boldine-4122 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the boldine-4122 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
AHSP alpha hemoglobin stabilizing protein
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ATN1 atrophin 1
AVPR1B arginine vasopressin receptor 1B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP1 bone morphogenetic protein 1
BMP2K BMP2 inducible kinase
C1ORF95 chromosome 1 open reading frame 95
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC28B coiled-coil domain containing 28B
CD209 CD209 molecule
CD22 CD22 molecule
CD5 CD5 molecule
CEP112 centrosomal protein 112kDa
CFHR4 complement factor H-related 4
CLCN4 chloride channel, voltage-sensitive 4
CLPS colipase, pancreatic
COL5A2 collagen, type V, alpha 2
COL9A3 collagen, type IX, alpha 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCTN2 dynactin 2 (p50)
DLC1 DLC1 Rho GTPase activating protein
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOK2 docking protein 2, 56kDa
DSC2 desmocollin 2
DUSP6 dual specificity phosphatase 6
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDA ectodysplasin A
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
ETV5 ets variant 5
EXT1 exostosin glycosyltransferase 1
FAM134B family with sequence similarity 134, member B
FLOT1 flotillin 1
FXYD5 FXYD domain containing ion transport regulator 5
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GHRHR growth hormone releasing hormone receptor
GLDC glycine dehydrogenase (decarboxylating)
GYPB glycophorin B (MNS blood group)
HAUS6 HAUS augmin-like complex, subunit 6
HOXB5 homeobox B5
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSPG2 heparan sulfate proteoglycan 2
ICA1 islet cell autoantigen 1, 69kDa
IDS iduronate 2-sulfatase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHMBP2 immunoglobulin mu binding protein 2
IL2 interleukin 2
ING2 inhibitor of growth family, member 2
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1107 KIAA1107
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KSR1 kinase suppressor of ras 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAL mal, T-cell differentiation protein
MATN3 matrilin 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MTSS1L metastasis suppressor 1-like
NF1 neurofibromin 1
NOL10 nucleolar protein 10
NPR1 natriuretic peptide receptor 1
NREP neuronal regeneration related protein
NUDCD3 NudC domain containing 3
ONECUT2 one cut homeobox 2
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PCDHGA8 protocadherin gamma subfamily A, 8
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKNOX1 PBX/knotted 1 homeobox 1
PLLP plasmolipin
PPARD peroxisome proliferator-activated receptor delta
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKG2 protein kinase, cGMP-dependent, type II
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RIBC2 RIB43A domain with coiled-coils 2
RND1 Rho family GTPase 1
RSU1 Ras suppressor protein 1
SEPP1 selenoprotein P, plasma, 1
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SSX3 synovial sarcoma, X breakpoint 3
SUGP1 SURP and G patch domain containing 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
UBOX5 U-box domain containing 5
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF155 zinc finger protein 155
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMH anti-Mullerian hormone
APLP1 amyloid beta (A4) precursor-like protein 1
BATF basic leucine zipper transcription factor, ATF-like
C7ORF69 chromosome 7 open reading frame 69
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CAPN5 calpain 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK3 cyclin-dependent kinase 3
CEL carboxyl ester lipase
CENPO centromere protein O
CFAP45 cilia and flagella associated protein 45
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CIDEB cell death-inducing DFFA-like effector b
CLCA1 chloride channel accessory 1
CLCF1 cardiotrophin-like cytokine factor 1
CLSTN2 calsyntenin 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAGLA diacylglycerol lipase, alpha
DGAT1 diacylglycerol O-acyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
FAM186A family with sequence similarity 186, member A
FAM46C family with sequence similarity 46, member C
FMOD fibromodulin
FRMD1 FERM domain containing 1
FUZ fuzzy planar cell polarity protein
GMPR guanosine monophosphate reductase
GRIP2 glutamate receptor interacting protein 2
HDAC11 histone deacetylase 11
HIST1H2AK histone cluster 1, H2ak
HIST1H3E histone cluster 1, H3e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSPA2 heat shock 70kDa protein 2
IL11RA interleukin 11 receptor, alpha
INPP5J inositol polyphosphate-5-phosphatase J
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF5A kinesin family member 5A
KLHL25 kelch-like family member 25
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT13 keratin 13, type I
KRT83 keratin 83, type II
LEFTY2 left-right determination factor 2
LIG3 ligase III, DNA, ATP-dependent
LIN7B lin-7 homolog B (C. elegans)
LINC00341 long intergenic non-protein coding RNA 341
LMO2 LIM domain only 2 (rhombotin-like 1)
LMTK2 lemur tyrosine kinase 2
MAGEH1 melanoma antigen family H1
MED15 mediator complex subunit 15
MIR622 microRNA 622
MST1 macrophage stimulating 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NNAT neuronatin
NOTCH1 notch 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PORCN porcupine homolog (Drosophila)
PROL1 proline rich, lacrimal 1
PTPRM protein tyrosine phosphatase, receptor type, M
RAB30 RAB30, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
ROM1 retinal outer segment membrane protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
RUSC2 RUN and SH3 domain containing 2
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGK2 serum/glucocorticoid regulated kinase 2
SHPK sedoheptulokinase
SIPA1 signal-induced proliferation-associated 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SNTA1 syntrophin, alpha 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STK16 serine/threonine kinase 16
TBC1D19 TBC1 domain family, member 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM57 transmembrane protein 57
TRABD TraB domain containing
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZSWIM1 zinc finger, SWIM-type containing 1