borderline personality disorder Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A personality disorder that involves a prolonged disturbance of personality function characterized by depth and variability of moods. (Human Disease Ontology, DOID_10930)
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Genes

98 genes co-occuring with the disease borderline personality disorder in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ZAN zonadhesin (gene/pseudogene) 2.23832
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.67955
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.42937
CLPS colipase, pancreatic 1.42279
TPH1 tryptophan hydroxylase 1 1.3952
CGA glycoprotein hormones, alpha polypeptide 1.37381
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1.32279
FLNA filamin A, alpha 1.30663
GAN gigaxonin 1.24645
MAOA monoamine oxidase A 1.22605
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.21825
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.17593
OXT oxytocin/neurophysin I prepropeptide 1.14263
TRH thyrotropin-releasing hormone 1.06396
NXF5 nuclear RNA export factor 5 0.973801
COMT catechol-O-methyltransferase 0.95369
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.934556
NXF1 nuclear RNA export factor 1 0.899514
SPAG5 sperm associated antigen 5 0.895
PEG10 paternally expressed 10 0.876966
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.875329
NXF2 nuclear RNA export factor 2 0.851173
NXF2B nuclear RNA export factor 2B 0.851173
TENM4 teneurin transmembrane protein 4 0.849945
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.84544
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.845031
NPAS4 neuronal PAS domain protein 4 0.842982
MRPL49 mitochondrial ribosomal protein L49 0.827409
NPS neuropeptide S 0.81059
AVPR1A arginine vasopressin receptor 1A 0.788852
NINJ2 ninjurin 2 0.785165
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.764718
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.758601
NRXN3 neurexin 3 0.75005
PNP purine nucleoside phosphorylase 0.711183
BDNF brain-derived neurotrophic factor 0.696707
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.686291
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.660404
AMY1B amylase, alpha 1B (salivary) 0.65763
AMY1C amylase, alpha 1C (salivary) 0.65763
AMY1A amylase, alpha 1A (salivary) 0.65763
TPH2 tryptophan hydroxylase 2 0.63907
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.613574
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.606152
SHB Src homology 2 domain containing adaptor protein B 0.595233
DRD4 dopamine receptor D4 0.594843
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.58005
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.571884
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.568386
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.544705
CRH corticotropin releasing hormone 0.519961
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.494648
CLOCK clock circadian regulator 0.484744
ADAR adenosine deaminase, RNA-specific 0.480945
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.479047
HOXD13 homeobox D13 0.477151
AGPS alkylglycerone phosphate synthase 0.476014
BCO1 beta-carotene oxygenase 1 0.469954
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.468441
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.435275
FKBP5 FK506 binding protein 5 0.433772
IPP intracisternal A particle-promoted polypeptide 0.42814
MCF2 MCF.2 cell line derived transforming sequence 0.420641
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 0.41465
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.40008
PRL prolactin 0.394118
CHD7 chromodomain helicase DNA binding protein 7 0.373698
TXNL4B thioredoxin-like 4B 0.372217
SLITRK1 SLIT and NTRK-like family, member 1 0.356709
KNTC1 kinetochore associated 1 0.355604
OXTR oxytocin receptor 0.354868
OPRM1 opioid receptor, mu 1 0.354499
POMC proopiomelanocortin 0.348614
MAOB monoamine oxidase B 0.32993
NTSR1 neurotensin receptor 1 (high affinity) 0.321545
ARRB1 arrestin, beta 1 0.318999
DRD2 dopamine receptor D2 0.316456
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.315729
TPT1 tumor protein, translationally-controlled 1 0.30342
APP amyloid beta (A4) precursor protein 0.297291
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.296571
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.287235
MFGE8 milk fat globule-EGF factor 8 protein 0.271886
IL6 interleukin 6 0.263014
SCN3A sodium channel, voltage gated, type III alpha subunit 0.257005
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.235268
C10ORF2 chromosome 10 open reading frame 2 0.22454
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.222136
ILK integrin-linked kinase 0.209918
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.209583
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.207245
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.196459
TACR1 tachykinin receptor 1 0.192971
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.18651
GATA4 GATA binding protein 4 0.177576
PYY peptide YY 0.177301
TNF tumor necrosis factor 0.176757
LEP leptin 0.160948