blood coagulation disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1247
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Genes

158 genes associated with the disease blood coagulation disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
KNG1 kininogen 1 3.47985
F13A1 coagulation factor XIII, A1 polypeptide 3.43409
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 3.21162
STX4 syntaxin 4 3.17726
HRG histidine-rich glycoprotein 3.13034
KAT8 K(lysine) acetyltransferase 8 3.09285
F12 coagulation factor XII (Hageman factor) 2.95687
PFN3 profilin 3 2.6554
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.62533
MCF2L MCF.2 cell line derived transforming sequence-like 2.52923
BCL7C B-cell CLL/lymphoma 7C 2.52748
STX1B syntaxin 1B 2.52553
VKORC1 vitamin K epoxide reductase complex, subunit 1 2.50286
SETD1A SET domain containing 1A 2.48036
F11 coagulation factor XI 2.47539
PROCR protein C receptor, endothelial 2.38133
F10 coagulation factor X 2.35168
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 2.27887
F13B coagulation factor XIII, B polypeptide 2.27644
CFHR5 complement factor H-related 5 2.2661
RGS14 regulator of G-protein signaling 14 2.22889
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.22503
ZBTB41 zinc finger and BTB domain containing 41 2.21677
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.21287
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.12428
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.10888
STXBP5 syntaxin binding protein 5 (tomosyn) 2.0844
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.06032
NSD1 nuclear receptor binding SET domain protein 1 2.00072
PYCARD PYD and CARD domain containing 1.97708
CFHR4 complement factor H-related 4 1.97122
FUS FUS RNA binding protein 1.96889
FBXL19 F-box and leucine-rich repeat protein 19 1.96807
CFHR2 complement factor H-related 2 1.95661
BCKDK branched chain ketoacid dehydrogenase kinase 1.89
GRK6 G protein-coupled receptor kinase 6 1.86227
VWF von Willebrand factor 1.84833
GSS glutathione synthetase 1.81328
ACSS2 acyl-CoA synthetase short-chain family member 2 1.80793
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.79613
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.75292
CFH complement factor H 1.72214
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.7088
LMAN2 lectin, mannose-binding 2 1.68305
SRCAP Snf2-related CREBBP activator protein 1.66269
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 1.64364
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.63592
PRR14 proline rich 14 1.62969
LY86-AS1 LY86 antisense RNA 1 1.61421
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 1.61367
ITCH itchy E3 ubiquitin protein ligase 1.59743
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.59599
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.58293
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.57804
CKAP5 cytoskeleton associated protein 5 1.56813
ORM1 orosomucoid 1 1.55738
LRP4 low density lipoprotein receptor-related protein 4 1.55285
FGFR4 fibroblast growth factor receptor 4 1.54765
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 1.54533
STKLD1 serine/threonine kinase-like domain containing 1 1.53438
UNC5A unc-5 homolog A (C. elegans) 1.50873
SURF4 surfeit 4 1.50171
DBN1 drebrin 1 1.48767
FLJ33360 FLJ33360 protein 1.48714
F5 coagulation factor V (proaccelerin, labile factor) 1.47287
KCNT2 potassium channel, sodium activated subfamily T, member 2 1.45324
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.43605
PRR7 proline rich 7 (synaptic) 1.37833
AGBL1 ATP/GTP binding protein-like 1 1.35834
CES1 carboxylesterase 1 1.24194
C6ORF10 chromosome 6 open reading frame 10 1.21996
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 1.19386
CNBD2 cyclic nucleotide binding domain containing 2 1.15988
NME7 NME/NM23 family member 7 1.14463
GCKR glucokinase (hexokinase 4) regulator 1.11581
PHF20 PHD finger protein 20 1.11444
FER1L4 fer-1-like family member 4, pseudogene (functional) 1.10135
NFS1 NFS1 cysteine desulfurase 1.07464
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 1.07092
ROMO1 reactive oxygen species modulator 1 1.06948
CPNE1 copine I 1.03828
RBM12 RNA binding motif protein 12 1.02671
C11ORF49 chromosome 11 open reading frame 49 0.971169
CUX2 cut-like homeobox 2 0.964504
RALY RALY heterogeneous nuclear ribonucleoprotein 0.951641
FAM83C family with sequence similarity 83, member C 0.888385
HNF4A hepatocyte nuclear factor 4, alpha 0.882888
AHCY adenosylhomocysteinase 0.836437
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.802597
ASIP agouti signaling protein 0.75315
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.735881
EIF6 eukaryotic translation initiation factor 6 0.680789
GGT7 gamma-glutamyltransferase 7 0.545524
CHMP4B charged multivesicular body protein 4B 0.504373
ERCC3 excision repair cross-complementation group 3 0.47629
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.475435
GDF5 growth differentiation factor 5 0.47325
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 0.472257
PEAR1 platelet endothelial aggregation receptor 1 0.459543
NCOA6 nuclear receptor coactivator 6 0.441357
RBM39 RNA binding motif protein 39 0.439762
ERGIC3 ERGIC and golgi 3 0.438534
C20ORF173 chromosome 20 open reading frame 173 0.43721
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.435705
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 0.431631
MYO7B myosin VIIB 0.381289
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.376404
SURF2 surfeit 2 0.369114
GPN1 GPN-loop GTPase 1 0.368213
IWS1 IWS1 homolog (S. cerevisiae) 0.363231
ZNF512 zinc finger protein 512 0.359058
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.355381
C2ORF16 chromosome 2 open reading frame 16 0.35337
C4BPB complement component 4 binding protein, beta 0.348788
GLIS3 GLIS family zinc finger 3 0.347523
C20ORF194 chromosome 20 open reading frame 194 0.341532
CEP250 centrosomal protein 250kDa 0.340582
TP53INP2 tumor protein p53 inducible nuclear protein 2 0.332314
APOA5 apolipoprotein A-V 0.32908
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.326269
MME membrane metallo-endopeptidase 0.321503
NDRG3 NDRG family member 3 0.317284
SOGA1 suppressor of glucose, autophagy associated 1 0.315085
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.313906
OR9G1 olfactory receptor, family 9, subfamily G, member 1 0.310428
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.309888
SPAG4 sperm associated antigen 4 0.306301
IPCEF1 interaction protein for cytohesin exchange factors 1 0.301866
LDHAL6A lactate dehydrogenase A-like 6A 0.298713
PCGF5 polycomb group ring finger 5 0.296746
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.294525
ZNF583 zinc finger protein 583 0.292577
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.287595
NEURL1 neuralized E3 ubiquitin protein ligase 1 0.287595
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.28481
ZPR1 ZPR1 zinc finger 0.283548
PRKCQ protein kinase C, theta 0.280212
BUD13 BUD13 homolog (S. cerevisiae) 0.271985
MRVI1 murine retrovirus integration site 1 homolog 0.266139
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.266139
MEAF6 MYST/Esa1-associated factor 6 0.259848
NEGR1 neuronal growth regulator 1 0.25952
ASIC2 acid sensing (proton gated) ion channel 2 0.256658
PDGFC platelet derived growth factor C 0.250833
STAB2 stabilin 2 0.250475
SGCZ sarcoglycan, zeta 0.242809
ANKRD6 ankyrin repeat domain 6 0.242809
MYH15 myosin, heavy chain 15 0.242809
ATG4C autophagy related 4C, cysteine peptidase 0.241021
PCGF3 polycomb group ring finger 3 0.240105
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.240105
CD82 CD82 molecule 0.237833
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.237833
VAV2 vav 2 guanine nucleotide exchange factor 0.235873
DPYD dihydropyrimidine dehydrogenase 0.225086
ESR1 estrogen receptor 1 0.220543
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.216314
NRG1 neuregulin 1 0.210852