brain cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain. (Human Disease Ontology, DOID_1319)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1319
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Genes

33 genes associated with the disease brain cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
TERT telomerase reverse transcriptase 1.90896
CDKN2B-AS1 CDKN2B antisense RNA 1 1.84833
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.80338
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.70759
RTEL1 regulator of telomere elongation helicase 1 1.67004
PHLDB1 pleckstrin homology-like domain, family B, member 1 1.59609
KIF26B kinesin family member 26B 1.44448
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.43429
SMYD3 SET and MYND domain containing 3 1.36676
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.33802
EGFR epidermal growth factor receptor 1.33186
DBT dihydrolipoamide branched chain transacylase E2 1.30111
TRAF5 TNF receptor-associated factor 5 1.24952
ACOT11 acyl-CoA thioesterase 11 1.2111
SSBP2 single-stranded DNA binding protein 2 1.19386
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.14065
MIR205HG MIR205 host gene 1.11123
KAZN kazrin, periplakin interacting protein 1.0538
CCDC23 coiled-coil domain containing 23 0.960778
RLF rearranged L-myc fusion 0.947208
PLD5 phospholipase D family, member 5 0.886521
HIAT1 hippocampus abundant transcript 1 0.858922
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0.848917
SASS6 spindle assembly 6 homolog (C. elegans) 0.82729
OR2M7 olfactory receptor, family 2, subfamily M, member 7 0.748112
LEPR leptin receptor 0.74095
LRP1B low density lipoprotein receptor-related protein 1B 0.736436
PARD3B par-3 family cell polarity regulator beta 0.731685
ANKAR ankyrin and armadillo repeat containing 0.722673
VWA3B von Willebrand factor A domain containing 3B 0.691138
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.691138
SRBD1 S1 RNA binding domain 1 0.686457
SPP2 secreted phosphoprotein 2, 24kDa 0.679107