break Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

143 genes co-occuring with the biological term break in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
APLF aprataxin and PNKP like factor
APP amyloid beta (A4) precursor protein
APTX aprataxin
AR androgen receptor
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
BBC3 BCL2 binding component 3
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTBD2 BTB (POZ) domain containing 2
BTG2 BTG family, member 2
C7ORF49 chromosome 7 open reading frame 49
CALCA calcitonin-related polypeptide alpha
CCNA1 cyclin A1
CDK2 cyclin-dependent kinase 2
CECR2 cat eye syndrome chromosome region, candidate 2
COL1A1 collagen, type I, alpha 1
COL4A5 collagen, type IV, alpha 5
CPA6 carboxypeptidase A6
CYFIP1 cytoplasmic FMR1 interacting protein 1
DCLRE1C DNA cross-link repair 1C
DEK DEK proto-oncogene
DNA2 DNA replication helicase/nuclease 2
DTX3L deltex 3 like, E3 ubiquitin ligase
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGFR epidermal growth factor receptor
ERCC1 excision repair cross-complementation group 1
ERCC4 excision repair cross-complementation group 4
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
FANCD2 Fanconi anemia, complementation group D2
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FRA6E fragile site, aphidicolin type, common, fra(6)(q26)
FSCN1 fascin actin-bundling protein 1
FXN frataxin
GEN1 GEN1 Holliday junction 5' flap endonuclease
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIPK2 homeodomain interacting protein kinase 2
HMGA2 high mobility group AT-hook 2
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL7 interleukin 7
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
INO80 INO80 complex subunit
JAK2 Janus kinase 2
KDM4D lysine (K)-specific demethylase 4D
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MIR429 microRNA 429
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP9 matrix metallopeptidase 9
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NABP2 nucleic acid binding protein 2
NAMPT nicotinamide phosphoribosyltransferase
NBN nibrin
NEK1 NIMA-related kinase 1
NHEJ1 nonhomologous end-joining factor 1
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
PARD3 par-3 family cell polarity regulator
PARG poly (ADP-ribose) glycohydrolase
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PARP9 poly (ADP-ribose) polymerase family, member 9
PDGFB platelet-derived growth factor beta polypeptide
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNKP polynucleotide kinase 3'-phosphatase
POLM polymerase (DNA directed), mu
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSG2 pregnancy specific beta-1-glycoprotein 2
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAD18 RAD18 E3 ubiquitin protein ligase
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RBBP8 retinoblastoma binding protein 8
RECQL RecQ helicase-like
REV1 REV1, polymerase (DNA directed)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF169 ring finger protein 169
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPA4 replication protein A4, 30kDa
RSF1 remodeling and spacing factor 1
RTEL1 regulator of telomere elongation helicase 1
SETX senataxin
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SUB1 SUB1 homolog (S. cerevisiae)
TDP1 tyrosyl-DNA phosphodiesterase 1
TERF2 telomeric repeat binding factor 2
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TUBGCP5 tubulin, gamma complex associated protein 5
UBE2N ubiquitin-conjugating enzyme E2N
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6