brain edema Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

187 genes co-occuring with the disease brain edema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AQP4 aquaporin 4 2.65527
OCLN occludin 1.6651
CLDN5 claudin 5 1.66465
MMP9 matrix metallopeptidase 9 1.61083
ALB albumin 1.41534
TJP1 tight junction protein 1 1.41446
AQP1 aquaporin 1 (Colton blood group) 1.28566
KNG1 kininogen 1 1.27214
SOD2 superoxide dismutase 2, mitochondrial 1.22388
HMOX1 heme oxygenase 1 1.19532
AQP9 aquaporin 9 1.13924
AVP arginine vasopressin 1.13797
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.12361
PLAT plasminogen activator, tissue 1.10973
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.10804
GLUL glutamate-ammonia ligase 1.08412
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 1.04462
DNTT DNA nucleotidylexotransferase 1.03704
VEGFA vascular endothelial growth factor A 1.00879
SLC38A5 solute carrier family 38, member 5 0.978848
TNF tumor necrosis factor 0.97212
AQP3 aquaporin 3 (Gill blood group) 0.962053
AQP5 aquaporin 5 0.933313
GFAP glial fibrillary acidic protein 0.928346
MMP2 matrix metallopeptidase 2 0.926692
MPO myeloperoxidase 0.925039
RICTOR RPTOR independent companion of MTOR, complex 2 0.919673
TJP2 tight junction protein 2 0.914727
NFE2L2 nuclear factor, erythroid 2-like 2 0.890488
IL1B interleukin 1, beta 0.870006
HSPA4 heat shock 70kDa protein 4 0.851992
ICAM1 intercellular adhesion molecule 1 0.804026
ASS1 argininosuccinate synthase 1 0.791311
BDKRB2 bradykinin receptor B2 0.787213
HMGB1 high mobility group box 1 0.778204
EVA1A eva-1 homolog A (C. elegans) 0.763494
NOS3 nitric oxide synthase 3 (endothelial cell) 0.74436
BAX BCL2-associated X protein 0.740705
IL6 interleukin 6 0.738271
GPX1 glutathione peroxidase 1 0.718443
GPX5 glutathione peroxidase 5 0.706351
GPX4 glutathione peroxidase 4 0.702732
BDKRB1 bradykinin receptor B1 0.701928
DNAH8 dynein, axonemal, heavy chain 8 0.691094
MAP2 microtubule-associated protein 2 0.675112
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.673518
S100B S100 calcium binding protein B 0.666755
F2R coagulation factor II (thrombin) receptor 0.657234
CYSLTR2 cysteinyl leukotriene receptor 2 0.654067
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.652089
NPPA natriuretic peptide A 0.650903
CTXN3 cortexin 3 0.649323
NQO1 NAD(P)H dehydrogenase, quinone 1 0.641433
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.635135
OTC ornithine carbamoyltransferase 0.625319
TLR4 toll-like receptor 4 0.616312
JUN jun proto-oncogene 0.59913
TUBG1 tubulin, gamma 1 0.596402
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.591337
TSPO translocator protein (18kDa) 0.572662
TIMP1 TIMP metallopeptidase inhibitor 1 0.568775
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.562946
AQP12A aquaporin 12A 0.559062
PLA2G1B phospholipase A2, group IB (pancreas) 0.556344
TSPAN16 tetraspanin 16 0.505739
AIF1 allograft inflammatory factor 1 0.501144
BECN1 beclin 1, autophagy related 0.497321
GDNF glial cell derived neurotrophic factor 0.490454
BOP1 block of proliferation 1 0.488169
AQP8 aquaporin 8 0.487407
PES1 pescadillo ribosomal biogenesis factor 1 0.471846
CAT catalase 0.461261
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.452962
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.447687
ANGPT1 angiopoietin 1 0.445805
CAV1 caveolin 1, caveolae protein, 22kDa 0.433021
CLDN3 claudin 3 0.427765
OPA1 optic atrophy 1 (autosomal dominant) 0.425514
HRH3 histamine receptor H3 0.424765
IPO8 importin 8 0.419517
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.419142
PARP1 poly (ADP-ribose) polymerase 1 0.413901
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.410535
DUOX1 dual oxidase 1 0.408666
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.408666
AQP11 aquaporin 11 0.402318
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.392629
DUOX2 dual oxidase 2 0.388538
FAT3 FAT atypical cadherin 3 0.386679
HRH2 histamine receptor H2 0.382966
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.372587
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.36704
PAOX polyamine oxidase (exo-N4-amino) 0.366671
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.362609
TRIM37 tripartite motif containing 37 0.357446
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.354131
MAP4 microtubule-associated protein 4 0.353027
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.339073
C5 complement component 5 0.338341
RTKN rhotekin 0.337608
SH3PXD2B SH3 and PX domains 2B 0.336144
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.334681
CYSLTR1 cysteinyl leukotriene receptor 1 0.333218
BEND3 BEN domain containing 3 0.32993
RPS6 ribosomal protein S6 0.329565
BBC3 BCL2 binding component 3 0.329565
MGAM maltase-glucoamylase 0.325552
CARD17 caspase recruitment domain family, member 17 0.319363
MAGEE1 melanoma antigen family E1 0.317909
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.317545
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.31029
CRH corticotropin releasing hormone 0.306672
ENO2 enolase 2 (gamma, neuronal) 0.300533
FPR2 formyl peptide receptor 2 0.300173
C7ORF49 chromosome 7 open reading frame 49 0.297651
GLS glutaminase 0.296931
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.293334
PDYN prodynorphin 0.292616
MYL12B myosin, light chain 12B, regulatory 0.290462
FTL ferritin, light polypeptide 0.289027
FTH1 ferritin, heavy polypeptide 1 0.288668
BDNF brain-derived neurotrophic factor 0.287593
PLAU plasminogen activator, urokinase 0.286877
DRAM1 DNA-damage regulated autophagy modulator 1 0.285444
CNOT2 CCR4-NOT transcription complex, subunit 2 0.285086
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.278654
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.278297
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.278297
FLT1 fms-related tyrosine kinase 1 0.276514
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.272953
FABP3 fatty acid binding protein 3, muscle and heart 0.272953
IK IK cytokine, down-regulator of HLA II 0.269398
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.267267
HMOX2 heme oxygenase 2 0.266203
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.264785
MYLK3 myosin light chain kinase 3 0.260538
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.258417
CDH5 cadherin 5, type 2 (vascular endothelium) 0.258417
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.255594
PLG plasminogen 0.254183
CTNND1 catenin (cadherin-associated protein), delta 1 0.249257
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.244345
F8 coagulation factor VIII, procoagulant component 0.242245
INS insulin 0.241895
AQP2 aquaporin 2 (collecting duct) 0.240847
DDN dendrin 0.238054
CLDN1 claudin 1 0.232836
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.230755
ADGRL4 adhesion G protein-coupled receptor L4 0.224196
TP53 tumor protein p53 0.222479
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.220766
CLDN7 claudin 7 0.220424
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.217352
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.216672
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.216332
NOS1 nitric oxide synthase 1 (neuronal) 0.212608
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.211261
MFF mitochondrial fission factor 0.210589
TCHH trichohyalin 0.200656
S1PR1 sphingosine-1-phosphate receptor 1 0.200656
TFRC transferrin receptor 0.198064
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.192971
PC pyruvate carboxylase 0.191719
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.191097
TLR2 toll-like receptor 2 0.188938
UCN urocortin 0.18621
F2 coagulation factor II (thrombin) 0.182957
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.180937
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.179239
IFITM3 interferon induced transmembrane protein 3 0.17896
GPR17 G protein-coupled receptor 17 0.178403
NPS neuropeptide S 0.177576
GSR glutathione reductase 0.175146
AGTR2 angiotensin II receptor, type 2 0.174881
FRMD6 FERM domain containing 6 0.173832
HSPA1A heat shock 70kDa protein 1A 0.173571
GLS2 glutaminase 2 (liver, mitochondrial) 0.168854
NT5E 5'-nucleotidase, ecto (CD73) 0.167224
SPHK1 sphingosine kinase 1 0.163938
PRPF4B pre-mRNA processing factor 4B 0.162109
CREB1 cAMP responsive element binding protein 1 0.160948
RASD1 RAS, dexamethasone-induced 1 0.160203
AQP7 aquaporin 7 0.159838
CA1 carbonic anhydrase I 0.158951
TLK1 tousled-like kinase 1 0.158434
ALOX5 arachidonate 5-lipoxygenase 0.158266
ERCC6L excision repair cross-complementation group 6-like 0.157929