brain disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

168 genes associated with the disease brain disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CRHR1-IT1 CRHR1 intronic transcript 1 1.70133
LRRK2 leucine-rich repeat kinase 2 1.68372
PRNP prion protein 1.43016
WNT3 wingless-type MMTV integration site family, member 3 1.2206
BST1 bone marrow stromal cell antigen 1 1.17894
TWIST1 twist family bHLH transcription factor 1 1.14929
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.14929
CCDC62 coiled-coil domain containing 62 0.932337
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.894262
RAB25 RAB25, member RAS oncogene family 0.850113
CPQ carboxypeptidase Q 0.790827
HDAC9 histone deacetylase 9 0.790827
SYK spleen tyrosine kinase 0.738873
MEF2D myocyte enhancer factor 2D 0.738873
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.682635
LINGO1 leucine rich repeat and Ig domain containing 1 0.63207
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.63207
NINJ2 ninjurin 2 0.63207
VRK2 vaccinia related kinase 2 0.602429
CTIF CBP80/20-dependent translation initiation factor 0.602429
GAK cyclin G associated kinase 0.58494
PRDM16 PR domain containing 16 0.572184
NFE2L1 nuclear factor, erythroid 2-like 1 0.5306
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.52461
ADAMTSL1 ADAMTS-like 1 0.52461
ZFHX3 zinc finger homeobox 3 0.486425
RNF213 ring finger protein 213 0.486425
MTMR7 myotubularin related protein 7 0.486425
PHACTR1 phosphatase and actin regulator 1 0.464771
COL27A1 collagen, type XXVII, alpha 1 0.464771
WIPF3 WAS/WASL interacting protein family, member 3 0.464771
TMEM175 transmembrane protein 175 0.449873
CHRM3 cholinergic receptor, muscarinic 3 0.449873
NPAS2 neuronal PAS domain protein 2 0.449873
ASTN2 astrotactin 2 0.449873
RREB1 ras responsive element binding protein 1 0.438544
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.438544
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.438544
ASB3 ankyrin repeat and SOCS box containing 3 0.438544
TMEM55A transmembrane protein 55A 0.438544
STMN2 stathmin 2 0.429338
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.429338
UFL1 UFM1-specific ligase 1 0.429338
SREBF1 sterol regulatory element binding transcription factor 1 0.429338
ARL15 ADP-ribosylation factor-like 15 0.4215
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.4215
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.4215
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.408752
MMRN1 multimerin 1 0.403461
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.403461
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 0.403461
HYI hydroxypyruvate isomerase (putative) 0.403461
KANSL1 KAT8 regulatory NSL complex subunit 1 0.368757
CCDC82 coiled-coil domain containing 82 0.368757
ACMSD aminocarboxymuconate semialdehyde decarboxylase 0.368757
MAPT microtubule-associated protein tau 0.368757
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.368757
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.368757
SPPL2C signal peptide peptidase like 2C 0.368757
TMC3 transmembrane channel-like 3 0.368757
RIT2 Ras-like without CAAX 2 0.368757
MAST4 microtubule associated serine/threonine kinase family member 4 0.345945
ELOVL4 ELOVL fatty acid elongase 4 0.345945
SH3BGRL SH3 domain binding glutamate-rich protein like 0.345945
UNC13C unc-13 homolog C (C. elegans) 0.345945
FAM47E family with sequence similarity 47, member E 0.327313
PRSS53 protease, serine, 53 0.327313
TAS1R2 taste receptor, type 1, member 2 0.311576
PRKCH protein kinase C, eta 0.311576
SH3GL2 SH3-domain GRB2-like 2 0.311576
AXIN1 axin 1 0.311576
PRND prion protein 2 (dublet) 0.311576
QSER1 glutamine and serine rich 1 0.311576
MMP17 matrix metallopeptidase 17 (membrane-inserted) 0.311576
C1ORF94 chromosome 1 open reading frame 94 0.297866
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 0.297866
COL13A1 collagen, type XIII, alpha 1 0.297866
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.285417
DAPL1 death associated protein-like 1 0.285417
CNKSR3 CNKSR family member 3 0.264872
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.256228
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.256228
NSF N-ethylmaleimide-sensitive factor 0.256228
ADCY9 adenylate cyclase 9 0.256228
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.256228
STAP1 signal transducing adaptor family member 1 0.256228
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.256228
CTSB cathepsin B 0.256228
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.256228
FRY furry homolog (Drosophila) 0.197766
TMEM72 transmembrane protein 72 0.197766
DIAPH3 diaphanous-related formin 3 0.197766
TSPAN8 tetraspanin 8 0.197766
ZBTB38 zinc finger and BTB domain containing 38 0.197766
DGKQ diacylglycerol kinase, theta 110kDa 0.197766
PKNOX2 PBX/knotted 1 homeobox 2 0.197766
DLG2 discs, large homolog 2 (Drosophila) 0.197766
CSMD1 CUB and Sushi multiple domains 1 0.197766
PARD3 par-3 family cell polarity regulator 0.197766
USP15 ubiquitin specific peptidase 15 0.15771
UNC13B unc-13 homolog B (C. elegans) 0.15771
MIR4315-2 microRNA 4315-2 0.15771
ADGRL3 adhesion G protein-coupled receptor L3 0.15771
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.15771
STK39 serine threonine kinase 39 0.15771
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.15771
IGSF5 immunoglobulin superfamily, member 5 0.15771
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.15771
SLC45A3 solute carrier family 45, member 3 0.15771
RAP1A RAP1A, member of RAS oncogene family 0.15771
RBMS3 RNA binding motif, single stranded interacting protein 3 0.15771
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.15771
OCA2 oculocutaneous albinism II 0.15771
CLRN3 clarin 3 0.126165
C9 complement component 9 0.126165
DSG3 desmoglein 3 0.126165
GPM6B glycoprotein M6B 0.126165
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.126165
USP36 ubiquitin specific peptidase 36 0.126165
ULK2 unc-51 like autophagy activating kinase 2 0.126165
SCN1A sodium channel, voltage gated, type I alpha subunit 0.126165
ZNF385D zinc finger protein 385D 0.100789
C4ORF26 chromosome 4 open reading frame 26 0.100789
LINC00587 long intergenic non-protein coding RNA 587 0.100789
LMNB1 lamin B1 0.100789
TASP1 taspase, threonine aspartase, 1 0.100789
ITGA8 integrin, alpha 8 0.100789
PRDM15 PR domain containing 15 0.100789
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.100789
TBATA thymus, brain and testes associated 0.080593
SPANXN3 SPANX family, member N3 0.080593
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.080593
MAP2K6 mitogen-activated protein kinase kinase 6 0.080593
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.080593
PHEX phosphate regulating endopeptidase homolog, X-linked 0.080593
PCGF5 polycomb group ring finger 5 0.080593
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.080593
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.080593
MEOX2 mesenchyme homeobox 2 0.080593
OTOG otogelin 0.080593
THSD7A thrombospondin, type I, domain containing 7A 0.080593
ATRIP ATR interacting protein 0.064973
ADCY8 adenylate cyclase 8 (brain) 0.064973
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.064973
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.064973
IGLL1 immunoglobulin lambda-like polypeptide 1 0.052255
HDGFL1 hepatoma derived growth factor-like 1 0.052255
SCN2A sodium channel, voltage gated, type II alpha subunit 0.052255
LMO2 LIM domain only 2 (rhombotin-like 1) 0.052255
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.052255
ATF6 activating transcription factor 6 0.052255
ETV6 ets variant 6 0.052255
AAK1 AP2 associated kinase 1 0.043246
PTPRD protein tyrosine phosphatase, receptor type, D 0.043246
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 0.043246
CTC1 CTS telomere maintenance complex component 1 0.043246
CYB5RL cytochrome b5 reductase-like 0.043246
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.043246
INA internexin neuronal intermediate filament protein, alpha 0.043246
AIM1 absent in melanoma 1 0.043246
RNF114 ring finger protein 114 0.043246
KIAA0020 KIAA0020 0.043246
RPL14P1 ribosomal protein L14 pseudogene 1 0.043246
SURF6 surfeit 6 0.043246
PICALM phosphatidylinositol binding clathrin assembly protein 0.043246
TCF12 transcription factor 12 0.043246
OR9G1 olfactory receptor, family 9, subfamily G, member 1 0.035343
DPP6 dipeptidyl-peptidase 6 0.001277