilin 2 0.083975
INSC inscuteable homolog (Drosophila) 0.083935
LITAF lipopolysaccharide-induced TNF factor 0.083776
MAPK14 mitogen-activated protein kinase 14 0.083616
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.083537
KRT19 keratin 19, type I 0.083056
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.082895
DLC1 DLC1 Rho GTPase activating protein 0.08241